期刊
SCIENCE OF THE TOTAL ENVIRONMENT
卷 654, 期 -, 页码 452-455出版社
ELSEVIER
DOI: 10.1016/j.scitotenv.2018.11.166
关键词
Marine bacteriophages; Environmental reservoirs; Antibiotic resistance genes
资金
- Economy and Knowledge Department of the Catalan Government [ICRA-ENV 2017 SGR 1124]
Although antibiotic resistance represents a significant and growing threat to human and environmental health worldwide, the contribution of bacteriophages (phages) to the acquisition and spread of antibiotic resistance genes (ARGs) in the environment has not been extensively explored. In this study, a comprehensive analysis of several viromes from diverse marine habitats was performed to investigate whether or not phages carry ARGs. The analysis provides strong evidence that phages from marine habitats are potential reservoirs of ARGs. In fact, genes conferring resistance to aminocoumarin, bacitracin and multidrug resistance (particularly the mexB gene) were found in all analyzed marine viromes. Given this, the role of phages as reservoirs of ARGs should not be underestimated considering their global distribution. (C) 2018 Elsevier B.V. All rights reserved.
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