Bisubstrate analogues as structural tools to investigate m6A methyltransferase active sites

Synthesis of SAM-adenosine conjugates for the study of m6A-RNA methyltransferases.

(2018) Colette Atdjian et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

RNA-modifying proteins as anticancer drug targets

(2018) P. Ann Boriack-Sjodin et al.   NATURE REVIEWS DRUG DISCOVERY

Structural Insights into N 6 -methyladenosine (m 6 A) Modification in the Transcriptome

(2018) Jinbo Huang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor

(2018) Katelyn A. Doxtader et al.   MOLECULAR CELL

Structural insights into the RNA methyltransferase domain of METTL16

(2018) Agnieszka Ruszkowska et al.   Scientific Reports

MODOMICS: a database of RNA modification pathways. 2017 update

(2017) Pietro Boccaletto et al.   NUCLEIC ACIDS RESEARCH

Recessive Mutations in TRMT10C Cause Defects in Mitochondrial RNA Processing and Multiple Respiratory Chain Deficiencies

(2016) Metodi D. Metodiev et al.   AMERICAN JOURNAL OF HUMAN GENETICS

N6-Methylated Adenosine in RNA: From Bacteria to Humans

(2016) Petr V. Sergiev et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases

(2016) Ping Wang et al.   MOLECULAR CELL

Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex

(2016) Xiang Wang et al.   NATURE

Dali server update

(2016) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

Deficient methylation and formylation of mt-tRNAMet wobble cytosine in a patient carrying mutations in NSUN3

(2016) Lindsey Van Haute et al.   Nature Communications

Structural insights into the molecular mechanism of the m6A writer complex

(2016) Paweł Śledź et al.   eLife

Structural Chemistry of Human RNA Methyltransferases

(2015) Matthieu Schapira   ACS Chemical Biology

Discovery of a Dual PRMT5–PRMT7 Inhibitor

(2015) David Smil et al.   ACS Medicinal Chemistry Letters

Structural and functional insights into the molecular mechanism of rRNA m6A methyltransferase RlmJ

(2013) Avinash S. Punekar et al.   NUCLEIC ACIDS RESEARCH

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Genome-wide screen for Escherichia coli genes involved in repressing cell-to-cell transfer of non-conjugative plasmids

(2012) Ayako Matsuda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The last rRNA methyltransferase of E. coli revealed: The yhiR gene encodes adenine-N6 methyltransferase specific for modification of A2030 of 23S ribosomal RNA

(2012) A. Y. Golovina et al.   RNA

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Systematic errors in isothermal titration calorimetry: Concentrations and baselines

(2011) Joel Tellinghuisen et al.   ANALYTICAL BIOCHEMISTRY

Selective Killing of Mixed Lineage Leukemia Cells by a Potent Small-Molecule DOT1L Inhibitor

(2011) Scott R. Daigle et al.   CANCER CELL

The RNA modification database, RNAMDB: 2011 update

(2010) W. A. Cantara et al.   NUCLEIC ACIDS RESEARCH

The YqfN protein of Bacillus subtilis is the tRNA: m 1 A22 methyltransferase (TrmK)

(2008) Martine Roovers et al.   NUCLEIC ACIDS RESEARCH