Article
Radiology, Nuclear Medicine & Medical Imaging
Minha Kwag, Sang Hyun Choi, Se Jin Choi, Jae Ho Byun, Hyung Jin Won, Yong Moon Shin
Summary: The study evaluated the clinical usefulness of a simplified LI-RADS for diagnosing hepatocellular carcinomas (HCCs) of 30 mm or smaller at gadoxetic acid-enhanced MRI. The results showed that the simplified LI-RADS demonstrated higher sensitivity and reduced time for category assignment compared to LI-RADS 2018.
Article
Radiology, Nuclear Medicine & Medical Imaging
Ji Hye Min, Seong Hyun Kim, Jeong Ah Hwang, Seung Hyup Hyun, Sang Yun Ha, Seo-Youn Choi, Seon Woo Kim, Hye Seung Kim
Summary: Both LI-RADS category on MRI and TLR on PET-CT are associated with the postoperative prognosis of PLCs. The prognosis of PLCs classified as LR-M can be further stratified according to the TLR group, but not for the PLCs classified as LR-4/5.
EUROPEAN RADIOLOGY
(2021)
Article
Oncology
Ruizhi Wang, Hengtian Xu, Wufei Chen, Liang Jin, Zhuangxuan Ma, Lei Wen, Hongwei Wang, Kun Cao, Xia Du, Ming Li
Summary: This study investigated the role of gadoxetic acid-enhanced MRI based on LI-RADS v2018 imaging features in the prognosis prediction of sHCC patients treated with RFA. A total of 204 patients were enrolled, and a predictive nomogram was formulated. The nomogram showed superior predictive performance in both the training and validation groups.
FRONTIERS IN ONCOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hong Wei, Hanyu Jiang, Tianying Zheng, Zhen Zhang, Caiwei Yang, Zheng Ye, Ting Duan, Bin Song
Summary: This study investigated the role of preoperative gadoxetic acid-enhanced MRI in stratifying the risk of early recurrence in LR-5 hepatocellular carcinoma patients after curative resection. Corona enhancement, peritumoral hypointensity on HBP, and satellite nodule were identified as significant MRI predictors for early recurrence. These findings can help stratify the risk of early recurrence in at-risk LR-5 HCC patients.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mao-Tong Liu, Ji-Yun Zhang, Lei Xu, Qi Qu, Meng-Tian Lu, Ji-Feng Jiang, Xian-Ce Zhao, Xue-Qin Zhang, Tao Zhang
Summary: The diagnostic value of liver imaging reporting and data system (LI-RADS) v2018 and other imaging features in dual-phenotype hepatocellular carcinoma (DPHCC) was investigated in this study. A pre-diagnostic model based on gadoxetic acid-enhanced MRI was established. Rim arterial phase hyperenhancement and targetoid restriction were found to be independent risk factors for DPHCC. Furthermore, DPHCC, microvascular invasion, tumor diameter, and an increase of alpha-fetoprotein were identified as independent factors for recurrence.
Article
Oncology
Yubo Li, Xiaoyan Ni, Xinai Liu, Chun Yang, Yi Wang, Xin Lu, Changwu Zhou
Summary: The prognostic value of LI-RADS 2018 in differentiating hepatocellular carcinoma from other primary liver cancers with cirrhosis is evaluated in this study. The study retrospectively evaluated 432 patients with cirrhosis and surgically proven single primary liver cancer, and found that LI-RADS categories and tumor size are independent predictors of prognosis. Certain pathological features of liver cancer are also associated with prognosis. LI-RADS categories can independently predict the postsurgical prognosis of primary liver cancer.
JOURNAL OF HEPATOCELLULAR CARCINOMA
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Na Eun Oh, Sang Hyun Choi, Sehee Kim, Habeen Lee, Hyeon Ji Jang, Jae Ho Byun, Hyung Jin Won, Yong Moon Shin
Summary: The diagnostic performance of LI-RADS v2018 on gadoxetic acid-enhanced MRI was evaluated in this study for the detection of hepatocellular carcinoma (HCC). Liver transplant candidates (LT group) were compared with patients who underwent surgical resection (SR group). It was found that LI-RADS v2018 may be insufficient in liver transplant candidates, and other diagnostic imaging tests should be considered in patients with smaller lesion size, larger lesion number, and higher Child-Pugh score.
EUROPEAN RADIOLOGY
(2023)
Article
Gastroenterology & Hepatology
Hyungjin Rhee, Eun-Suk Cho, Ji Hae Nahm, Mi Jang, Yong Eun Chung, Song-Ee Baek, Sunyoung Lee, Myeong-Jin Kim, Mi-Suk Park, Dai Hoon Han, Jin-Young Choi, Young Nyun Park
Summary: This study aimed to characterize MTM-HCC on gadoxetic acid-enhanced MRI and evaluate the diagnostic accuracy and prognostic value of these imaging characteristics. Two diagnostic criteria were developed for MTM-HCC based on MRI findings which showed good sensitivity and specificity, and were associated with poor outcomes after hepatic resection.
JOURNAL OF HEPATOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ji Yoon Moon, Ji Hye Min, Young Kon Kim, Donglk Cha, Jeong Ah Hwang, Seong Eun Ko, Seo-Youn Choi, Eun Joo Yun, Seon Woo Kim, Ho-Jeong Won
Summary: The MRI features of hepatocellular carcinoma patients, especially those with targetoid appearance and rim arterial-phase hyperenhancement based on LI-RADS, are closely associated with prognosis. Additionally, tumor size is a key factor affecting patient outcomes. These findings can help doctors better predict postoperative prognosis for patients.
KOREAN JOURNAL OF RADIOLOGY
(2021)
Article
Oncology
Ruofan Sheng, Jing Huang, Weiguo Zhang, Kaipu Jin, Li Yang, Huanhuan Chong, Jia Fan, Jian Zhou, Dijia Wu, Mengsu Zeng
Summary: This study developed a semi-automatic expert-guided LI-RADS grading system based on deep learning for identifying LR-3 to 5 lesions on multiphase gadoxetic acid-enhanced MRI. The system demonstrated higher accuracy and superiority in HCC diagnosis, suggesting improved workflow efficiency in clinical practice.
JOURNAL OF HEPATOCELLULAR CARCINOMA
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jianmin Ding, Lei Long, Xiang Zhang, Chen Chen, Hongyu Zhou, Yan Zhou, Yandong Wang, Xiang Jing, Zhaoxiang Ye, Fengmei Wang
Summary: This study compared the classification of liver nodules in high-risk hepatocellular carcinoma patients using CEUS and CECT/MRI LI-RADS, finding fair inter-modality agreement and comparable positive predictive values for HCC. CECT/MRI showed better diagnostic performance for non-HCC malignancy compared to CEUS.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jie Yang, Jia-Yan Huang, Xing Chen, Wen-Wu Ling, Yan Luo, Yu-Jun Shi, Ji-Bin Liu, Qiang Lu, Andrej Lyshchik
Summary: The study evaluated the relationship between CEUS LI-RADS classification of cHCC-CCA and their histopathological component predominance, as well as the prediction of patient survival post-surgical resection. LR-5 category tended to represent HCC-predominant tumors with longer disease-free survival compared to LR-M and LR-TIV categories in cHCC-CCA patients.
EUROPEAN RADIOLOGY
(2021)
Article
Oncology
Xinai Liu, Xiaoyan Ni, Yubo Li, Chun Yang, Yi Wang, Chunzheng Ma, Changwu Zhou, Xin Lu
Summary: The study evaluated the diagnostic performance of LI-RADS version 2018 in differentiating hepatocellular carcinoma and other primary liver cancers in patients with liver cirrhosis based on the updated 2019 WHO classification. The study found that LR-5 and LR-M categories had good sensitivity and specificity in distinguishing hepatocellular carcinoma from other primary liver malignancies.
FRONTIERS IN ONCOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Seo Yeon Youn, Dong Hwan Kim, Joon-Il Choi, Moon Hyung Choi, Bohyun Kim, Yu Ri Shin, Soon Nam Oh, Sung Eun Rha
Summary: The study demonstrated that using arterial subtraction images improved the sensitivity while maintaining specificity for predicting the viability of hepatocellular carcinoma after locoregional therapy, compared to ordinary arterial-phase images.
KOREAN JOURNAL OF RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ji Hye Min, Min Woo Lee, Hee Sun Park, Dong Ho Lee, Hyun Jeong Park, Ji Eun Lee, Sae-Jin Park, Seung-Seob Kim, Seung Hyun Park, Sang Yun Ha, Jeong Ah Hwang, Dong Ik Cha, Boram Park
Summary: Interobserver variation exists in LI-RADS targetoid appearances among radiologists, and requiring multiple targetoid appearances improves the diagnostic accuracy for non-HCC malignancy.
AMERICAN JOURNAL OF ROENTGENOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Subin Heo, Sang Hyun Choi, Sun Hong, Dong Wook Kim
Summary: This study investigates the association between the visualization score of gadoxetic acid-enhanced MRI and clinical factors, and evaluates its effect on the diagnostic accuracy for HCC <= 3.0 cm.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Gastroenterology & Hepatology
Seung Baek Hong, Sun Hong, Sang Hyun Choi, Seo Young Park, Ju Hyun Shim, So Yeon Kim, Seung Soo Lee, Suk Kim
Summary: This study found that gadoxetic acid-enhanced multiple arterial-phase magnetic resonance imaging (MA-MRI) can improve the sensitivity for diagnosing hepatocellular carcinoma (HCC) <= 3.0 cm compared to single arterial-phase MRI (SA-MRI), without a significant decrease in specificity.
LIVER INTERNATIONAL
(2023)
Article
Gastroenterology & Hepatology
Hyungjin Rhee, Hyun-Ji Lim, Kyunghwa Han, Suk-Keu Yeom, Sang Hyun Choi, Ji Hoon Park, Eun-Suk Cho, Sumi Park, Mi-Jung Lee, Gi Hong Choi, Dai Hoon Han, Seung Soo Lee, Mi-Suk Park
Summary: A simple scoring system was developed to predict lymph node metastasis in patients with intrahepatic cholangiocarcinoma. The score, based on MRI and clinical findings, was associated with lymph node metastasis and outperformed MRI-suspicious LN alone in predicting pathological LN lesions.
HEPATOLOGY INTERNATIONAL
(2023)
Article
Gastroenterology & Hepatology
Se Jin Choi, Sang Hyun Choi, Dong Wook Kim, Jae Ho Byun, Hyung Jin Won, Yong Moon Shin
Summary: This study found a significant association between threshold growth and hepatocellular carcinoma (HCC). Using threshold growth as a major diagnostic feature in LI-RADS v2018 can improve sensitivity in diagnosing HCC.
JOURNAL OF HEPATOLOGY
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Ijin Joo, Jeong Min Lee, Young Hwan Koh, Sang Hyun Choi, Sunyoung Lee, Jin Wook Chung
KOREAN JOURNAL OF RADIOLOGY
(2023)
Article
Gastroenterology & Hepatology
Won-Mook Choi, Seo Yeon Yoo, Jong-In Chang, Seungbong Han, Young Seok Kim, Dong Hyun Sinn, Sang Hyun Choi, Dong Il Gwon, Young-Suk Lim
Summary: This study aimed to develop and validate a prognostic model for identifying patients with a risk of poor short-term survival after PSSE. Results showed that baseline levels of serum albumin, total bilirubin, and international normalized ratio were significantly associated with 1-year overall survival after PSSE. The ABI score, developed based on these factors, showed good discrimination performance in predicting 3-month and 6-month survival.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ji Young Choi, Kyoung Won Kim, Jong Keon Jang, Sang Hyun Choi, Heon-Ju Kwon, Young -In Yoon, Gi-Won Song, Sung-Gyu Lee
Summary: This study investigated the value of Doppler ultrasonography in predicting clinical outcomes after antirejection treatment for patients with acute cellular rejection (ACR) following liver transplantation (LT). Abnormal PBVearly post-treatment and a decrease between PBVevent and PBVearly post-treatment were significantly associated with poor treatment response in patients with ACR after LT.
Article
Radiology, Nuclear Medicine & Medical Imaging
Woo Kyoung Jeong, Hyo-Jin Kang, Sang Hyun Choi, Mi-Suk Park, Mi Hye Yu, Bohyun Kim, Myung-Won You, Sanghyeok Lim, Young Seo Cho, Min Woo Lee, Jeong Ah Hwang, Jae Young Lee, Jung Hoon Kim, Ijin Joo, Jae Seok Bae, So Yeon Kim, Yong Eun Chung, Dong Hwan Kim, Jeong Min Lee
Summary: Sonazoid, a second-generation ultrasound contrast agent, has been used for the diagnosis of hepatic nodules. To address the diagnostic issues of hepatocellular carcinoma (HCC) with Sonazoid contrast-enhanced ultrasonography, the Korean Society of Radiology and Korean Society of Abdominal Radiology collaborated on evidence-based guidelines, which were selected using an electronic voting system. These guidelines cover imaging protocols, diagnostic criteria, diagnostic value for inconclusive lesions, differentiation from non-HCC malignancies, surveillance of HCC, and treatment response after locoregional and systemic treatment.
KOREAN JOURNAL OF RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Boryeong Jeong, Se Jin Choi, Sang Hyun Choi, Hyeon Ji Jang, Jae Ho Byun, Hyung Jin Won, Yong Moon Shin
Summary: This study compared the accuracy of LI-RADS based on original threshold growth (TG) and LI-RADS based on tumor growth rate for the diagnosis of HCC. It was found that LI-RADS based on tumor growth rate showed higher diagnostic accuracy for HCC.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Na Eun Oh, Sang Hyun Choi, Sehee Kim, Habeen Lee, Hyeon Ji Jang, Jae Ho Byun, Hyung Jin Won, Yong Moon Shin
Summary: The diagnostic performance of LI-RADS v2018 on gadoxetic acid-enhanced MRI was evaluated in this study for the detection of hepatocellular carcinoma (HCC). Liver transplant candidates (LT group) were compared with patients who underwent surgical resection (SR group). It was found that LI-RADS v2018 may be insufficient in liver transplant candidates, and other diagnostic imaging tests should be considered in patients with smaller lesion size, larger lesion number, and higher Child-Pugh score.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hyeon Ji Jang, Sang Hyun Choi, Se Jin Choi, Won-Mook Choi, Jae Ho Byun, Hyung Jin Won, Yong Moon Shin
Summary: This study aimed to develop and evaluate a modified LI-RADS version 2018 for diagnosing hepatocellular carcinoma (HCC) < 1.0 cm. Significant ancillary features associated with HCC < 1.0 cm were determined and applied to the modified LI-RADS. The sensitivity of our modified LI-RADS using restricted diffusion was significantly higher than LI-RADS v2018, with similar specificity.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ji Young Choi, Jihye Yun, Subin Heo, Dong Wook Kim, Sang Hyun Choi, Jiyoung Yoon, Kyuwon Kim, Kee Wook Jung, Seung-Jae Myung
Summary: The quantitative motility score calculated from cine MRI enables diagnosis of an adynamic small bowel and potentially discerns various degrees of bowel motility.
KOREAN JOURNAL OF RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Subin Heo, Hyo Jeong Kang, Sang Hyun Choi, Sehee Kim, Youngeun Yoo, Won-Mook Choi, So Yeon Kim, Seung Soo Lee
Summary: This multi-reader study demonstrated that the percentage of LR-M was significantly higher in proliferative HCCs. CT/MRI LR-M was significantly associated with poor overall survival (OS) and recurrence-free survival (RFS), regardless of the pathological classification of proliferative vs. non-proliferative HCCs.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hyo Jung Park, Hyoung Jung Kim, Jung Hoon Kim, So Yeon Kim, Sang Hyun Choi, Jae Ho Byun, Song Cheol Kim, Hee Sang Hwang, Seung-Mo Hong
Summary: This study aimed to evaluate the prognostic value of tumor-to-parenchymal contrast enhancement ratio on portal venous-phase CT (CER on PVP) in pancreatic neuroendocrine neoplasms (PanNENs) and compare its predictive performance with current grading and staging systems. The results showed that CER on PVP had superior predictive performance on postoperative survival compared to the current grading and staging systems, suggesting its potential as a noninvasive preoperative prognostic tool.
EUROPEAN RADIOLOGY
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Eun Joo Park, Jung Hee Son, Sang Hyun Choi
Summary: This study aimed to investigate the imaging features of hepatocellular carcinoma (HCC) in patients with non-alcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) through a systematic review and meta-analysis. The results showed that the frequency of arterial-phase hyperenhancement (APHE) in NAFLD and NASH patients was similar to HCC with other etiology. However, the frequency of washout and enhancing capsule was relatively low in NAFLD and NASH patients. MRI demonstrated similar percentages of APHE and washout compared to CT, but a higher percentage of enhancing capsule.
ABDOMINAL RADIOLOGY
(2022)