Hydroxychloroquine reverses the prothrombotic state in a mouse model of antiphospholipid syndrome: Role of reduced inflammation and endothelial dysfunction

Antiphospholipid antibodies induce thrombosis by PP2A activation via apoER2-Dab2-SHC1 complex formation in endothelium

(2018) Anastasia Sacharidou et al.   BLOOD

Development of a thrombin generation test in cultured endothelial cells: Evaluation of the prothrombotic effects of antiphospholipid antibodies

(2018) Paul Billoir et al.   THROMBOSIS RESEARCH

Attenuation of antimalarial agent hydroxychloroquine on TNF-α-induced endothelial inflammation

(2018) Ruiru Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Antiphospholipid antibody-induced cellular responses depend on epitope specificity : implications for treatment of antiphospholipid syndrome

(2017) N. Müller-Calleja et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The effect of hydroxychloroquine on haemostasis, complement, inflammation and angiogenesis in patients with antiphospholipid antibodies

(2017) Karen Schreiber et al.   RHEUMATOLOGY

Hydroxychloroquine inhibits proinflammatory signalling pathways by targeting endosomal NADPH oxidase

(2016) Nadine Müller-Calleja et al.   ANNALS OF THE RHEUMATIC DISEASES

Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised, controlled, open-label, phase 2/3, non-inferiority trial

(2016) Hannah Cohen et al.   Lancet Haematology

Thrombin generation and factor X assays for the assessment of warfarin anticoagulation in thrombotic antiphospholipid syndrome

(2015) Maria Efthymiou et al.   THROMBOSIS RESEARCH

Infliximab improves endothelial dysfunction in a mouse model of antiphospholipid syndrome: Role of reduced oxidative stress

(2015) Ygal Benhamou et al.   VASCULAR PHARMACOLOGY

Endosomal NADPH-oxidase is critical for induction of the tissue factor gene in monocytes and endothelial cells

(2013) Nadine Prinz et al.   THROMBOSIS AND HAEMOSTASIS

Patient-derived monoclonal antibodies directed towards beta2 glycoprotein-1 display lupus anticoagulant activity

(2011) I. DIENAVA-VERDOOLD et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Antiphospholipid antibodies promote leukocyte–endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via β2GPI and apoER2

(2010) Sangeetha Ramesh et al.   JOURNAL OF CLINICAL INVESTIGATION

Hydroxychloroquine protects the annexin A5 anticoagulant shield from disruption by antiphospholipid antibodies: evidence for a novel effect for an old antimalarial drug

(2009) J. H. Rand et al.   BLOOD

Vascular Abnormalities, Paraoxonase Activity, and Dysfunctional HDL in Primary Antiphospholipid Syndrome

(2009) Marietta Charakida   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Thrombin generation testing in routine clinical practice: are we there yet?

(2008) J. J. van Veen et al.   BRITISH JOURNAL OF HAEMATOLOGY

Tissue factor in the antiphospholipid syndrome

(2008) AV Kinev et al.   LUPUS

Interaction of inflammation, thrombosis, aspirin and enoxaparin in CNS experimental antiphospholipid syndrome

(2008) David Tanne et al.   NEUROBIOLOGY OF DISEASE