Enhanced IL-1β production is mediated by a TLR2-MYD88-NLRP3 signaling axis during coinfection with influenza A virus and Streptococcus pneumoniae

IL-1 Signaling Prevents Alveolar Macrophage Depletion during Influenza andStreptococcus pneumoniaeCoinfection

(2018) Shruti Bansal et al.   JOURNAL OF IMMUNOLOGY

Effects of Influenza on Alveolar Macrophage Viability Are Dependent on Mouse Genetic Strain

(2018) Danielle Califano et al.   JOURNAL OF IMMUNOLOGY

Influenza virus infections among patients attending emergency department according to main reason to presenting to ED: A 3-year prospective observational study during seasonal epidemic periods

(2017) Enrique Casalino et al.   PLoS One

A Critical, Nonlinear Threshold Dictates Bacterial Invasion and Initial Kinetics During Influenza

(2016) Amber M. Smith et al.   Scientific Reports

Influenza-induced type I interferon enhances susceptibility to gram-negative and gram-positive bacterial pneumonia in mice

(2015) Benjamin Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

The immunology of influenza virus-associated bacterial pneumonia

(2015) Keven M Robinson et al.   CURRENT OPINION IN IMMUNOLOGY

Influenza and Bacterial Superinfection: Illuminating the Immunologic Mechanisms of Disease

(2015) Agnieszka Rynda-Apple et al.   INFECTION AND IMMUNITY

Dynamics of Increasing IFN-γ Exposure on Murine MH-S Cell-Line Alveolar Macrophage Phagocytosis ofStreptococcus pneumoniae

(2015) Michael J. Mina et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Type I Interferon Signaling Regulates Activation of the Absent in Melanoma 2 Inflammasome during Streptococcus pneumoniae Infection

(2014) R. Fang et al.   INFECTION AND IMMUNITY

The co-pathogenesis of influenza viruses with bacteria in the lung

(2014) Jonathan A. McCullers   NATURE REVIEWS MICROBIOLOGY

Depletion of Alveolar Macrophages during Influenza Infection Facilitates Bacterial Superinfections

(2013) H. E. Ghoneim et al.   JOURNAL OF IMMUNOLOGY

Immune Dysfunction and Bacterial Coinfections following Influenza

(2013) D. W. Metzger et al.   JOURNAL OF IMMUNOLOGY

Influenza A Exacerbates Staphylococcus aureus Pneumonia by Attenuating IL-1  Production in Mice

(2013) K. M. Robinson et al.   JOURNAL OF IMMUNOLOGY

Complications and Associated Bacterial Coinfections Among Children Hospitalized With Seasonal or Pandemic Influenza, United States, 2003–2010

(2013) Fatimah S. Dawood, Sandra S. Chaves, Alejandro Pérez, Arthur Reingold, James Meek, Monica M. Farley, Patricia Ryan, Ruth Lynfield, Craig Morin, Joan Baumbach, Nancy M. Bennett, Shelley Zansky, Ann Thomas, Mary Lou Lindegren et al.   JOURNAL OF INFECTIOUS DISEASES

Adjunctive Corticosteroid Therapy Improves Lung Immunopathology and Survival During Severe Secondary Pneumococcal Pneumonia in Mice

(2013) H. E. Ghoneim et al.   JOURNAL OF INFECTIOUS DISEASES

Receptor interacting protein kinase 2–mediated mitophagy regulates inflammasome activation during virus infection

(2013) Christopher Lupfer et al.   NATURE IMMUNOLOGY

Kinetics of Coinfection with Influenza A Virus and Streptococcus pneumoniae

(2013) Amber M. Smith et al.   PLoS Pathogens

Early Use of Glucocorticoids Was a Risk Factor for Critical Disease and Death From pH1N1 Infection

(2011) K. Han et al.   CLINICAL INFECTIOUS DISEASES

Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice

(2011) Shigeki Nakamura et al.   JOURNAL OF CLINICAL INVESTIGATION

Critical Roles of ASC Inflammasomes in Caspase-1 Activation and Host Innate Resistance to Streptococcus pneumoniae Infection

(2011) R. Fang et al.   JOURNAL OF IMMUNOLOGY

Influenza A Inhibits Th17-Mediated Host Defense against Bacterial Pneumonia in Mice

(2010) A. Kudva et al.   JOURNAL OF IMMUNOLOGY

Influenza virus activates inflammasomes via its intracellular M2 ion channel

(2010) Takeshi Ichinohe et al.   NATURE IMMUNOLOGY

Influenza Virus Infection Decreases Tracheal Mucociliary Velocity and Clearance ofStreptococcus pneumoniae

(2009) Lynnelle A. Pittet et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

(2009) Irving C. Allen et al.   IMMUNITY

The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1

(2009) Paul G. Thomas et al.   IMMUNITY

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

(2009) Mohamed Lamkanfi et al.   JOURNAL OF CELL BIOLOGY

Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice

(2009) Arash Shahangian et al.   JOURNAL OF CLINICAL INVESTIGATION

Inflammasome recognition of influenza virus is essential for adaptive immune responses

(2009) Takeshi Ichinohe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers

(2008) Christopher Lupfer et al.   ARCHIVES OF VIROLOGY

Predominant Role of Bacterial Pneumonia as a Cause of Death in Pandemic Influenza: Implications for Pandemic Influenza Preparedness

(2008) David M. Morens et al.   JOURNAL OF INFECTIOUS DISEASES

Inhibition of pulmonary antibacterial defense by interferon-γ during recovery from influenza infection

(2008) Keer Sun et al.   NATURE MEDICINE