Article
Public, Environmental & Occupational Health
Y. Zhang, K. Wang, H. Yu, T. Zhaoa, L. Lin, X. Qin, T. Wua, D. Chen, Y. Hua, Y. Wu
Summary: This study aimed to estimate the incidence and characteristics of aspiration pneumonia (AP) in Beijing, China. A historical cohort study was conducted using medical claim records. The results showed that the incidence of AP and pneumonia with risk factors for aspiration (PRFA) increased with age and patients with AP and PRFA had a higher burden of comorbidities compared to community-acquired pneumonia (CAP) patients. The 6-month and 1-year all-cause mortality rates were also higher for AP and PRFA patients compared to CAP patients. This study provides important baseline information for the prevention of AP.
Review
Medicine, General & Internal
Aamer Imdad, Alice G. Wang, Vaishali Adlakha, Natalie M. Crespo, Jill Merrow, Abigail Smith, Olivia Tsistinas, Emily Tanner-Smith, Rachel Rosen
Summary: This study conducted a systematic review and meta-analysis to assess the risk of aspiration pneumonia in children with laryngeal penetration or tracheal aspiration. The results showed that laryngeal penetration may be associated with aspiration pneumonia, but the evidence was not conclusive. On the other hand, tracheal aspiration was found to be significantly associated with aspiration pneumonia. Further research with clear definitions and comprehensive measurements is needed to fully understand the association between laryngeal penetration and aspiration pneumonia.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Dirk Bandorski, Khodr Tello, Harun Erdal, Janine Sommerlad, Jochen Wilhelm, Istvan Vadasz, Matthias Hecker, Dieter Walmrath, Werner Seeger, Ekaterina Krauss, Stefan Kuhnert
Summary: This study evaluates the diagnostic value of gastric biomarkers, such as pepsin and bile acid, in detecting aspiration in the intensive care unit (ICU). The results indicate that measuring pepsin and bile acid does not reliably diagnose aspiration or significantly impact survival outcomes. Further validation studies are needed to assess the clinical usefulness and reliability of these biomarkers in diagnosing aspiration-related conditions.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Agriculture, Dairy & Animal Science
Suzanne Suk Kwan Tso, Ellie Leister, Claire Rebecca Sharp, Jane Heller, Justine S. Gibson
Summary: This study describes the clinical course, culture and susceptibility profiles of dogs and cats mechanically ventilated for tick paralysis. The majority of these cases had concurrent evidence of aspiration pneumonia. Appropriate use of antimicrobials improved outcome. Clinicians should be aware of the development of bacterial pneumonia and select antimicrobials based on culture and susceptibility testing.
Article
Clinical Neurology
Bendix Labeit, Thalia Grond, Achim G. Beule, Maik Boehmer, Christian Thomas, Paul Muhle, Inga Claus, Malte Roderigo, Claudia Rudack, Heinz Wiendl, Rainer Dziewas, Tobias Warnecke, Sonja Suntrup-Krueger
Summary: The specific diagnostic algorithm presented in this study helps identify patients with an IIM-compatible dysphagia pattern and provides further IIM-focused diagnostic and therapeutic procedures. Treatment of patients diagnosed with IIM resulted in improvement of dysphagia in some cases post-therapy.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Multidisciplinary Sciences
Jun Hee Won, Seong Jun Byun, Byung-Mo Oh, Sang Jun Park, Han Gil Seo
Summary: Patients with Parkinson's disease are at an increased risk for aspiration pneumonia, with approximately two-thirds of patients dying within a year after experiencing it. Further studies are needed to prevent aspiration pneumonia and implement effective treatments to reduce mortality in PD patients.
SCIENTIFIC REPORTS
(2021)
Article
Oncology
Siyuan Yao, Ryosuke Kita, Kana Ishikawa, Takashi Kumode, Keisuke Tanino, Ryosuke Mizuno, Yugo Matsui, Shusaku Honma, Teppei Murakami, Takatsugu Kan, Sanae Nakajima, Satoshi Kaihara, Takehisa Harada
Summary: Gastrojejunostomy (GJ) may not be the optimal choice for very elderly patients, especially those with gastric cancer, as it is associated with a higher incidence of surgical complications. Age ≥ 80 years is identified as an independent predictor of delayed gastric emptying (DGE) and survival after GJ. Antiperistaltic anastomosis with partial stomach partitioning (PSP) has the lowest occurrence rate of DGE and aspiration pneumonia.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Infectious Diseases
Hideo Kato, Mao Hagihara, Yoshihiko Morikawa, Nobuhiro Asai, Hiroshige Mikamo, Takuya Iwamoto
Summary: This study retrospectively evaluated the effectiveness and safety of ceftriaxone administered twice daily with a dosage of 1 g versus ceftriaxone administered once daily with a dosage of 2 g for the treatment of aspiration pneumonia. The results showed that the once daily administration of 2 g ceftriaxone had significantly improved clinical responses compared to the twice daily administration of 1 g. The incidence of choleliths during ceftriaxone therapy was also found to be lower in the once daily administration group.
Article
Veterinary Sciences
Jonathan D. Dear, William Vernau, Eric G. Johnson, Sean E. Hulsebosch, Lynelle R. Johnson
Summary: This study examined cats with aspiration pneumonia and bronchopneumonia, finding that cats with AP were less likely to present with cough, more likely to be hypothermic, and had a shorter duration of signs compared to cats with BP or IAD. Radiographically, cats with AP were more likely to exhibit an alveolar pattern and higher total score than cats with BP or IAD.
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2021)
Article
Critical Care Medicine
Judith Marin-Corral, Sergi Pascual-Guardia, Francesco Amati, Stefano Aliberti, Joan R. Masclans, Nilam Soni, Alejandro Rodriguez, Oriol Sibila, Francisco Sanz, Giovanni Sotgiu, Antonio Anzueto, Katerina Dimakou, Roberta Petrino, Ewoudt van de Garde, Marcos I. Restrepo
Summary: This study analyzed aspiration risk factors, microbiology patterns, and empiric anti-anaerobic use in patients hospitalized with CAP. Results showed that patients with ACAP or CAP/AspRF+ had similar anaerobic flora compared with those without aspiration risk factors, and Gram-negative bacteria were more prevalent in severe ACAP patients. Despite similar microbiological flora between groups, a large proportion of CAP patients received anti-anaerobic antibiotic coverage.
Review
Respiratory System
Rumi Ueha, Redentor B. Magdayao, Misaki Koyama, Taku Sato, Takao Goto, Tatsuya Yamasoba
Summary: Severe dysphagia can lead to life-threatening conditions such as intractable pneumonia. Surgical intervention is necessary to prevent intractable aspiration and its complications. This review aims to increase awareness among medical professionals about aspiration prevention surgeries and guide the selection of appropriate surgical options.
RESPIRATORY RESEARCH
(2023)
Article
Geriatrics & Gerontology
J. Ahn, J. S. Chang, J. W. Kim
Summary: This study investigated the incidence of postoperative pneumonia and aspiration pneumonia after hip fracture surgery, finding rates of 3.9% and 1.7% respectively. Significant risk factors included postoperative delirium and preoperative serum albumin levels.
JOURNAL OF NUTRITION HEALTH & AGING
(2022)
Article
Geriatrics & Gerontology
Alain Putot, Sophie Putot, Patrick Manckoundia
Summary: This study evaluated the short- and long-term prognosis after aspiration pneumonia (AsP) in older inpatients and found that AsP patients had significantly higher mortality rates. However, among those who survived 30 days, long-term mortality did not significantly differ from patients with other causes of pneumonia. These findings emphasize the importance of early management of AsP.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2023)
Article
Multidisciplinary Sciences
Kosaku Komiya, Takashi Yamamoto, Hiroki Yoshikawa, Akihiko Goto, Kenji Umeki, Takeshi Johkoh, Kazufumi Hiramatsu, Jun-ichi Kadota
Summary: This study found that factors such as impaired consciousness, daily living activities, hemoglobin levels, and sex were associated with the gravity-dependent distribution of aspiration pneumonia on chest images. However, this distribution did not affect disease prognosis or in-hospital mortality. Impaired consciousness was identified as the most significant predictor of aspiration pneumonia.
SCIENTIFIC REPORTS
(2022)
Article
Health Care Sciences & Services
Min Cheol Chang, Ho Yong Choi, Donghwi Park
Summary: This study evaluated the usefulness of the modified videofluoroscopic dysphagia scale (mVDS) in determining whether to allow oral feeding in patients with dysphagia due to deconditioning or frailty. The results showed a significant association between the mVDS total score and oral feeding methods, as well as a correlation between mVDS and the presence of aspiration pneumonia.