Dynasore Suppresses mTORC1 Activity and Induces Autophagy to Regulate the Clearance of Protein Aggregates in Neurodegenerative Diseases

Mechanism and medical implications of mammalian autophagy

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H6, a novel hederagenin derivative, reverses multidrug resistance in vitro and in vivo

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TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading

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A fluorescence-based imaging method to measure in vitro and in vivo mitophagy using mt-Keima

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Lx2-32c, a novel semi-synthetic taxane, exerts antitumor activity against prostate cancer cells in vitro and in vivo

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Dihydromyricetin protects neurons in an MPTP-induced model of Parkinson's disease by suppressing glycogen synthase kinase-3 beta activity

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Dynasore - not just a dynamin inhibitor

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TDP-43 loss of function increases TFEB activity and blocks autophagosome-lysosome fusion

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Starvation-induced MTMR13 and RAB21 activity regulates VAMP8 to promote autophagosome-lysosome fusion

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Nucleolar stress and impaired stress granule formation contribute to C9orf72 RAN translation-induced cytotoxicity

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The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease

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Rag GTPases mediate amino acid–dependent recruitment of TFEB and MITF to lysosomes

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The regulation of N-terminal Huntingtin (Htt552) accumulation by Beclin1

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MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB

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mTOR Signaling in Growth Control and Disease

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Ataxin-3 Regulates Aggresome Formation of Copper-Zinc Superoxide Dismutase (SOD1) by Editing K63-linked Polyubiquitin Chains

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The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis

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PGC-1  Rescues Huntington's Disease Proteotoxicity by Preventing Oxidative Stress and Promoting TFEB Function

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The Endoplasmic Reticulum (ER)-associated Degradation System Regulates Aggregation and Degradation of Mutant Neuroserpin

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TFEB Links Autophagy to Lysosomal Biogenesis

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Autophagy gone awry in neurodegenerative diseases

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mTOR: from growth signal integration to cancer, diabetes and ageing

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Gp78, an ER associated E3, promotes SOD1 and ataxin-3 degradation

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A Gene Network Regulating Lysosomal Biogenesis and Function

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

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