Environmental enrichment, new neurons and the neurobiology of individuality

Human Hippocampal Neurogenesis Persists throughout Aging

(2018) Maura Boldrini et al.   Cell Stem Cell

Human Adult Neurogenesis: Evidence and Remaining Questions

(2018) Gerd Kempermann et al.   Cell Stem Cell

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

(2018) Shawn F. Sorrells et al.   NATURE

Environmental enrichment effects on synaptic and cellular physiology of hippocampal neurons

(2018) S.M. Ohline et al.   NEUROPHARMACOLOGY

The Neuroprotective Effects of Experience on Cognitive Functions: Evidence from Animal Studies on the Neurobiological Bases of Brain Reserve

(2018) Francesca Gelfo et al.   NEUROSCIENCE

News Feature: What happens when lab animals go wild

(2018) Carolyn Beans   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Environmental enrichment increases transcriptional and epigenetic differentiation between mouse dorsal and ventral dentate gyrus

(2018) Tie-Yuan Zhang et al.   Nature Communications

Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data

(2018) Viola André et al.   PLOS BIOLOGY

Hippocampal neurogenesis confers stress resilience by inhibiting the ventral dentate gyrus

(2018) Christoph Anacker et al.   NATURE

The impact of environmental interventions among mouse siblings on the heritability and malleability of general cognitive ability

(2018) Bruno Sauce et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Social interactions impact on the dopaminergic system and drive individuality

(2018) N. Torquet et al.   Nature Communications

Exposure to complex environments results in more sparse representations of space in the hippocampus

(2017) David K. Bilkey et al.   HIPPOCAMPUS

Active Dentate Granule Cells Encode Experience to Promote the Addition of Adult-Born Hippocampal Neurons

(2017) Gregory W. Kirschen et al.   JOURNAL OF NEUROSCIENCE

Adult Hippocampal Neurogenesis along the Dorsoventral Axis Contributes Differentially to Environmental Enrichment Combined with Voluntary Exercise in Alleviating Chronic Inflammatory Pain in Mice

(2017) Jie Zheng et al.   JOURNAL OF NEUROSCIENCE

Enriched environment effects on remote object recognition memory

(2017) Riccardo Melani et al.   NEUROSCIENCE

Paternal environmental enrichment transgenerationally alters affective behavioral and neuroendocrine phenotypes

(2017) Shlomo Yeshurun et al.   PSYCHONEUROENDOCRINOLOGY

The comparative immunology of wild and laboratory mice, Mus musculus domesticus

(2017) Stephen Abolins et al.   Nature Communications

Differential Roles of Environmental Enrichment in Alzheimer’s Type of Neurodegeneration and Physiological Aging

(2017) Vladimir V. Salmin et al.   Frontiers in Aging Neuroscience

Effects of Environmental Enrichment on Doublecortin and BDNF Expression along the Dorso-Ventral Axis of the Dentate Gyrus

(2017) Fabio Gualtieri et al.   Frontiers in Neuroscience

Cynefin as Reference Framework to Facilitate Insight and Decision-Making in Complex Contexts of Biomedical Research

(2017) Gerd Kempermann   Frontiers in Neuroscience

Transgenerational effects of environmental enrichment on repetitive motor behavior development

(2016) Allison R. Bechard et al.   BEHAVIOURAL BRAIN RESEARCH

The neurogenic effects of an enriched environment and its protection against the behavioral consequences of chronic mild stress persistent after enrichment cessation in six-month-old female Balb/C mice

(2016) Nelly Maritza Vega-Rivera et al.   BEHAVIOURAL BRAIN RESEARCH

Limited Effects of Prolonged Environmental Enrichment on the Pathology of 5XFAD Mice

(2016) Melanie Hüttenrauch et al.   MOLECULAR NEUROBIOLOGY

Convergent transcriptomics and proteomics of environmental enrichment and cocaine identifies novel therapeutic strategies for addiction

(2016) Yafang Zhang et al.   NEUROSCIENCE

Nuclear RNA-seq of single neurons reveals molecular signatures of activation

(2016) Benjamin Lacar et al.   Nature Communications

Alzheimer's Disease and Hippocampal Adult Neurogenesis; Exploring Shared Mechanisms

(2016) Carolyn Hollands et al.   Frontiers in Neuroscience

Impact of Enriched Environment on Murine T Cell Differentiation and Gene Expression Profile

(2016) Lorenza Rattazzi et al.   Frontiers in Immunology

Mice in an enriched environment learn more flexibly because of adult hippocampal neurogenesis

(2015) Alexander Garthe et al.   HIPPOCAMPUS

Interactive actions of Bdnf methylation and cell metabolism for building neural resilience under the influence of diet

(2015) Ethika Tyagi et al.   NEUROBIOLOGY OF DISEASE

Association between exploratory activity and social individuality in genetically identical mice living in the same enriched environment

(2015) J. Freund et al.   NEUROSCIENCE

Only watching others making their experiences is insufficient to enhance adult neurogenesis and water maze performance in mice

(2015) Deetje Iggena et al.   Scientific Reports

Environmental Enrichment Reduces Anxiety by Differentially Activating Serotonergic and Neuropeptide Y (NPY)-Ergic System in Indian Field Mouse (Mus booduga): An Animal Model of Post-Traumatic Stress Disorder

(2015) Durairaj Ragu Varman et al.   PLoS One

Neurogenesis in the Striatum of the Adult Human Brain

(2014) Aurélie Ernst et al.   CELL

Promoting Neurological Recovery in the Post-Acute Stroke Phase: Benefits and Challenges

(2014) Dirk M. Hermann et al.   EUROPEAN NEUROLOGY

Spine morphogenesis in newborn granule cells is differentially regulated in the outer and middle molecular layers

(2014) Chunmei Zhao et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Potential for primary prevention of Alzheimer's disease: an analysis of population-based data

(2014) Sam Norton et al.   LANCET NEUROLOGY

Cellular and molecular mechanisms of immunomodulation in the brain through environmental enrichment

(2014) Gaurav Singhal et al.   Frontiers in Cellular Neuroscience

Mapping ecologically relevant social behaviours by gene knockout in wild mice

(2014) Lea Chalfin et al.   Nature Communications

Enrichment-induced exercise to quantify the effect of different housing conditions: A tool to standardize enriched environment protocols

(2013) Hongyu Xie et al.   BEHAVIOURAL BRAIN RESEARCH

Dynamics of Hippocampal Neurogenesis in Adult Humans

(2013) Kirsty L. Spalding et al.   CELL

Region-dependent and stage-specific effects of stress, environmental enrichment, and antidepressant treatment on hippocampal neurogenesis

(2013) Arnaud Tanti et al.   HIPPOCAMPUS

Enriched Environments and Motor Outcomes in Cerebral Palsy: Systematic Review and Meta-analysis

(2013) C. Morgan et al.   PEDIATRICS

Standardized Environmental Enrichment Supports Enhanced Brain Plasticity in Healthy Rats and Prevents Cognitive Impairment in Epileptic Rats

(2013) Raafat P. Fares et al.   PLoS One

Emergence of Individuality in Genetically Identical Mice

(2013) J. Freund et al.   SCIENCE

Unique Processing During a Period of High Excitation/Inhibition Balance in Adult-Born Neurons

(2012) Antonia Marín-Burgin et al.   SCIENCE

Seven principles in the regulation of adult neurogenesis

(2011) Gerd Kempermann   EUROPEAN JOURNAL OF NEUROSCIENCE

Running is the neurogenic and neurotrophic stimulus in environmental enrichment

(2011) T. Kobilo et al.   LEARNING & MEMORY

Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation

(2011) Amar Sahay et al.   NATURE

Genetics and human agency: Comment on Dar-Nimrod and Heine (2011).

(2011) Eric Turkheimer   PSYCHOLOGICAL BULLETIN

Effects of environmental enrichment and voluntary exercise on neurogenesis, learning and memory, and pattern separation: BDNF as a critical variable?

(2011) Pedro Bekinschtein et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Long-lasting and transgenerational effects of an environmental enrichment on memory formation

(2010) Junko A. Arai et al.   BRAIN RESEARCH BULLETIN

The anxiolytic effect of environmental enrichment is mediated via amygdalar CRF receptor type 1

(2010) Y Sztainberg et al.   MOLECULAR PSYCHIATRY

Environmental enrichment requires adult neurogenesis to facilitate the recovery from psychosocial stress

(2010) R J Schloesser et al.   MOLECULAR PSYCHIATRY

Murine Features of Neurogenesis in the Human Hippocampus across the Lifespan from 0 to 100 Years

(2010) Rolf Knoth et al.   PLoS One

On whether the environmental enrichment may provide cognitive and brain reserves

(2009) Laura Petrosini et al.   BRAIN RESEARCH REVIEWS

Transgenerational Rescue of a Genetic Defect in Long-Term Potentiation and Memory Formation by Juvenile Enrichment

(2009) J. A. Arai et al.   JOURNAL OF NEUROSCIENCE

Environmental standardization: cure or cause of poor reproducibility in animal experiments?

(2009) S Helene Richter et al.   NATURE METHODS

Maternal enrichment affects prenatal hippocampal proliferation and open-field behaviors in female offspring mice

(2009) Takashi Maruoka et al.   NEUROSCIENCE LETTERS

Adult-Generated Hippocampal Neurons Allow the Flexible Use of Spatially Precise Learning Strategies

(2009) Alexander Garthe et al.   PLoS One

A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation

(2009) C. D. Clelland et al.   SCIENCE

Enrich the environment to empower the brain

(2009) Alessandro Sale et al.   TRENDS IN NEUROSCIENCES

Chronic Fluoxetine Stimulates Maturation and Synaptic Plasticity of Adult-Born Hippocampal Granule Cells

(2008) J.-W. Wang et al.   JOURNAL OF NEUROSCIENCE

Differential 24 h responsiveness of Prox1–expressing precursor cells in adult hippocampal neurogenesis to physical activity, environmental enrichment, and kainic acid–induced seizures

(2008) B. Steiner et al.   NEUROSCIENCE

The neurogenic reserve hypothesis: what is adult hippocampal neurogenesis good for?

(2008) Gerd Kempermann   TRENDS IN NEUROSCIENCES