期刊
NATURE REVIEWS ENDOCRINOLOGY
卷 15, 期 5, 页码 259-260出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/s41574-019-0191-9
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资金
- National Science Foundation of China [81530040, 81771553]
- Excellence in Centers of Clinical Medicine grant from the Science and Technology Commission of Shanghai Municipality [2017ZZ01016]
- Science and Technology Commission of Shanghai Municipality
Jae-Wook Jeong and colleagues report that histone deacetylase 3 (HDAC3) is downregulated in the endometrium of women with endometriosis. In addition, they show that the loss of HDAC3 is associated with aberrant hormonal signalling and increased fibrosis in the endometrium and impaired endometrial receptivity.
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