Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity

Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA

(2018) Tamer Sallam et al.   NATURE MEDICINE

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion

(2016) Sungguan Hong et al.   NATURE MEDICINE

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

(2016) Tuomas O. Kilpeläinen et al.   Nature Communications

Diet-Induced Obese Mice Retain Endogenous Leptin Action

(2015) Nickki Ottaway et al.   Cell Metabolism

Physical activity and the risk of type 2 diabetes: a systematic review and dose–response meta-analysis

(2015) Dagfinn Aune et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Efficient Bayesian mixed-model analysis increases association power in large cohorts

(2015) Po-Ru Loh et al.   NATURE GENETICS

Nuclear Factor-Y is an adipogenic factor that regulates leptin gene expression

(2015) Yi-Hsueh Lu et al.   Molecular Metabolism

Looping Back to Leap Forward: Transcription Enters a New Era

(2014) Michael Levine et al.   CELL

Anti-diabetic rosiglitazone remodels the adipocyte transcriptome by redistributing transcription to PPAR -driven enhancers

(2014) S. E. Step et al.   GENES & DEVELOPMENT

A Long Noncoding RNA Transcriptional Regulatory Circuit Drives Thermogenic Adipocyte Differentiation

(2014) Xu-Yun Zhao et al.   MOLECULAR CELL

Enhancer RNAs and regulated transcriptional programs

(2014) Michael T.Y. Lam et al.   TRENDS IN BIOCHEMICAL SCIENCES

Long noncoding RNAs regulate adipogenesis

(2013) Lei Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Long Noncoding RNA Mediates Both Activation and Repression of Immune Response Genes

(2013) S. Carpenter et al.   SCIENCE

What makes UK Biobank special?

(2012) Rory Collins   LANCET

Conserved Function of lincRNAs in Vertebrate Embryonic Development despite Rapid Sequence Evolution

(2011) Igor Ulitsky et al.   CELL

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Global Mapping of Cell Type–Specific Open Chromatin by FAIRE-seq Reveals the Regulatory Role of the NFI Family in Adipocyte Differentiation

(2011) Hironori Waki et al.   PLoS Genetics

Hyperleptinemia Is Required for the Development of Leptin Resistance

(2010) Zachary A. Knight et al.   PLoS One

Leptin at 14 y of age: an ongoing story

(2009) Jeffrey M Friedman   AMERICAN JOURNAL OF CLINICAL NUTRITION

Long non-coding RNAs: insights into functions

(2009) Tim R. Mercer et al.   NATURE REVIEWS GENETICS

The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome

(2008) Mathieu Firmann et al.   BMC Cardiovascular Disorders

Design and implementation of a high-throughput biological sample processing facility using modern manufacturing principles

(2008) P. Downey et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

The UK Biobank sample handling and storage protocol for the collection, processing and archiving of human blood and urine

(2008) P. Elliott et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

The UK Biobank sample handling and storage validation studies

(2008) T. C Peakman et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY