标题
Opportunities and challenges for transcriptome-wide association studies
作者
关键词
-
出版物
NATURE GENETICS
Volume 51, Issue 4, Pages 592-599
出版商
Springer Nature
发表日期
2019-03-30
DOI
10.1038/s41588-019-0385-z
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Integrating predicted transcriptome from multiple tissues improves association detection
- (2019) Alvaro N. Barbeira et al. PLoS Genetics
- Probabilistic fine-mapping of transcriptome-wide association studies
- (2019) Nicholas Mancuso et al. NATURE GENETICS
- A statistical framework for cross-tissue transcriptome-wide association analysis
- (2019) Yiming Hu et al. NATURE GENETICS
- The Post-GWAS Era: From Association to Function
- (2018) Michael D. Gallagher et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights
- (2018) Alexander Gusev et al. NATURE GENETICS
- Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
- (2018) Hilary K. Finucane et al. NATURE GENETICS
- Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics
- (2018) Alvaro N. Barbeira et al. Nature Communications
- Genetic architecture of gene expression traits across diverse populations
- (2018) Lauren S. Mogil et al. PLoS Genetics
- A Powerful Framework for Integrating eQTL and GWAS Summary Data
- (2017) Zhiyuan Xu et al. GENETICS
- Genetic effects on gene expression across human tissues
- (2017) François Aguet et al. NATURE
- Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7
- (2017) Yang Luo et al. NATURE GENETICS
- Estimating the causal tissues for complex traits and diseases
- (2017) Halit Ongen et al. NATURE GENETICS
- Integrating molecular QTL data into genome-wide genetic association analysis: Probabilistic assessment of enrichment and colocalization
- (2017) Xiaoquan Wen et al. PLoS Genetics
- The Human Cell Atlas
- (2017) Aviv Regev et al. eLife
- A Powerful Framework for Integrating eQTL and GWAS Summary Data
- (2017) Zhiyuan Xu et al. GENETICS
- Colocalization of GWAS and eQTL Signals Detects Target Genes
- (2016) Farhad Hormozdiari et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Local regulation of gene expression by lncRNA promoters, transcription and splicing
- (2016) Jesse M. Engreitz et al. NATURE
- Schizophrenia risk from complex variation of complement component 4
- (2016) Aswin Sekar et al. NATURE
- Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
- (2016) Zhihong Zhu et al. NATURE GENETICS
- Integrative approaches for large-scale transcriptome-wide association studies
- (2016) Alexander Gusev et al. NATURE GENETICS
- The statistical properties of gene-set analysis
- (2016) Christiaan A. de Leeuw et al. NATURE REVIEWS GENETICS
- Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases
- (2016) O. Franzen et al. SCIENCE
- CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells
- (2016) S. John Liu et al. SCIENCE
- Predicting gene targets from integrative analyses of summary data from GWAS and eQTL studies for 28 human complex traits
- (2016) Jennifer M. Whitehead Pavlides et al. Genome Medicine
- Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
- (2015) Jimmy Z Liu et al. NATURE GENETICS
- A gene-based association method for mapping traits using reference transcriptome data
- (2015) Eric R Gamazon et al. NATURE GENETICS
- FTO Obesity Variant Circuitry and Adipocyte Browning in Humans
- (2015) Melina Claussnitzer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Non-coding RNA: what is functional and what is junk?
- (2015) Alexander F. Palazzo et al. Frontiers in Genetics
- Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
- (2014) Claudia Giambartolomei et al. PLoS Genetics
- Sherlock: Detecting Gene-Disease Associations by Matching Patterns of Expression QTL and GWAS
- (2013) Xin He et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Discovery and refinement of loci associated with lipid levels
- (2013) Cristen J Willer et al. NATURE GENETICS
- Pleiotropy in complex traits: challenges and strategies
- (2013) Nadia Solovieff et al. NATURE REVIEWS GENETICS
- Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes
- (2012) Chris Wallace et al. HUMAN MOLECULAR GENETICS
- Mapping cis- and trans-regulatory effects across multiple tissues in twins
- (2012) Elin Grundberg et al. NATURE GENETICS
- Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses
- (2012) Oliver Stegle et al. Nature Protocols
- Rare-Variant Association Testing for Sequencing Data with the Sequence Kernel Association Test
- (2011) Michael C. Wu et al. AMERICAN JOURNAL OF HUMAN GENETICS
- From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
- (2010) Kiran Musunuru et al. NATURE
- Candidate Causal Regulatory Effects by Integration of Expression QTLs with Complex Trait Genetic Associations
- (2010) Alexandra C. Nica et al. PLoS Genetics
- Statistical independence of the colocalized association signals for type 1 diabetes and RPS26 gene expression on chromosome 12q13
- (2008) Vincent Plagnol et al. BIOSTATISTICS
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