Directionality of dynein is controlled by the angle and length of its stalk

Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures

(2017) Elizabeth H. Kellogg et al.   JOURNAL OF MOLECULAR BIOLOGY

Angular measurements of the dynein ring reveal a stepping mechanism dependent on a flexible stalk

(2017) Lisa G. Lippert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Creating biomolecular motors based on dynein and actin-binding proteins

(2016) Akane Furuta et al.   Nature Nanotechnology

Cytoplasmic dynein regulates its attachment to microtubules via nucleotide state-switched mechanosensing at multiple AAA domains

(2015) Matthew P. Nicholas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct observation shows superposition and large scale flexibility within cytoplasmic dynein motors moving along microtubules

(2015) Hiroshi Imai et al.   Nature Communications

Kinesin’s Front Head Is Gated by the Backward Orientation of Its Neck Linker

(2015) Merve Yusra Dogan et al.   Cell Reports

High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis

(2014) Gregory M. Alushin et al.   CELL

Structure of human cytoplasmic dynein-2 primed for its power stroke

(2014) Helgo Schmidt et al.   NATURE

Structural mechanism of the dynein power stroke

(2014) Jianfeng Lin et al.   NATURE CELL BIOLOGY

Cytoplasmic dynein transports cargos via load-sharing between the heads

(2014) Vladislav Belyy et al.   Nature Communications

Tension on the linker gates the ATP-dependent release of dynein from microtubules

(2014) Frank B. Cleary et al.   Nature Communications

Bidirectional helical motility of cytoplasmic dynein around microtubules

(2014) Sinan Can et al.   eLife

Functions and mechanics of dynein motor proteins

(2013) Anthony J. Roberts et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles

(2012) Robert B. Best et al.   Journal of Chemical Theory and Computation

The 2.8 Å crystal structure of the dynein motor domain

(2012) Takahide Kon et al.   NATURE

Insights into dynein motor domain function from a 3.3-Å crystal structure

(2012) Helgo Schmidt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dynein achieves processive motion using both stochastic and coordinated stepping

(2012) Weihong Qiu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural Basis for Microtubule Binding and Release by Dynein

(2012) W. B. Redwine et al.   SCIENCE

Cytoplasmic Dynein Moves Through Uncoordinated Stepping of the AAA+ Ring Domains

(2011) M. A. DeWitt et al.   SCIENCE

AAA+ Ring and Linker Swing Mechanism in the Dynein Motor

(2009) Anthony J. Roberts et al.   CELL

Helix sliding in the stalk coiled coil of dynein couples ATPase and microtubule binding

(2009) Takahide Kon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure and Functional Role of Dynein's Microtubule-Binding Domain

(2008) A. P. Carter et al.   SCIENCE