20-Hydroxy-3-Oxolupan-28-Oic Acid Attenuates Inflammatory Responses by Regulating PI3K–Akt and MAPKs Signaling Pathways in LPS-Stimulated RAW264.7 Macrophages

Syk and Src-targeted anti-inflammatory activity of aripiprazole, an atypical antipsychotic

(2018) Sulgi Yoo et al.   BIOCHEMICAL PHARMACOLOGY

The role of inflammatory cytokines and tumor associated macrophages (TAMs) in microenvironment of pancreatic cancer

(2018) Saeed Farajzadeh Valilou et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Interleukin-6: A promising cytokine to support liver regeneration and adaptive immunity in liver pathologies

(2018) Sidrah Naseem et al.   CYTOKINE & GROWTH FACTOR REVIEWS

ROS and RNS signalling: adaptive redox switches through oxidative/nitrosative protein modifications

(2018) N. T. Moldogazieva et al.   FREE RADICAL RESEARCH

Macrophages: Their role, activation and polarization in pulmonary diseases

(2018) Shweta Arora et al.   IMMUNOBIOLOGY

Anti-inflammatory effect of Apo-9′-fucoxanthinone via inhibition of MAPKs and NF-kB signaling pathway in LPS-stimulated RAW 264.7 macrophages and zebrafish model

(2018) Eun-A Kim et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Different levels of pro- and anti-inflammatory cytokines in patients with unipolar and bipolar depression

(2018) Ruizhi Mao et al.   JOURNAL OF AFFECTIVE DISORDERS

Anti-inflammatory lupane triterpenoids from Menyanthes trifoliata

(2018) Jiao-Jiao Zhu et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Cirsimarin, a flavone glucoside from the aerial part of Cirsium japonicum var. ussuriense (Regel) Kitam. ex Ohwi, suppresses the JAK/STAT and IRF-3 signaling pathway in LPS-stimulated RAW 264.7 macrophages

(2018) Hee-Soo Han et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Xinjiang herbal tea exerts immunomodulatory activity via TLR2/4-mediated MAPK signaling pathways in RAW264.7 cells and prevents cyclophosphamide-induced immunosuppression in mice

(2018) Yujia Bai et al.   JOURNAL OF ETHNOPHARMACOLOGY

Lanostane triterpenoids from Tricholoma pardinum with NO production inhibitory and cytotoxic activities

(2018) Shuai-Bing Zhang et al.   PHYTOCHEMISTRY

Pro-inflammatory cytokines: The link between obesity and osteoarthritis

(2018) Tiantian Wang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Innate lymphoid cells, mediators of tissue homeostasis, adaptation and disease tolerance

(2018) Nora Branzk et al.   IMMUNOLOGICAL REVIEWS

Semisynthesis and Inhibitory Effects of Solidagenone Derivatives on TLR-Mediated Inflammatory Responses

(2018) Irene Cuadrado et al.   MOLECULES

Protective effect of triterpenes against diabetes-induced β-cell damage: An overview of in vitro and in vivo studies

(2018) Sihle E. Mabhida et al.   PHARMACOLOGICAL RESEARCH

Inhibitory-κB Kinase (IKK) α and Nuclear Factor-κB (NFκB)-Inducing Kinase (NIK) as Anti-Cancer Drug Targets

(2018) Andrew Paul et al.   Cells

Early inflammatory profiling of schwannoma cells induced by lipopolysaccharide

(2017) Marcela Kohoutková et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Xanthotoxin suppresses LPS-induced expression of iNOS, COX-2, TNF-α, and IL-6 via AP-1, NF-κB, and JAK-STAT inactivation in RAW 264.7 macrophages

(2017) Seung-Bin Lee et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Roles of Nitric Oxide Synthase Isoforms in Neurogenesis

(2017) Cheong-Meng Chong et al.   MOLECULAR NEUROBIOLOGY

Inflammation, metaflammation and immunometabolic disorders

(2017) Gökhan S. Hotamisligil   NATURE

A dibenzoylmethane derivative inhibits lipopolysaccharide-induced NO production in mouse microglial cell line BV-2

(2017) Katsura Takano et al.   NEUROCHEMISTRY INTERNATIONAL

Inhibition of nitric oxide production by natural oxyprenylated coumarins and alkaloids in RAW 264.7 cells

(2017) Salvatore Genovese et al.   Phytochemistry Letters

Berberine inhibits the LPS‑induced proliferation and inflammatory response of stromal cells of adenomyosis tissues mediated by the LPS/TLR4 signaling pathway

(2017) Li Liu et al.   Experimental and Therapeutic Medicine

Chiisanoside, a triterpenoid saponin, exhibits anti-tumor activity by promoting apoptosis and inhibiting angiogenesis

(2017) Xingbo Bian et al.   RSC Advances

Poligalen, a new coumarin from Polygala boliviensis , reduces the release of TNF and IL-6 independent of NF-kB downregulation

(2016) Danielle F. Silva et al.   FITOTERAPIA

Cnidilide, an alkylphthalide isolated from the roots of Cnidium officinale , suppresses LPS-induced NO, PGE 2 , IL-1β, IL-6 and TNF-α production by AP-1 and NF-κB inactivation in RAW 264.7 macrophages

(2016) Woo-Seok Lee et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The dichloromethane fraction from Mahonia bealei (Fort.) Carr. leaves exerts an anti-inflammatory effect both in vitro and in vivo

(2016) Weicheng Hu et al.   JOURNAL OF ETHNOPHARMACOLOGY

In vivo and in vitro anti-inflammatory effects of Zao-Jiao-Ci (the spine of Gleditsia sinensis Lam.) aqueous extract and its mechanisms of action

(2016) Kai Kai Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

Roles of NF-κB in Cancer and Inflammatory Diseases and Their Therapeutic Approaches

(2016) Mi Park et al.   Cells

Inhibitory effects of compounds from Styrax obassia on NO production

(2015) Thao Quyen Cao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Melittin has a chondroprotective effect by inhibiting MMP-1 and MMP-8 expressions via blocking NF-κB and AP-1 signaling pathway in chondrocytes

(2015) Yun-Jeong Jeong et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The medicinal uses of the genus Mahonia in traditional Chinese medicine: An ethnopharmacological, phytochemical and pharmacological review

(2015) Jian-Ming He et al.   JOURNAL OF ETHNOPHARMACOLOGY

Redox stress unbalances the inflammatory cytokine network: role in autoinflammatory patients and healthy subjects

(2015) Rosa Lavieri et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Control of macrophage metabolism and activation by mTOR and Akt signaling

(2015) Anthony J. Covarrubias et al.   SEMINARS IN IMMUNOLOGY

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Inflammatory response of macrophages in infection

(2014) Ling Zhang et al.   Hepatobiliary & Pancreatic Diseases International

Proteomics analysis of Mahonia bealei leaves with induction of alkaloids via combinatorial peptide ligand libraries

(2014) Lin Zhang et al.   Journal of Proteomics

Alkaloids from Mahonia bealei posses anti-H+/K+-ATPase and anti-gastrin effects on pyloric ligation-induced gastric ulcer in rats

(2014) Su-Li Zhang et al.   PHYTOMEDICINE

Macrophage polarization and function with emphasis on the evolving roles of coordinated regulation of cellular signaling pathways

(2013) Dexi Zhou et al.   CELLULAR SIGNALLING

Suppression of iNOS and COX-2 expression by flavokawain A via blockade of NF-κB and AP-1 activation in RAW 264.7 macrophages

(2013) Dong-Joo Kwon et al.   FOOD AND CHEMICAL TOXICOLOGY

Inhibition of Lipopolysaccharide-Induced Proinflammatory Responses by Buddleja officinalis Extract in BV-2 Microglial Cells via Negative Regulation of NF-kB and ERK1/2 Signaling

(2013) Won-Jun Oh et al.   MOLECULES

Signaling pathways bridging microbial-triggered inflammation and cancer

(2012) Maulilio John Kipanyula et al.   CELLULAR SIGNALLING

Phlorofucofuroeckol A inhibits the LPS-stimulated iNOS and COX-2 expressions in macrophages via inhibition of NF-κB, Akt, and p38 MAPK

(2011) A.-Reum Kim et al.   TOXICOLOGY IN VITRO

Antioxidant and antiproliferative properties of water extract from Mahonia bealei (Fort.) Carr. leaves

(2010) Weicheng Hu et al.   FOOD AND CHEMICAL TOXICOLOGY

Diosgenin inhibits macrophage-derived inflammatory mediators through downregulation of CK2, JNK, NF-κB and AP-1 activation

(2010) Da-Hye Jung et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Miyabenol A Inhibits LPS-Induced NO Production via IKK/IκB Inactivation in RAW 264.7 Macrophages: Possible Involvement of the p38 and PI3K Pathways

(2008) Kuei-Ting Ku et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Cytotoxic lupane-, secolupane-, and oleanane-type triterpenes fromViburnum awabuki

(2008) Ali A. El-Gamal   NATURAL PRODUCT RESEARCH