Review
Chemistry, Analytical
Yahan Cui, Lan Ding, Jie Ding
Summary: Magnetic imprinted polymers (MMIPs) are synthetic polymeric materials that have wide-ranging applications in sample processing. By combining magnetic separation technology, MMIPs not only have high selectivity for adsorbing target analytes, but also provide convenience for rapid separation and processing of large sample volumes. This review summarizes recent advanced preparation strategies of MMIPs and highlights their applications in complex samples.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Jialing Zhao, Hui He, Zhanchen Guo, Zhen Liu
Summary: Phosphorylation is a common post-translational modification in mammals and is related to various diseases. Molecularly imprinted polymers (MIPs) show unique advantages as phosphorylation recognition reagents, but their performance is currently not ideal. The new approach RMTD-SIC allows for the preparation of monodispersed imprinted nanoparticles for improved phosphorylation recognition.
ANALYTICAL CHEMISTRY
(2021)
Review
Polymer Science
Simonas Ramanavicius, Arunas Jagminas, Arunas Ramanavicius
Summary: This review outlines the important directions and applications of polymer-based semiconducting materials in affinity sensors, focusing on the bioanalytical application of conducting polymers such as polypyrrole and polyaniline. It also discusses advancements in polymerization techniques and analytical signal transduction methods applied in affinity sensors. Additionally, the review highlights the development and application of molecularly imprinted polymer-based structures as potential replacements for expensive affinity reagents.
Article
Chemistry, Multidisciplinary
Tutku Beduk, Matilde Gomes, Jose Ilton De Oliveira Filho, Saptami Suresh Shetty, Walaa Khushaim, Ricardo Garcia-Ramirez, Ceren Durmus, Abdellatif Ait Lahcen, Khaled Nabil Salama
Summary: This article introduces a portable potentiostat device integrated with a laser-scribed graphene (LSG) sensor for the detection of BPA in water. The device is low-cost, practical, sensitive, and selective, providing high sensitivity and accuracy in BPA detection.
FRONTIERS IN CHEMISTRY
(2022)
Review
Chemistry, Analytical
Ying Pan, Mengfan Wu, Mingjiao Shi, Peizheng Shi, Ningbin Zhao, Yangguang Zhu, Hassan Karimi-Maleh, Chen Ye, Cheng-Te Lin, Li Fu
Summary: This review provides a comprehensive overview of recent advances in molecularly imprinted electrochemical sensors (MIES) for detecting Bisphenol A (BPA). Key findings show that MIES demonstrate comparable or superior detection limits to conventional methods, and exhibit excellent selectivity between BPA and structural analogs. Innovations in nanomaterials, novel monomers, and fabrication techniques have improved the sensitivity, selectivity, and stability of MIES. However, limitations exist in reproducibility, selectivity, and stability. Nonetheless, MIES offer a low-cost portable detection method suitable for on-site BPA monitoring in diverse sectors.
Review
Chemistry, Analytical
Mayank Garg, Nicole Pamme
Summary: This review focuses on the removal strategies of templates from molecularly imprinted polymers (MIPs) used in diagnostic biosensors. Chemical-based and electrochemical-based template extraction approaches are summarized and evaluated, providing guidance for researchers in the fields of analytical chemistry, diagnostics, and materials science for the design of MIP-based sensors.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Polymer Science
Xiaoyue Zhao, Yong Wang, Pan Zhang, Zhemiao Lu, Yin Xiao
Summary: This review summarizes recent advances in the application of cyclodextrin-based molecular imprinting polymers (MIPs) in sample preparation, detection, sensing, and drug delivery over the past five years. It also discusses the specific roles of cyclodextrins in MIPs and elaborates on the challenges and future prospects in the application of cyclodextrins in MIPs.
MACROMOLECULAR RAPID COMMUNICATIONS
(2021)
Review
Polymer Science
Semra Akgonullu, Seckin Kilic, Cem Esen, Adil Denizli
Summary: The accurate detection of biological substances such as proteins has always been a hot topic in scientific research. Biomimetic sensors seek to imitate sensitive and selective mechanisms of biological systems and integrate these traits into applicable sensing platforms. Molecular imprinting technology has been extensively practiced in many domains, producing molecular recognition materials with specific capabilities. Molecularly imprinted polymers (MIPs), also known as plastic antibodies, are artificial receptors with high-affinity binding sites for a particular molecule or compound. MIPs for protein recognition are expected to have high affinity through interactions between polymer matrices and functional groups of the target protein. This critical review discusses recent advances in the synthesis, characterization, and application of MIP-based sensor platforms for protein detection.
Review
Chemistry, Analytical
Nadja Leibl, Karsten Haupt, Carlo Gonzato, Luminita Duma
Summary: The development of MIP-based chemosensors is driven by the need for simplicity and high selectivity in detecting various compounds in fields such as medical diagnosis, environmental monitoring, and explosive detection. Research efforts have been made to further develop this field, with a focus on discussing the pros and cons of MIP-based chemosensors.
Article
Chemistry, Analytical
Eslam M. Hamed, Sam F. Y. Li
Summary: This article discusses the methods and types of sensors using molecularly imprinted polymers (MIPs) for the detection and analysis of Bisphenol A (BPA), as well as the wide-ranging applications of MIPs in environmental, food, and biological samples. Future trends and developments are also examined.
TRENDS IN ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2022)
Review
Chemistry, Analytical
Kshitij R. B. Singh, Arunadevi Natarajan
Summary: This review focuses on the formation mechanism of molecularly imprinted polymers (MIPs), the role of co-monomers and porogen, and the performance of optical sensors. The use of MIPs in microorganism detection and cancer diagnosis is also discussed, along with the challenges faced in their application.
Review
Chemistry, Physical
Simonas Ramanavicius, Arunas Ramanavicius
Summary: Achievements in polymer chemistry have enabled the design of artificial phase boundaries through the modification of selected molecules and larger structures. These structures have proven to be useful for the development of new materials suitable for affinity chromatography and sensors. This review provides an overview of the synthesis of molecularly imprinted polymers (MIPs) and their applicability in the design of affinity sensors. The use of conducting polymers, such as polypyrrole, polyaniline, and polythiophene, shows promising capabilities for molecular imprinting. The review also discusses methods for the synthesis of conducting polymer-based MIPs and the challenges and trends in MIP technology.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2022)
Review
Chemistry, Analytical
Simonas Ramanavicius, Inga Morkvenaite-Vilkonciene, Urte Samukaite-Bubniene, Vilma Ratautaite, Ieva Plikusiene, Roman Viter, Arunas Ramanavicius
Summary: This review focuses on the development of molecularly imprinted polymers (MIPs) and their application in sensor design. MIP-based conducting polymers, such as polypyrrole, are frequently used in sensor design due to their unique properties. The review also provides an overview of other materials that can be molecularly imprinted and discusses methods for designing MIP-based sensing structures and transducing analytical signals. Furthermore, it explores expected new trends and horizons in the application of MIP-based structures.
Article
Chemistry, Analytical
Goksu Ozcelikay, Ahmet Cetinkaya, Esen Bellur Atici, Sibel A. Ozkan
Summary: In this study, an electroanalytical quantification method for sugammadex was developed using molecular imprinting via the electropolymerization technique. The EP-MIP(SUG)/SPAuE sensor exhibited high sensitivity and specificity/selectivity, as demonstrated by its ability to detect sugammadex in biological fluids and differentiate it from similar molecules. The EP-MIP(SUG)/SPAuE sensor showed good analytical performance and validation parameters according to ICH guidelines, making it a promising tool for quantitative analysis of sugammadex in various samples.
ANALYTICAL METHODS
(2023)
Review
Chemistry, Analytical
Simonas Ramanavicius, Urte Samukaite-Bubniene, Vilma Ratautaite, Mikhael Bechelany, Arunas Ramanavicius
Summary: This paper outlines the development of molecularly imprinted polymer (MIP) based sensors, focusing on conducting polymers and their versatile properties for sensor applications. It discusses the design of sensing structures using various polymerization methods and outlines physicochemical methods for analytical signal transduction. The advances, trends, and perspectives in MIP application are also discussed.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2022)
