Article
Sport Sciences
Steven A. Garcia, Derek N. Pamukoff, Alexa K. Johnson, Riann M. Palmieri-Smith
Summary: Individuals with anterior cruciate ligament reconstruction (ACLR) exhibit limb underloading behaviors during walking. This study evaluates if underloading behaviors are apparent in ACLR limbs when using cumulative load metrics and how load metrics change in response to walking speed modifications.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Article
Geochemistry & Geophysics
Sheng Li, Ziming Xiong, Pengxian Fan, Haozhe Xing, Kaidi Xie
Summary: Existing experimental evidence shows that the propagation of explosive waves in soils is significantly affected by the degree of saturation. Impact tests were conducted to investigate the effect of water saturation on the stress wave attenuation ability of infilled joints. The results revealed the adverse effect of water on the wave absorption properties of the joints, indicating the need for careful consideration in the design of underground protective structures.
Article
Sport Sciences
Alexa K. Johnson, Nicholas R. Heebner, Emily R. Hunt, Caitlin E. W. Conley, Cale A. Jacobs, Mary L. Ireland, John P. Abt, Christian Lattermann
Summary: The study indicates that patient-reported outcomes at 1 and 6 months after ACLR surgery are associated with running mechanics 6 months post-surgery. The ACLR limb showed lower loading while the uninvolved limb demonstrated higher loading, suggesting a greater need for running rehabilitation after ACLR.
SPORTS HEALTH-A MULTIDISCIPLINARY APPROACH
(2023)
Article
Orthopedics
Wouter Beel, Philipp Schuster, Stefan Michalski, Philipp Mayer, Michael Schlumberger, Lotta Hielscher, Joerg Richter
Summary: This study investigated the prevalence of an increased posterior tibial slope (PTS) in a population with ACL graft insufficiencies and examined whether the prevalence and absolute PTS increased with an increasing number of graft insufficiencies. The survival time of the first ACL graft was also evaluated. The results showed that there was a 35% prevalence of increased PTS in the studied patient cohort, and patients with increased PTS had a shorter survival time of the first ACL graft.
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY
(2023)
Article
Pharmacology & Pharmacy
Yujing Wu, Bang Lou, Ning Zheng, Xuhui Zhou, Ying Gao, Weiyong Hong, Qingliang Yang, Gensheng Yang
Summary: This study presents chromatophore nanoparticles embedded with FOF1-ATPase motors to enhance mucus penetration and improve drug absorption in mucosal tissues. The results show that these motor-embedded nanoparticles successfully increase mucus permeation and exhibit promising potential for glioma therapy.
Article
Biochemistry & Molecular Biology
Diana Araujo, Matilde Martins, Filomena Freitas
Summary: The polysaccharide FucoPol has shown great potential as a biomaterial in the biomedical field due to its good mechanical properties, biocompatibility, and anti-inflammatory activity. In this study, FucoPol hydrogel membranes (HMs) were loaded with caffeine or diclofenac sodium using diffusion or mixing methods. The diffusion method led to higher caffeine loading, while the mixing method resulted in higher diclofenac sodium loading. The HM1_DCAF membranes had increased mechanical and rheological parameters compared to the HM1_DDS membranes, possibly due to leaching during the drug-loading process. The release profiles showed fast release for diffusion-loaded membranes and prolonged release for mixing-loaded membranes. These findings support the suitability of FucoPol HMs as platforms for topical drug delivery.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Multidisciplinary Sciences
Bolang Zhang, Kaisheng Chen, Xing Hu, Xingwei Zhang, Guofu Luo, Rongya Chen
Summary: In this study, the deformation characteristics of subgrade soil under intermittent cyclic loading were investigated by replacing the Newtonian dashpot in the generalized Kelvin model with the fractional Abel dashpot and establishing a fractional generalized Kelvin model. Subsequently, a nonlinear viscoplastic body model considering damage was proposed, and it was connected in series with the improved fractional generalized Kelvin model to obtain the deformation constitutive model of soil under intermittent cyclic loading. The effectiveness and applicability of the model were analyzed, and comparisons with other constitutive models were made. The results demonstrated that the established constitutive model could effectively reflect the combined effect of confining pressure, frequency, dynamic stress amplitude, and other factors on the cumulative plastic strain of soil, and accurately characterize the development law of different cumulative plastic strain curves of soil.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Multidisciplinary
Fangjian Shan, Jun Hu, Chuan Gu, Yue Zhou, Zexin Zhang, Gaojian Chen
Summary: Glyco-micromotors were successfully synthesized in situ directed by multifunctional glycopolymers, capable of loading and guiding bacteria with different individual and group motions.
CHEMICAL COMMUNICATIONS
(2022)
Article
Business, Finance
Xuan Vinh Vo, Thi Hoang Anh Pham, Thang Ngoc Doan, Hiep Ngoc Luu
Summary: The study finds that banks with more able managers produce higher amount of loans and have greater loan quality, regardless of bank size and time period. These results are robust to different econometric specifications and alternative classifications of managerial ability.
FINANCE RESEARCH LETTERS
(2021)
Article
Orthopedics
Yixuan Zhao, Chen Ze, Longfei Li, Xipeng Wu, Li Wei
Summary: This study investigated the changes in 30° and 60° position sense in patients with ACL injury at different time points after injury and reconstruction. The results showed that ACL injury had a greater impact on 30° position sense, while the impact on 60° position sense was smaller. Proprioception recovery training should be initiated early after injury for better outcomes.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Article
Orthopedics
Sameer R. Oak, William A. Cantrell, Faysal Altahawi, Xiaojuan Li, Carl S. Winalski, David C. Flanigan, Emily K. Reinke, Laura J. Huston, Morgan H. Jones, Kurt P. Spindler
Summary: In this study, knees with ACLR using a BTB autograft did not show significant early signs of posttraumatic osteoarthritis compared to the contralateral uninjured knee 2 years after ACLR. Larger studies are needed to confirm these findings and accurately assess the difference between the operative and contralateral knees.
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2021)
Article
Biophysics
Yue Shen, Quanling Guo, Tiantian Zhang, Longgang Wang, Shengfu Chen, Xifa Lan, Qiurong Li, Haiyan Xiao
Summary: By modifying the surface of amphiphilic dendrimer and incorporating drugs into micelles, zwitterionic nanodrugs with high drug loading and enhanced anti-tumor ability were successfully prepared.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Cardiac & Cardiovascular Systems
Ashley Y. Choi, Oliver K. Jawitz, Vignesh Raman, Michael S. Mulvihill, Samantha E. Halpern, Yaron D. Barac, Jacob A. Klapper, Matthew G. Hartwig
Summary: The study found that nontransplantation of donation after circulatory death lungs was associated with potentially modifiable factors such as smoking history, clinical infection, and low PaO2/FiO(2) ratio. Furthermore, interventions to increase consent and standardize donation after circulatory death donor management, including selective use of ex vivo lung perfusion, may increase use and the donor pool.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2021)
Article
Geochemistry & Geophysics
Yutao Li, Faning Dang, Mei Zhou, Jie Ren
Summary: The study found that concrete exhibits different fracturing characteristics under dynamic loading, with the fractal dimension, absorption energy, and crack surface energy of concrete specimens all increasing with impact speed and decreasing with aggregate rate. The highest energy utilization rate was observed at an aggregate content of 37%. The surface energy of the crack can be used to estimate the concrete's dynamic intensity.
Article
Geochemistry & Geophysics
Jiaguang Kan, Guichen Li, Nong Zhang, Peng Wang, Changliang Han, Shun Wang
Summary: The size and distribution of pores in rocks are closely related to their physical and mechanical properties. Studying the structure and distribution of pore size inside the rock is crucial in assessing the risk of damage to a given rock volume. Under different pressures, pore diameters, and pore throat size distribution laws, the porosity of the sandstone changes with increasing load, with some pores generating cracks under pressure, increasing the risk of damage to the rock.