Cell Cycle Arrest and Cytotoxic Effects of SAHA and RG7388 Mediated through p21WAF1/CIP1 and p27KIP1 in Cancer Cells

Combination Therapy With Histone Deacetylase Inhibitors (HDACi) for the Treatment of Cancer: Achieving the Full Therapeutic Potential of HDACi

(2018) Amila Suraweera et al.   Frontiers in Oncology

B1, a novel HDAC inhibitor, induces apoptosis through the regulation of STAT3 and NF-κB

(2017) Meng-Hsuan Cheng et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Histone Deacetylase Inhibitors as Anticancer Drugs

(2017) Tomas Eckschlager et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Clinical Significance of Androgen Receptor Splice Variant-7 mRNA Detection in Circulating Tumor Cells of Men With Metastatic Castration-Resistant Prostate Cancer Treated With First- and Second-Line Abiraterone and Enzalutamide

(2017) Emmanuel S. Antonarakis et al.   JOURNAL OF CLINICAL ONCOLOGY

Validation of histone deacetylase 3 as a therapeutic target in castration-resistant prostate cancer

(2017) Abigail B. McLeod et al.   PROSTATE

MDM2 Inhibition Sensitizes Prostate Cancer Cells to Androgen Ablation and Radiotherapy in a p53-Dependent Manner

(2016) Felix Y. Feng et al.   NEOPLASIA

Synergistic effects of combined treatment with histone deacetylase inhibitor suberoylanilide hydroxamic acid and TRAIL on human breast cancer cells

(2016) Weiqiang Zhou et al.   Scientific Reports

Discovery of RG7388, a Potent and Selective p53–MDM2 Inhibitor in Clinical Development

(2013) Qingjie Ding et al.   JOURNAL OF MEDICINAL CHEMISTRY

The role of treatment modality on the utility of predictive tissue biomarkers in clinical prostate cancer: a systematic review

(2012) Naveen Kachroo et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Epigenetics as a Therapeutic Target in Breast Cancer

(2012) Roisin Connolly et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer

(2011) P N Munster et al.   BRITISH JOURNAL OF CANCER

A novel regulation of VEGF expression by HIF-1α and STAT3 in HDM2 transfected prostate cancer cells

(2011) Appu Rathinavelu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE