In vitro effects of interleukin (IL)-1 beta inhibition on the epithelial-to-mesenchymal transition (EMT) of renal tubular and hepatic stellate cells

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

IL-1 Inhibition in Systemic Juvenile Idiopathic Arthritis

(2016) Gabriella Giancane et al.   Frontiers in Pharmacology

Systemic autoimmune disease in asbestosis rapidly responding to anti-interleukin-1beta antibody canakinumab: a case report

(2015) Laura Niccoli et al.   BMC MUSCULOSKELETAL DISORDERS

Proteolytic Processing of Interleukin-1 Family Cytokines: Variations on a Common Theme

(2015) Inna S. Afonina et al.   IMMUNITY

Canakinumab for the treatment of chronic obstructive pulmonary disease

(2015) Paola Rogliani et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice

(2013) Jean-Philippe Pradere et al.   HEPATOLOGY

The secretion of IL-1β and options for release

(2013) Patrizia Piccioli et al.   SEMINARS IN IMMUNOLOGY

The Central Role of Anti-IL-1 Blockade in the Treatment of Monogenic and Multi-Factorial Autoinflammatory Diseases

(2013) Silvia Federici et al.   Frontiers in Immunology

Cytokine mediated tissue fibrosis

(2012) Lee A. Borthwick et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice

(2012) Jan Petrasek et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice

(2010) Kouichi Miura et al.   GASTROENTEROLOGY

Contribution of hepatic stellate cells and matrix metalloproteinase 9 in acute liver failure

(2010) Chunli Yan et al.   LIVER INTERNATIONAL

Canakinumab

(2010) Eugen Dhimolea   mAbs

Interleukin-1 participates in the progression from liver injury to fibrosis

(2009) Roben G. Gieling et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Inflammatory arthritis in caspase 1 gene–deficient mice: Contribution of proteinase 3 to caspase 1–independent production of bioactive interleukin-1β

(2009) Leo A. B. Joosten et al.   ARTHRITIS AND RHEUMATISM

Mechanisms of interleukin-1β release

(2009) Claudia Eder   IMMUNOBIOLOGY

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-1RI deficiency ameliorates early experimental renal interstitial fibrosis

(2009) Lynelle K. Jones et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis

(2008) Rieke Alten et al.   ARTHRITIS RESEARCH & THERAPY