Article
Clinical Neurology
Yongmei Wu, Sailan Li, Ke Hu, Juan Yang
Summary: The study found a relationship between work stress and depressive symptoms among fishermen, with hair cortisol and cortisone potentially playing a moderating role. Fishermen with low hair cortisol or high hair cortisone levels were more likely to experience depressive symptoms.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychiatry
Li Wang, Jingyi Zhang, Gen Li, Chengqi Cao, Ruojiao Fang, Ping Liu, Shu Luo, Guangyi Zhao, Yingqian Zhang, Kunlin Zhang
Summary: The study examined the role of ADCYAP1R1 polymorphism rs2267735 in Chinese trauma-exposed individuals, suggesting that interactions with other HPA axis genes may influence PTSD development.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Endocrinology & Metabolism
M. R. Sopp, T. Michael, J. Lass-Hennemann, S. Haim-Nachum, M. J. J. Lommen
Summary: The study found a positive correlation between HCC and PTSD symptoms, particularly in individuals with higher work-related trauma severity. Higher HCC predicted more posttraumatic sleep disturbances after 12 months. Further longitudinal research is needed to examine the stability of these associations.
PSYCHONEUROENDOCRINOLOGY
(2021)
Article
Clinical Neurology
Nadja Schaffter, Katharina Ledermann, Aju P. Pazhenkottil, Jurgen Barth, Ulrich Schnyder, Hansjorg Znoj, Jean-Paul Schmid, Rebecca E. Meister-Langraf, Roland von Kanel, Mary Princip
Summary: Lower serum cortisol levels measured during acute myocardial infarction hospitalization may predict more severe posttraumatic stress disorder symptoms at three and 12 months after hospital discharge. The study's findings are limited to patients with high acute peri-traumatic distress and without acute severe depressive episodes.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Isabel Jaramillo, Marlene Karl, Luisa Bergunde, Judith T. Mack, Victoria Weise, Kerstin Weidner, Wei Gao, Susann Steudte-Schmiedgen, Susan Garthus-Niegel
Summary: This study investigated the association between negative childbirth experiences and long-term glucocorticoids, and found that a negative objective birth experience was associated with an increased HairF/HairE ratio, which may be a biomarker for identifying women at risk for developing postpartum depression (PPD). Subjective birth experience was not directly related to hair cortisol concentrations, but was a significant predictor for PPD symptoms.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychiatry
Sarah Schumacher, Sinha Engel, Hannah Klusmann, Helen Niemeyer, Annika Kuester, Sebastian Burchert, Nadine Skoluda, Heinrich Rau, Urs M. Nater, Gerd-Dieter Willmund, Christine Knaevelsrud
Summary: Dysregulated functioning of the hypothalamic-pituitary-adrenal (HPA) axis is associated with PTSD. Hair cortisol concentrations (HCC) can retrospectively evaluate HPA axis secretion and are considered a marker of HPA axis activity. The study found that trauma exposure has a differential impact on HPA axis activity, and cumulative cortisol secretion can serve as a psychobiological indicator of trauma exposure.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Agriculture, Dairy & Animal Science
Stefano Pallotti, Dario Pediconi, Alessandro Valbonesi, Carlo Renieri, Sun Haizhou, Zhou Junwen, Marco Antonini
Summary: The study aims to describe the phenotypic correlation between the characteristics of the coarse guard hair and the other fiber. It found positive correlations between guard hair length and guard hair diameter as well as the down fiber length, and negative correlations between guard hair diameter and its coefficient of variation, and between the down fiber diameter and the coefficient of variation of down fiber diameter. Body weight at first combing showed no correlation with any other traits.
Article
Clinical Neurology
Hannah Bryson, Melissa Middleton, Hamidul Huque, Fiona Mensah, Sharon Goldfeld, Anna M. H. Price
Summary: The study found that there was no clear association between mothers' self-reported mental health symptoms and hair cortisol concentrations (HCC), except for high depression symptom severity being related to higher HCC. Limitations of the study include the use of self-reported symptoms measured for the preceding week with HCC capturing average cortisol over three months.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Fan Yang, Paul Lodder, Mingqi Fu, Jing Guo
Summary: This study examines the changes in the network structure of Posttraumatic Stress Symptoms (PTSS) and depressive symptoms among adult survivors of the Wenchuan earthquake in China over a six-year period. The results show that the network connections between symptoms varied across waves, and core symptom clusters for PTSS and depressive symptoms were identified.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Endocrinology & Metabolism
Katrin V. Hummel, Julia Schellong, Sebastian Trautmann, Sylvia Kummer, Sabine Huerrig, Michael Klose, Ilona Croy, Kerstin Weidner, Clemens Kirschbaum, Susann Steudte-Schmiedgen
Summary: The study investigated the relationship between hair cortisol concentrations (HCC), childhood maltreatment (CM), and treatment outcomes, finding that changes in HCC or CM were not predictive of improvement in PTSD symptoms. However, attenuated pre-treatment HCC predicted less improvement in overall symptomatology during treatment, an effect that diminished after adjusting for baseline dissociative symptoms.
PSYCHONEUROENDOCRINOLOGY
(2021)
Article
Endocrinology & Metabolism
S. Steudte-Schmiedgen, S. Schaelicke, L. Bergunde, M. Karl, V. Weise, J. Junge-Hoffmeister, S. Schumacher, T. von Soest, K. Weidner, C. Kirschbaum, S. Garthus-Niegel
Summary: Childbirth-related posttraumatic stress disorder (CB-PTSD) is associated with maternal trauma history and long-term glucocorticoid (GC) levels, but these associations were not significant after correcting for multiple testing. Trauma history predicted higher CB-PTSD symptoms, but hair GC levels did not predict or mediate the relationship between trauma history and CB-PTSD symptoms. The subjective birth experience moderated the relationship between hair GC levels and CB-PTSD symptoms.
PSYCHONEUROENDOCRINOLOGY
(2023)
Article
Psychology, Developmental
Isabelle Ouellet-Morin, Christina Cantave, Stephane Paquin, Marie-Claude Geoffroy, Mara Brendgen, Frank Vitaro, Richard Tremblay, Michel Boivin, Sonia Lupien, Sylvana Cote
Summary: This study found a nonlinear association between peer victimization and HCC for boys, with changes in peer victimization related to HCC for both boys and girls. Peer victimization predicted more depressive symptoms for all participants, except for those with lower HCC. These findings suggest persistent dysregulation of the HPA axis following exposure to chronic adversity, which may vary by sex and severity of victimization.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2021)
Article
Pediatrics
Mia A. Mclean, Olivia C. Scoten, Wayne Yu, Xiang Y. Ye, Julie Petrie, Paige T. Church, Amuchou S. Soraisham, Lucia S. Mirea, Joanne Weinberg, Anne R. Synnes, Karel O'Brien, Ruth E. Grunau
Summary: The study evaluates whether implementing Family Integrated Care (FICare) in the neonatal intensive care unit has a positive impact on the physiological and psychological well-being of premature infants and their mothers. The results indicate that FICare lowers maternal physiological stress and improves child behavior.
JOURNAL OF PEDIATRICS
(2022)
Article
Biochemistry & Molecular Biology
Linlin Xu, Xiaofeng Wei, Guanxia Liang, Dina Zhu, Yanxia Zhang, Yang Zhang, Xuan Shang
Summary: A novel mutation in the ANK1 gene was found to be associated with hereditary spherocytosis (HS), and the phenotypic difference between father and son may be attributed to the lower expression of the mutant allele. This study has important implications for improving the clinical diagnosis and genetic counseling of HS.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
(2023)
Article
Clinical Neurology
Anna Szep, Nadine Skoluda, Susan Schloss, Katja Becker, Ursula Pauli-Pott, Urs M. Nater
Summary: This study examined the impact of child and maternal ADHD symptoms on mothers' perceived chronic stress and hair cortisol concentration. The findings suggest that maternal ADHD and depressive symptoms play a significant role in maternal perceived chronic stress.
JOURNAL OF NEURAL TRANSMISSION
(2021)
Review
Neurosciences
Maya Jammoul, Dareen Jammoul, Kevin K. Wang, Firas Kobeissy, Ralph G. Depalma
Summary: This article reviews the possible mechanisms by which traumatic brain injury (TBI) may stimulate the development of opioid use disorder (OUD) and discusses the interaction between these two processes. CNS damage due to TBI appears to drive adverse effects of subsequent OUD, with pain being a risk factor for opioid use after TBI.
BIOLOGICAL PSYCHIATRY
(2024)
Article
Neurosciences
Danusa Mar Arcego, Jan-Paul Buschdorf, Nicholas O'Toole, Zihan Wang, Barbara Barth, Irina Pokhvisneva, Nirmala Arul Rayan, Sachin Patel, Euclides Jose de Mendonca Filho, Patrick Lee, Jennifer Tan, Ming Xuan Koh, Chu Ming Sim, Carine Parent, Randriely Merscher Sobreira de Lima, Andrew Clappison, Kieran J. O'Donnell, Carla Dalmaz, Janine Arloth, Nadine Provencal, Elisabeth B. Binder, Josie Diorio, Patricia Pelufo Silveira, Michael J. Meaney
Summary: This study investigates the impact of environmental influences on mental health by integrating transcriptomic data from animal models with human data. The results suggest that hippocampal glucocorticoid-related transcriptional activity mediates the effects of early adversity on neural mechanisms implicated in psychiatric disorders.
BIOLOGICAL PSYCHIATRY
(2024)
Article
Neurosciences
Milenna T. van Dijk, Ardesheer Talati, Pratik Kashyap, Karan Desai, Nora C. Kelsall, Marc J. Gameroff, Natalie Aw, Eyal Abraham, Breda Cullen, Jiook Cha, Christoph Anacker, Myrna M. Weissman, Jonathan Posner
Summary: This study found that maternal stress is associated with future depressive symptoms and alterations in microstructure of the dentate gyrus (DG) in offspring. These results were consistent across two independent cohorts.
BIOLOGICAL PSYCHIATRY
(2024)
Article
Neurosciences
Josephine C. McGowan, Liliana R. Ladner, Claire X. Shubeck, Juliana Tapia, Christina T. LaGamma, Amanda Anqueira-Gonzalez, Ariana DeFrancesco, Briana K. Chen, Holly C. Hunsberger, Ezra J. Sydnor, Ryan W. Logan, Tzong-Shiue Yu, Steven G. Kernie, Christine A. Denny
Summary: Traumatic brain injury (TBI) leads to fear generalization by altering fear memory traces, and this symptom can be improved with (R,S)-ketamine.
BIOLOGICAL PSYCHIATRY
(2024)