Co-inhibition of PGF and VEGF blocks their expression in mononuclear phagocytes and limits neovascularization and leakage in the murine retina

Ranibizumab and Bevacizumab but Not Aflibercept Inhibit Proliferation of Primary Human Retinal Pigment Epithelium in vitro

(2018) Lorenzo Parisi et al.   OPHTHALMOLOGICA

Anti-vascular endothelial growth factor for neovascular age-related macular degeneration: a meta-analysis of randomized controlled trials

(2018) Chu Luan Nguyen et al.   BMC Ophthalmology

Intravitreal aflibercept protects photoreceptors of mice against excessive light exposure

(2018) Yoshiki Kuse et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

The role of placental growth factor (PlGF) and its receptor system in retinal vascular diseases

(2018) Tine Van Bergen et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Neutralization of placental growth factor as a novel treatment option in diabetic retinopathy

(2017) Tine Van Bergen et al.   EXPERIMENTAL EYE RESEARCH

Comprehensive analysis of mouse retinal mononuclear phagocytes

(2017) Anika Lückoff et al.   Nature Protocols

On phagocytes and macular degeneration

(2017) Xavier Guillonneau et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Aflibercept exhibits VEGF binding stoichiometry distinct from bevacizumab and does not support formation of immune-like complexes

(2016) Douglas A. MacDonald et al.   ANGIOGENESIS

Requirement for Microglia for the Maintenance of Synaptic Function and Integrity in the Mature Retina

(2016) Xu Wang et al.   JOURNAL OF NEUROSCIENCE

Oncolytic adenovirus expressing interleukin-18 improves antitumor activity of dacarbazine for malignant melanoma

(2016) Chunhua Yang et al.   Drug Design Development and Therapy

Microglia inflammatory responses are controlled by an intrinsic circadian clock

(2015) Laura K. Fonken et al.   BRAIN BEHAVIOR AND IMMUNITY

Inhibition of Ocular Neovascularization by Co-Inhibition of VEGF-A and PLGF

(2015) Xiaochuan Huo et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Parainflammation, chronic inflammation, and age-related macular degeneration

(2015) M. Chen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration

(2015) Olivier Levy et al.   JOURNAL OF NEUROSCIENCE

Retinal microglia: Just bystander or target for therapy?

(2015) Marcus Karlstetter et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Simultaneous high-resolution detection of multiple transcripts combined with localization of proteins in whole-mount embryos

(2014) Theresa Gross-Thebing et al.   BMC BIOLOGY

Capacity of aflibercept to counteract VEGF-stimulated abnormal behavior of retinal microvascular endothelial cells

(2014) Heidrun L. Deissler et al.   EXPERIMENTAL EYE RESEARCH

Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis

(2014) Wan Ling Wong et al.   Lancet Global Health

Aqueous humour levels of placental growth factor in diabetic retinopathy

(2013) Ryo Ando et al.   ACTA OPHTHALMOLOGICA

Inhibition of placental growth factor improves surgical outcome of glaucoma surgery

(2013) Tine Van Bergen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Binding affinities of vascular endothelial growth factor (VEGF) for heparin-derived oligosaccharides

(2011) Wenjing Zhao et al.   BIOSCIENCE REPORTS

Regulation of VEGF expression in human retinal cells by cytokines: Implications for the role of inflammation in age-related macular degeneration

(2011) Chandrasekharam N. Nagineni et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Further Pharmacological and Genetic Evidence for the Efficacy of PlGF Inhibition in Cancer and Eye Disease

(2010) Sara Van de Veire et al.   CELL

PlGF-1 and VEGFR-1 Pathway Regulation of the External Epithelial Hemato-Ocular Barrier

(2008) N. Miyamoto et al.   OPHTHALMIC RESEARCH