4.1 Article

Parvimonas micra: A rare cause of native joint septic arthritis

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ANAEROBE
卷 39, 期 -, 页码 26-27

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ELSEVIER SCI LTD
DOI: 10.1016/j.anaerobe.2016.02.004

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Osteomyelitis; Septic joint; Knee; Native; Parvimonas; Micromonas; Peptostreptococcus

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Parvimonas micra is a fastidious, anaerobic, gram positive coccus, which is found in normal human oral and gastrointestinal flora. It has also been known as Peptostreptococcus micros and Micromonas micros with its most recent re-classification in 2006. It has been described in association with hematogenous seeding of prosthetic joints [1,2]. Several cases of discitis and osteomyelitis have been described in association with dental procedures and periodontal disease often with a subacute presentation. However, cases of native joint septic arthritis are limited [3-5]. Per our literature review, there is one case of native knee septic arthritis described in 1999, with a prolonged time to diagnosis and treatment due to difficulty culturing P. micra. The previously reported patient experienced significant joint destruction and morbidity [6]. Advances in culture techniques and new methods of organism identification including MALDI-TOF and 16s rRNA sequencing have lead to increased identification of this organism, which may be a more frequent bone and joint pathogen than previously realized. Published by Elsevier Ltd.

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