FAM3C‐YY1 axis is essential for TGFβ‐promoted proliferation and migration of human breast cancer MDA‐MB‐231 cells via the activation of HSF1

FAM3 gene family: A promising therapeutical target for NAFLD and type 2 diabetes

(2018) Xiaoyan Zhang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Targeting the PI3K pathway in cancer: are we making headway?

(2018) Filip Janku et al.   Nature Reviews Clinical Oncology

Genetic polymorphism and expression of HSF1 gene is significantly associated with breast cancer in Saudi females

(2018) Sahar Almotwaa et al.   PLoS One

Covalent dimerization of interleukin-like epithelial-to-mesenchymal transition (EMT) inducer (ILEI) facilitates EMT, invasion, and late aspects of metastasis

(2017) Maria Kral et al.   FEBS Journal

The interleukin-like epithelial-mesenchymal transition inducer ILEI exhibits a non-interleukin-like fold and is active as a domain-swapped dimer

(2017) Anna M. Jansson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTORC2/AKT/HSF1/HuR constitute a feed-forward loop regulating Rictor expression and tumor growth in glioblastoma

(2017) B Holmes et al.   ONCOGENE

Rethinking HSF1 in Stress, Development, and Organismal Health

(2017) Jian Li et al.   TRENDS IN CELL BIOLOGY

Extracellular matrix stiffness and cell contractility control RNA localization to promote cell migration

(2017) Tianhong Wang et al.   Nature Communications

FAF1 phosphorylation by AKT accumulates TGF-β type II receptor and drives breast cancer metastasis

(2017) Feng Xie et al.   Nature Communications

Combined inhibition of AKT and HSF1 suppresses breast cancer stem cells and tumor growth

(2017) Richard L. Carpenter et al.   Oncotarget

FAM3C activates HSF1 to suppress hepatic gluconeogenesis and attenuate hyperglycemia of type 1 diabetic mice

(2017) Zhenzhen Chen et al.   Oncotarget

Preconditioning with far-infrared irradiation enhances proliferation, cell survival, and migration of rat bone marrow-derived stem cells via CXCR4-ERK pathways

(2017) Yun-Mi Jeong et al.   Scientific Reports

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The ubiquitin ligase UBE4A inhibits prostate cancer progression by targeting interleukin-like EMT inducer (ILEI)

(2016) Yanan Sun et al.   IUBMB LIFE

The Heat Shock Transcription Factor HSF1 Induces Ovarian Cancer Epithelial-Mesenchymal Transition in a 3D Spheroid Growth Model

(2016) Chase D. Powell et al.   PLoS One

The Role of YY1 in Oncogenesis and Its Potential as a Drug Target in Cancer Therapies

(2015) Jinming Shi et al.   CURRENT CANCER DRUG TARGETS

Prognostic significance of YY1 protein expression and mRNA levels by bioinformatics analysis in human cancers: A therapeutic target

(2015) Benjamin Bonavida et al.   PHARMACOLOGY & THERAPEUTICS

IL-13 Induces YY1 through the AKT Pathway in Lung Fibroblasts

(2015) Jia Guo et al.   PLoS One

ILEI: a novel marker for epithelial-mesenchymal transition and poor prognosis in colorectal cancer

(2014) Zhao-Hua Gao et al.   HISTOPATHOLOGY

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

FAM3A promotes vascular smooth muscle cell proliferation and migration and exacerbates neointima formation in rat artery after balloon injury

(2014) Shi Jia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Clathrin light chains are required for the gyrating-clathrin recycling pathway and thereby promote cell migration

(2014) Sophia R. Majeed et al.   Nature Communications

ILEI drives epithelial to mesenchymal transition and metastatic progression in the lung cancer cell line A549

(2013) Qi Song et al.   TUMOR BIOLOGY

Elevated levels of HSF1 indicate a poor prognosis in breast cancer

(2012) Stuart K Calderwood   Future Oncology

Heat Shock Factor Hsf1 Cooperates with ErbB2 (Her2/Neu) Protein to Promote Mammary Tumorigenesis and Metastasis

(2012) Caixia Xi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Restoring HSP70 deficiencies improves glucose tolerance in diabetic monkeys

(2011) Kylie Kavanagh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Biology of Transforming Growth Factor-β Signaling

(2011) Hiroaki Ikushima et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Yin Yang 1 positively regulates BRCA1 and inhibits mammary cancer formation

(2011) M-H Lee et al.   ONCOGENE

TGF-β-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI

(2010) Arindam Chaudhury et al.   NATURE CELL BIOLOGY

TGF-  Biology in Mammary Development and Breast Cancer

(2010) H. Moses et al.   Cold Spring Harbor Perspectives in Biology

Tissue-specific regulation and expression of heat shock proteins in type 2 diabetic monkeys

(2008) K. Kavanagh et al.   CELL STRESS & CHAPERONES

AKT Alters Genome-Wide Estrogen Receptor   Binding and Impacts Estrogen Signaling in Breast Cancer

(2008) P. Bhat-Nakshatri et al.   MOLECULAR AND CELLULAR BIOLOGY

Transforming Growth Factor   Engages TACE and ErbB3 To Activate Phosphatidylinositol-3 Kinase/Akt in ErbB2-Overexpressing Breast Cancer and Desensitizes Cells to Trastuzumab

(2008) S. E. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progression

(2008) C Lahsnig et al.   ONCOGENE