标题
Therapeutic Targeting of Collective Invasion in Ovarian Cancer
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 20, Issue 6, Pages 1466
出版商
MDPI AG
发表日期
2019-03-25
DOI
10.3390/ijms20061466
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Efficacy and Safety of Avelumab for Patients With Recurrent or Refractory Ovarian Cancer
- (2019) Mary L. Disis et al. JAMA Oncology
- Epithelial Mesenchymal Transition in Tumor Metastasis
- (2018) Vivek Mittal Annual Review of Pathology-Mechanisms of Disease
- PARP inhibitors in platinum-sensitive high-grade serous ovarian cancer
- (2018) Robert D. Morgan et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Phase II study of pembrolizumab (pembro) combined with pegylated liposomal doxorubicin (PLD) for recurrent platinum-resistant ovarian, fallopian tube or peritoneal cancer
- (2018) U.A. Matulonis et al. GYNECOLOGIC ONCOLOGY
- The complex ecosystem in non small cell lung cancer invasion
- (2018) Seth Haney et al. PLoS Computational Biology
- Sorafenib plus topotecan versus placebo plus topotecan for platinum-resistant ovarian cancer (TRIAS): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial
- (2018) Radoslav Chekerov et al. LANCET ONCOLOGY
- Phase II randomised discontinuation trial of cabozantinib in patients with advanced solid tumours
- (2017) Patrick Schöffski et al. EUROPEAN JOURNAL OF CANCER
- A phase 2 randomised discontinuation trial of cabozantinib in patients with ovarian carcinoma
- (2017) Ignace B. Vergote et al. EUROPEAN JOURNAL OF CANCER
- The protein serine/threonine phosphatases PP2A, PP1 and calcineurin: A triple threat in the regulation of the neuronal cytoskeleton
- (2017) Alexander Hoffman et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion
- (2017) Anna Labernadie et al. NATURE CELL BIOLOGY
- Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis
- (2017) Claire Vennin et al. Science Translational Medicine
- Isolation and functional interrogation of adult human prostate epithelial stem cells at single cell resolution
- (2017) Wen-Yang Hu et al. Stem Cell Research
- Making Heads or Tails of It: Cell–Cell Adhesion in Cellular and Supracellular Polarity in Collective Migration
- (2017) Jan-Hendrik Venhuizen et al. Cold Spring Harbor Perspectives in Biology
- SOX2 Is a Marker for Stem-like Tumor Cells in Bladder Cancer
- (2017) Fengyu Zhu et al. Stem Cell Reports
- Potential of Integrin Inhibitors for Treating Ovarian Cancer: A Literature Review
- (2017) et al. Cancers
- OCEANS: A randomized, double-blinded, placebo-controlled phase III trial of chemotherapy with or without bevacizumab (BEV) in patients with platinum-sensitive recurrent epithelial ovarian (EOC), primary peritoneal (PPC), or fallopian tube cancer (FTC).
- (2017) C. Aghajanian et al. JOURNAL OF CLINICAL ONCOLOGY
- Anti-angiogenic agents in ovarian cancer: past, present, and future
- (2016) B. J. Monk et al. ANNALS OF ONCOLOGY
- Novel Insights into the Roles of Rho Kinase in Cancer
- (2016) Lei Wei et al. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
- Characterisation of Prognosis and Invasion of Cutaneous Squamous Cell Carcinoma by Podoplanin and E-Cadherin Expression
- (2016) Kristina Hesse et al. DERMATOLOGY
- The front and rear of collective cell migration
- (2016) Roberto Mayor et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Niraparib Maintenance Therapy in Platinum-Sensitive, Recurrent Ovarian Cancer
- (2016) Mansoor R. Mirza et al. NEW ENGLAND JOURNAL OF MEDICINE
- Collective invasion of cancer: Perspectives from pathology and development
- (2016) Xiaoze Wang et al. PATHOLOGY INTERNATIONAL
- Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters
- (2016) Kevin J. Cheung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- KRT14 marks a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis
- (2016) George Papafotiou et al. Nature Communications
- Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis
- (2016) Sandra Kümper et al. eLife
- Cellular and molecular processes in ovarian cancer metastasis. A Review in the Theme: Cell and Molecular Processes in Cancer Metastasis
- (2015) Tsz-Lun Yeung et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Loss of RhoA expression prevents proliferation and metastasis of SPCA1 lung cancer cells in vitro
- (2015) Xueying Yang et al. BIOMEDICINE & PHARMACOTHERAPY
- A Novel Pharmacologic Activity of Ketorolac for Therapeutic Benefit in Ovarian Cancer Patients
- (2015) Y. Guo et al. CLINICAL CANCER RESEARCH
- Podoplanin-expressing cancer-associated fibroblasts lead and enhance the local invasion of cancer cells in lung adenocarcinoma
- (2015) Shinya Neri et al. INTERNATIONAL JOURNAL OF CANCER
- R-Ketorolac Targets Cdc42 and Rac1 and Alters Ovarian Cancer Cell Behaviors Critical for Invasion and Metastasis
- (2015) Y. Guo et al. MOLECULAR CANCER THERAPEUTICS
- Knockdown of RhoA expression alters ovarian cancer biological behavior in vitro and in nude mice
- (2015) XIAOXIA WANG et al. ONCOLOGY REPORTS
- Leader cells regulate collective cell migration via Rac activation in the downstream signaling of integrin β1 and PI3K
- (2015) Naoya Yamaguchi et al. Scientific Reports
- Cell Elasticity Is Regulated by the Tropomyosin Isoform Composition of the Actin Cytoskeleton
- (2015) Iman Jalilian et al. PLoS One
- Targeting invadopodia to block breast cancer metastasis
- (2015) Mark A Eckert et al. Oncotarget
- Tumor-Selective Response to Antibody-Mediated Targeting of αvβ3 Integrin in Ovarian Cancer
- (2015) Charles N. Landen et al. NEOPLASIA
- Exploiting the cytoskeletal filaments of neoplastic cells to potentiate a novel therapeutic approach
- (2014) Matthew Trendowski BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion
- (2014) Hilary A. Kenny et al. JOURNAL OF CLINICAL INVESTIGATION
- Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance
- (2014) Antonina V. Kurtova et al. NATURE
- Interplay of RhoA and mechanical forces in collective cell migration driven by leader cells
- (2014) M. Reffay et al. NATURE CELL BIOLOGY
- Ovarian Cancer Spheroid Cells with Stem Cell-Like Properties Contribute to Tumor Generation, Metastasis and Chemotherapy Resistance through Hypoxia-Resistant Metabolism
- (2014) Jianqun Liao et al. PLoS One
- Promotion of Colorectal Cancer Invasion and Metastasis through Activation of NOTCH–DAB1–ABL–RHOGEF Protein TRIO
- (2014) Masahiro Sonoshita et al. Cancer Discovery
- Invadopodia Are Required for Cancer Cell Extravasation and Are a Therapeutic Target for Metastasis
- (2014) Hon S. Leong et al. Cell Reports
- Paclitaxel/carboplatin with or without sorafenib in the first-line treatment of patients with stage III/IV epithelial ovarian cancer: a randomized phase II study of the Sarah Cannon Research Institute
- (2014) John D. Hainsworth et al. Cancer Medicine
- A Novel Class of Anticancer Compounds Targets the Actin Cytoskeleton in Tumor Cells
- (2013) J. R. Stehn et al. CANCER RESEARCH
- Collective Invasion in Breast Cancer Requires a Conserved Basal Epithelial Program
- (2013) Kevin J. Cheung et al. CELL
- The Involvement of RhoA and Wnt-5a in the Tumorigenesis and Progression of Ovarian Epithelial Carcinoma
- (2013) Shuo Chen et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Identification of novel ROCK inhibitors with anti-migratory and anti-invasive activities
- (2013) R A Patel et al. ONCOGENE
- Getting to Know Ovarian Cancer Ascites: Opportunities for Targeted Therapy-Based Translational Research
- (2013) Nuzhat Ahmed et al. Frontiers in Oncology
- Cell–cell and cell–matrix dynamics in intraperitoneal cancer metastasis
- (2012) Katharine L. Sodek et al. CANCER AND METASTASIS REVIEWS
- Inhibition of the Rho/ROCK pathway enhances the efficacy of cisplatin through the blockage of hypoxia-inducible factor-1α in human ovarian cancer cells
- (2012) Tsuyoshi Ohta et al. CANCER BIOLOGY & THERAPY
- AT13148 Is a Novel, Oral Multi-AGC Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity
- (2012) T. A. Yap et al. CLINICAL CANCER RESEARCH
- Phase II evaluation of dasatinib in the treatment of recurrent or persistent epithelial ovarian or primary peritoneal carcinoma: A Gynecologic Oncology Group study
- (2012) Russell J. Schilder et al. GYNECOLOGIC ONCOLOGY
- Mammary collective cell migration involves transient loss of epithelial features and individual cell migration within the epithelium
- (2012) A. J. Ewald et al. JOURNAL OF CELL SCIENCE
- Classifying collective cancer cell invasion
- (2012) Peter Friedl et al. NATURE CELL BIOLOGY
- The Rho/ROCK pathway for lysophosphatidic acid-induced proteolytic enzyme expression and ovarian cancer cell invasion
- (2012) K J Jeong et al. ONCOGENE
- Three differentiation states risk-stratify bladder cancer into distinct subtypes
- (2012) J.-P. Volkmer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Overcoming Challenges of Ovarian Cancer Stem Cells: Novel Therapeutic Approaches
- (2012) Cristóbal Aguilar-Gallardo et al. Stem Cell Reviews and Reports
- The Rho-kinase inhibitor inhibits proliferation and metastasis of small cell lung cancer
- (2011) Xueying Yang et al. BIOMEDICINE & PHARMACOTHERAPY
- A randomised, phase II study of intetumumab, an anti-αv-integrin mAb, alone and with dacarbazine in stage IV melanoma
- (2011) S O'Day et al. BRITISH JOURNAL OF CANCER
- An EGFR-Src-Arg-Cortactin Pathway Mediates Functional Maturation of Invadopodia and Breast Cancer Cell Invasion
- (2011) C. C. Mader et al. CANCER RESEARCH
- RhoA/ROCK signaling mediates plasticity of scirrhous gastric carcinoma motility
- (2011) Tasuku Matsuoka et al. CLINICAL & EXPERIMENTAL METASTASIS
- A phase II, single-arm study of the anti-α5β1 integrin antibody volociximab as monotherapy in patients with platinum-resistant advanced epithelial ovarian or primary peritoneal cancer
- (2011) Katherine M. Bell-McGuinn et al. GYNECOLOGIC ONCOLOGY
- Sorafenib in combination with weekly topotecan in recurrent ovarian cancer, a phase I/II study of the Hoosier Oncology Group
- (2011) R. Ramasubbaiah et al. GYNECOLOGIC ONCOLOGY
- Fractalkine Receptor CX3CR1 Is Expressed in Epithelial Ovarian Carcinoma Cells and Required for Motility and Adhesion to Peritoneal Mesothelial Cells
- (2011) M. Kim et al. MOLECULAR CANCER RESEARCH
- Ovarian Cancer Spheroids Use Myosin-Generated Force to Clear the Mesothelium
- (2011) Marcin P. Iwanicki et al. Cancer Discovery
- Ovarian Cancer Development and Metastasis
- (2010) Ernst Lengyel AMERICAN JOURNAL OF PATHOLOGY
- Lovastatin induces apoptosis of ovarian cancer cells and synergizes with doxorubicin: potential therapeutic relevance
- (2010) Anna Martirosyan et al. BMC CANCER
- Effect of fasudil on growth, adhesion, invasion, and migration of 95D lung carcinoma cells in vitro
- (2010) Xueying Yang et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- A randomized phase 2 study of etaracizumab, a monoclonal antibody against integrin αvβ3, ± dacarbazine in patients with stage IV metastatic melanoma
- (2010) Peter Hersey et al. CANCER
- Rho-kinase inhibitor, fasudil, suppresses glioblastoma cell line progression in vitro and in vivo
- (2010) Lin Deng et al. CANCER BIOLOGY & THERAPY
- Advances in Targeting Src in the Treatment of Breast Cancer and Other Solid Malignancies
- (2010) E. L. Mayer et al. CLINICAL CANCER RESEARCH
- Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting
- (2010) Chrisostomi Gialeli et al. FEBS Journal
- Determinants of leader cells in collective cell migration
- (2010) Antoine A. Khalil et al. Integrative Biology
- Fasudil Inhibits Lysophosphatidic Acid-Induced Invasiveness of Human Ovarian Cancer Cells
- (2010) Seiji Ogata et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Activity of Sorafenib in Recurrent Ovarian Cancer and Primary Peritoneal Carcinomatosis: A Gynecologic Oncology Group Trial
- (2010) Daniela Matei et al. JOURNAL OF CLINICAL ONCOLOGY
- Basement Membranes: Cell Scaffoldings and Signaling Platforms
- (2010) P. D. Yurchenco Cold Spring Harbor Perspectives in Biology
- Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis
- (2009) Laetitia Devy et al. CANCER RESEARCH
- Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia
- (2009) R. Poincloux et al. JOURNAL OF CELL SCIENCE
- Collective cell migration in morphogenesis, regeneration and cancer
- (2009) Peter Friedl et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Loss of E-Cadherin Promotes Ovarian Cancer Metastasis via 5-Integrin, which Is a Therapeutic Target
- (2008) K. Sawada et al. CANCER RESEARCH
- Overexpression of RhoA enhances peritoneal dissemination: RhoA suppression with Lovastatin may be useful for ovarian cancer
- (2008) Akiko Horiuchi et al. CANCER SCIENCE
- Volociximab, a Chimeric Monoclonal Antibody that Specifically Binds 5 1 Integrin: A Phase I, Pharmacokinetic, and Biological Correlative Study
- (2008) A. D. Ricart et al. CLINICAL CANCER RESEARCH
- Morphogenetic Cell Movements: Diversity from Modular Mechanical Properties
- (2008) D. J. Montell SCIENCE
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