Antioxidant Properties of Fucoidan Alleviate Acceleration and Exacerbation of Hippocampal Neuronal Death Following Transient Global Cerebral Ischemia in High-Fat Diet-Induced Obese Gerbils

Herbal Medicine in Ischemic Stroke: Challenges and Prospective

(2018) Bhakta Prasad Gaire   Chinese Journal of Integrative Medicine

Low molecular weight fucoidan ameliorates hindlimb ischemic injury in type 2 diabetic rats

(2018) Zhiqiang Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Low molecular-weight fucoidan protects against hindlimb ischemic injury in type 2 diabetic mice through enhancing endothelial nitric oxide synthase phosphorylation

(2018) Tiantian Liu et al.   Journal of Diabetes

The protective effect of melatonin on brain ischemia and reperfusion in rats and humans: In vivo assessment and a randomized controlled trial

(2018) Zhewei Zhao et al.   JOURNAL OF PINEAL RESEARCH

Chronic high-fat diet-induced obesity in gerbils increases pro-inflammatory cytokines and mTOR activation, and elicits neuronal death in the striatum following brief transient ischemia

(2018) Minah Song et al.   NEUROCHEMISTRY INTERNATIONAL

Pretreated fucoidan confers neuroprotection against transient global cerebral ischemic injury in the gerbil hippocampal CA1 area via reducing of glial cell activation and oxidative stress

(2018) Hyunjung Kim et al.   BIOMEDICINE & PHARMACOTHERAPY

In vitro and in vivo evaluation of anti-arthritic, antioxidant efficacy of fucoidan from Undaria pinnatifida (Harvey) Suringar

(2017) Abdul-Rehman Phull et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Oxidative stress-induced cognitive impairment in obesity can be reversed by vitamin D administration in rats

(2017) Ghazaleh Hajiluian et al.   NUTRITIONAL NEUROSCIENCE

Obesity-induced diet leads to weight gain, systemic metabolic alterations, adipose tissue inflammation, hepatic steatosis, and oxidative stress in gerbils (Meriones unguiculatus)

(2017) Luciana L.A. Ventura et al.   PeerJ

Association of body mass index with mortality and functional outcome after acute ischemic stroke

(2017) Weiping Sun et al.   Scientific Reports

Neuroprotection of ischemic preconditioning is mediated by thioredoxin 2 in the hippocampal CA1 region following a subsequent transient cerebral ischemia

(2016) Jae-Chul Lee et al.   BRAIN PATHOLOGY

Brain atlas of the Mongolian gerbil (Meriones unguiculatus) in CT/MRI-aided stereotaxic coordinates

(2016) Susanne Radtke-Schuller et al.   Brain Structure & Function

Antithrombotic activity of oral administered low molecular weight fucoidan from Laminaria Japonica

(2016) Xue Zhao et al.   THROMBOSIS RESEARCH

New GABAergic Neurogenesis in the Hippocampal CA1 Region of a Gerbil Model of Long-Term Survival after Transient Cerebral Ischemic Injury

(2015) Jae-Chul Lee et al.   BRAIN PATHOLOGY

Prolonged diet-induced obesity in mice modifies the inflammatory response and leads to worse outcome after stroke

(2015) Samaneh Maysami et al.   Journal of Neuroinflammation

Obesity Increases Risk of Ischemic Stroke in Young Adults

(2015) Andrew B. Mitchell et al.   STROKE

Critical role of matrix metalloprotease-9 in chronic high fat diet-induced cerebral vascular remodelling and increase of ischaemic brain injury in mice

(2014) J. Deng et al.   CARDIOVASCULAR RESEARCH

Resveratrol Protects Neurons and the Myocardium by Reducing Oxidative Stress and Ameliorating Mitochondria Damage in a Cerebral Ischemia Rat Model

(2014) Ran Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Effects of High-Fat Diet on Neuronal Damage, Gliosis, Inflammatory Process and Oxidative Stress in the Hippocampus Induced by Transient Cerebral Ischemia

(2014) Bing Chun Yan et al.   NEUROCHEMICAL RESEARCH

Importance of Preclinical Research in the Development of Neuroprotective Strategies for Ischemic Stroke

(2014) Ain A. Neuhaus et al.   JAMA Neurology

Early effects of high-fat diet on neurovascular function and focal ischemic brain injury

(2013) Weiguo Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Association of Body Mass Index and Mortality After Acute Ischemic Stroke

(2013) L. E. Skolarus et al.  

Global Cerebral Ischemia: Synaptic and Cognitive Dysfunction

(2013) Jake T. Neumann et al.   CURRENT DRUG TARGETS

Characteristics of Circle of Willis Variations in the Mongolian Gerbil and a Newly Established Ischemia-Prone Gerbil Group

(2013) X. Y. Du et al.   ILAR JOURNAL

Neuroprotective Effect of Fucoidan on H2O2-Induced Apoptosis in PC12 Cells Via Activation of PI3K/Akt Pathway

(2012) Yonglin Gao et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

The Influence of Stroke Risk Factors and Comorbidities on Assessment of Stroke Therapies in Humans and Animals

(2012) Sandeep Ankolekar et al.   International Journal of Stroke

Neuroprotective effect of fucoidin on lipopolysaccharide accelerated cerebral ischemic injury through inhibition of cytokine expression and neutrophil infiltration

(2012) Gu Hyun Kang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Neuronal damage in hippocampal subregions induced by various durations of transient cerebral ischemia in gerbils using Fluoro-Jade B histofluorescence

(2011) Dong-Kun Yu et al.   BRAIN RESEARCH

Pre- and post-treatments with escitalopram protect against experimental ischemic neuronal damage via regulation of BDNF expression and oxidative stress

(2011) Choong Hyun Lee et al.   EXPERIMENTAL NEUROLOGY

Anti-inflammatory effects of fucoidan through inhibition of NF-κB, MAPK and Akt activation in lipopolysaccharide-induced BV2 microglia cells

(2011) Hye Young Park et al.   FOOD AND CHEMICAL TOXICOLOGY

Increased Blood–Brain Barrier Permeability and Brain Edema After Focal Cerebral Ischemia Induced by Hyperlipidemia

(2011) Ayman ElAli et al.   STROKE

Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection

(2010) Hai Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

High fat diet increases hippocampal oxidative stress and cognitive impairment in aged mice: implications for decreased Nrf2 signaling

(2010) Christopher D. Morrison et al.   JOURNAL OF NEUROCHEMISTRY

Manganese Superoxide Dismutase Deficiency Exacerbates Ischemic Brain Damage Under Hyperglycemic Conditions by Altering Autophagy

(2010) Suresh L. Mehta et al.   Translational Stroke Research

Mitochondrial and apoptotic neuronal death signaling pathways in cerebral ischemia

(2009) Kuniyasu Niizuma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE