Article
Biochemistry & Molecular Biology
L. Viridiana Soto-Robles, Maria Fernanda Lopez, Veronica Torres-Banda, Claudia Cano-Ramirez, Gabriel Obregon-Molina, Gerardo Zuniga
Summary: Dendroctonus-bark beetles play important roles in forest ecosystems by colonizing and killing damaged pine trees. Research found that these beetles have an alpha-amylase capable of hydrolyzing starch, primarily active in the gut.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Food Science & Technology
Ummuhan Cakmak, Fulya Oz Tuncay, Yakup Kolcuoglu
Summary: The amylase obtained from Cladophora hutchinsiae was purified and characterized in terms of its properties and applications. The enzyme showed optimal activity at pH 6 and 10°C, and demonstrated remarkable pH stability. It could be used in the presence of certain organic solvents and cations. Additionally, the enzyme was effective in releasing reducing sugar from fruit juices and fish feed, suggesting its potential applications in various industries.
Article
Biotechnology & Applied Microbiology
Xiaodong Zhang, Caixia Li, Xuantong Chen, Chonlong Chio, Sarita Shrestha, Wensheng Qin
Summary: The study identified and characterized a high alpha-amylase producing bacterium WangLB, and cloned its alpha-amylase coding gene. The characterized BvAmylase showed good stability and activity, making it a potential candidate enzyme for industrial applications.
FERMENTATION-BASEL
(2021)
Article
Chemistry, Multidisciplinary
Asma Zafar, Ziaur Rahman, Hira Mubeen, Javairia Makhdoom, Javeria Tariq, Mahjabeen, Zulqurnain Ali, Attia Hamid, Eeza Shafique, Muhammad Nauman Aftab
Summary: This study aimed to clone and express the esterase gene from Bacillus thuringiensis and investigate its purification, stability, and activity. The results showed that the recombinant esterase enzyme had high activity, stability, and resistance, which are significant for the detergent industry.
Article
Biochemistry & Molecular Biology
E. Ataallahi, H. Naderi-Manesh, R. Roostaazad, S. Yeganeh
Summary: Purification of extracellular alpha-amylase from Bacillus subtilis was achieved through fractional precipitation by acetone and ion exchange chromatography, resulting in improved enzyme purity, activity, and stability. The optimization of operation parameters using response surface methodology was crucial in achieving high yield and purification fold.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Multidisciplinary Sciences
S. Soy, U. Lakra, P. Prakash, P. Suravajhala, V. K. Nigam, S. R. Sharma, N. Bayal
Summary: This study investigated the microbial diversity of hot springs and identified a thermophilic isolate with potential for degrading lignocellulosic agricultural waste. The isolate's enzyme production ability was analyzed and characterized.
SCIENTIFIC REPORTS
(2023)
Article
Microbiology
Shohreh Ariaeenejad, Behrouz Zolfaghari, Seyedeh Fatemeh Sadeghian Motahar, Kaveh Kavousi, Morteza Maleki, Swapnoneel Roy, Ghasem Hosseini Salekdeh
Summary: PersiAmy1, a novel alpha-amylase identified from rumen metagenomic data, showed high stability and activity under various conditions, making it a promising enzyme for diverse industrial applications such as detergent and baking industries. The enzyme demonstrated excellent resistance to extreme temperatures, pH ranges, high salinity, and various metal ions, while maintaining its enzymatic activity. It also exhibited compatibility with detergents, surfactants, and organic solvents, as well as effectiveness in stain removal and improving bread quality.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Krishna Bharwad, Satyamitra Shekh, Niraj Kumar Singh, Amrutlal Patel, Chaitanya Joshi
Summary: In this study, the full metagenome sequences from the soil of Tuwa hot-spring in Gujarat, India were examined for the presence of thermostable enzymes. The a-amylase gene was found, amplified, cloned, and expressed in Escherichia coli. The rm-a-amylase showed high activity at 60 ℃, pH 6.0, and in the presence of heavy metal ions, and it can hydrolyze agar, xylan, pectin, alginate, and cellulose.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biotechnology & Applied Microbiology
Suvasini Balasubramanian, Jun Chen, Vinoth Wigneswaran, Claus Heiner Bang-Berthelsen, Peter Ruhdal Jensen
Summary: This study focuses on improving protein production and secretion in Corynebacterium glutamicum using droplet-based microfluidic high throughput screening. Through chemical mutagenesis and DBM screening, a library of C. glutamicum secreting beta-glucosidase was generated with several mutants showing enhanced enzyme secretion capacity. Whole-genome analysis revealed specific mutations in genes associated with protein synthesis and secretion, leading to higher secretion levels of beta-glucosidase and alpha-amylase in the supernatant of the mutants. These results demonstrate the potential of DBM screening as a powerful tool for optimizing cell factories for heterologous protein production.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Adrian Sven Geissler, Annaleigh Ohrt Fehler, Line Dahl Poulsen, Enrique Gonzalez-Tortuero, Thomas Beuchert Kallehauge, Ferhat Alkan, Christian Anthon, Stefan Ernst Seemann, Michael Dolberg Rasmussen, Anne Breuener, Carsten Hjort, Jeppe Vinther, Jan Gorodkin
Summary: Fine-tuning regulatory mechanisms for gene candidates can enhance yield in cell factories. By analyzing RNA-sequencing data of alpha-amylase producing Bacillus strains, we identified numerous novel non-coding transcribed regions that undergo significant expression changes during fermentation. Knockdown experiments using CRISPRi revealed that targeting specific non-coding regions can lead to both increased and decreased yields. This study highlights the potential of non-coding RNAs as targets for improving yield in biotechnology.
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Marinela Sokarda Slavic, Milan Kojic, Aleksandra Margetic, Nemanja Stanisavljevic, Lazar Gardijan, Natasa Bozic, Zoran Vujcic
Summary: Amylase from thermophilic bacterial strain Anoxybacillus vranjensis ST4 was cloned, expressed, and purified successfully. The enzyme showed maximum activity at 60-80°C and was active and stable over a wide pH range (4.0-9.0). It efficiently hydrolyzed starch granules, releasing maltose, maltotriose, and maltopentaose as the main products. These findings indicate that this highly stable and versatile enzyme has great potential for industrial applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Biochemistry & Molecular Biology
Ilya Lyagin, Aysel Aslanli, Maksim Domnin, Nikolay Stepanov, Olga Senko, Olga Maslova, Elena Efremenko
Summary: Active research is being conducted on metal-containing compounds and enzymes as effective antifungal agents to tackle the increasing antifungal resistance problem. Metals are of interest due to the variety of ligands that can be used, including chemically synthesized and naturally obtained variants. The main antifungal mechanism of metals is the generation and accumulation of reactive oxygen species (ROS). Hydrolytic enzymes, such as glucanases and proteases, exhibit antifungal properties by affecting various elements of fungal cells and proteins responsible for biofilm formation. This review discusses the potential of combining metals and enzymes as antifungal agents and explores the possible interactions between metals and enzymes, and proteins and metal-containing compounds.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Physical
Scheherazed Dakhmouche Djekrif, Leila Bennamoun, Fatima Zohra Kenza Labbani, Amel Ait Kaki, Tahar Nouadri, Andre Pauss, Zahia Meraihi, Louisa Gillmann
Summary: The study showed that alpha-amylase and pullulanase from Clavispora lusitaniae ABS7 isolated from wheat seeds exhibited high activity and stability, making them suitable for industrial applications such as detergents.
Article
Engineering, Chemical
Mauro Marengo, Davide Pezzilli, Eleonora Gianquinto, Alex Fissore, Simonetta Oliaro-Bosso, Barbara Sgorbini, Francesca Spyrakis, Salvatore Adinolfi
Summary: Alpha-amylases are enzymes with a wide distribution and high sequence identity, but their catalytic activities have diverged throughout evolution. By comparing alpha-amylases from human, Aspergillus oryzae, and pancreatic porcine, we found that despite structural homology, these enzymes exhibit strikingly different activities mediated by different ions. This highlights the need to carefully consider these functional differences and establish proper experimental conditions when using alpha-amylases from different organisms as models for human enzymes.
Article
Agriculture, Multidisciplinary
Wenxian Liu, Shizhe Tang, Jing Peng, Lina Pan, Jiaqi Wang, Haina Cheng, Zhu Chen, Yuguang Wang, Hongbo Zhou
Summary: This study improved the soluble expression and enzyme activity of α-1,2-fucosyltransferases using a combinatorial engineering strategy, addressing the challenges in the biosynthesis of 2'-FL.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2022)
Article
Energy & Fuels
Zahra Azzouz, Azzeddine Bettache, Ibtissem Djinni, Nawel Boucherba, Said Benallaoua
Summary: In this study, xylanase production from Aspergillus niger strain BG was achieved through solid-state fermentation. The effects of various factors on xylanase production were optimized using the OFAT and RSM methods. The optimum conditions for maximum xylanase production were determined using mathematical models and analysis of variance.
BIOMASS CONVERSION AND BIOREFINERY
(2022)
Article
Biochemistry & Molecular Biology
Amel Dahdouh, Nawel Boucherba, Khelifa Bouacem, Sondes Mechri, Adel Amirouche, Ali Aksas, Bassem Jaouadi, Djamel Edine Kati
Summary: The study purified a plant peroxidase TRP from turnip roots and characterized its biochemical properties, revealing high catalytic efficiency and antioxidant activities, indicating its potential application in enzyme therapy for the pharmaceutical and medicinal industries.
BIOCATALYSIS AND BIOTRANSFORMATION
(2022)
Article
Biochemistry & Molecular Biology
Khelifa Bouacem, Fawzi Allala, Nadia Zarai Jaouadi, Sondes Hamdi, Sondes Mechri, Kahina Ighilahriz, Hatem Rekik, Hocine Hacene, Amel Bouanane-Darenfed, Bassem Jaouadi
Summary: A novel extracellular lignin peroxidase (LiP PR40) was produced by a white-rot Agaricomycetes fungus strain newly isolated from dead deciduous trees in Algeria. This purified enzyme showed premium activity at pH 3 and 80 degrees C, and exhibited higher catalytic efficiency and dye-decolorisation aptitude compared to commercial horseradish peroxidase and reported LiP BA45. These properties make LiP PR40 a potential candidate for destaining synthetic dyes and lignin biodegradation.
BIOCATALYSIS AND BIOTRANSFORMATION
(2022)
Article
Biotechnology & Applied Microbiology
Rima Maibeche, Nawel Boucherba, Kamel Bendjeddou, Alaric Prins, Cilia Bouiche, Samir Hamma, Mohammed Benhoula, Zahra Azzouz, Azzeddine Bettache, Said Benallaoua, Marilize Le Roes-Hill
Summary: Unique environments are important sources of novel microorganisms and novel chemistries. In this study, novel peroxidase-producing actinobacterial strains were isolated from telluric samples collected from different regions of Algeria. The isolated strains, mainly belonging to the genus Streptomyces, showed optimal peroxidase production under specific cultivation conditions. The purified peroxidase fraction from one selected strain exhibited potential biotechnological applications.
INTERNATIONAL MICROBIOLOGY
(2022)
Article
Chemistry, Applied
Sondes Mechri, Khelifa Bouacem, Taha-Bilel Chalbi, Marwa Khaled, Fawzi Allala, Amel Bouanane-Darenfed, Hocine Hacene, Bassem Jaouadi
Summary: This study focuses on the protease production and characteristics of a strain called TN-X30, identified as Streptomyces mutabilis. The researchers found that optimizing the culture conditions and using lyophilization techniques improved the protease yield and stability. The TN-X30 protease showed excellent performance in detergent formulations, reducing potential environmental chemical threats.
JOURNAL OF SURFACTANTS AND DETERGENTS
(2022)
Article
Biochemistry & Molecular Biology
Ismail Hasnaoui, Ahlem Dab, Sondes Mechri, Houssam Abouloifa, Ennouamane Saalaoui, Bassem Jaouadi, Alexandre Noiriel, Abdeslam Asehraou, Abdelkarim Abousalham
Summary: A novel extracellular lipase P22 from Penicillium crustosum Thom was isolated and characterized. The specific activities of P22 lipase were found to be 5000 and 10,000 U/mg on olive oil and trioctanoin emulsions, respectively. It exhibited clear regioselectivity toward the sn-1 position of surface-coated triglycerides and showed high activity and stability in the presence of water-immiscible organic solvents, surfactants, and oxidizing agents. It also showed compatibility with commercial laundry detergents and effectively removed oil stains.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Sondes Hamdi, Fawzi Allala, Sondes Mechri, Khelifa Bouacem, Hatem Rekik, Hocine Hacene, Bassem Jaouadi, Marilize Le Roes-Hill, Nadia Zarai Jaouadi
Summary: Textile dyes in wastewater from textile factories pose a significant environmental problem, threatening aquatic life. In this study, a novel enzyme called MnP AN30 was found to effectively decolorize various textile dyes with high efficiency. The gene encoding this enzyme was cloned and expressed, and the recombinant enzyme showed similar biochemical properties to the native enzyme. This research provides a potential candidate for the biological treatment and decolorization of synthetic textile dyes.
PROCESS BIOCHEMISTRY
(2022)
Article
Food Science & Technology
Ourdia-Nouara Kernou, Zahra Azzouz, Amine Belbahi, Kamelia Kerdouche, Ghania Kaanin-Boudraa, Akila Amir, Khodir Madani, Patricia Rijo
Summary: This study focused on the inactivation of Escherichia coli in an orange juice drink using a combined microwave-ultrasound system. The results showed that the combination treatment was more effective than individual treatments in eliminating the bacteria. The optimal treatment conditions were determined as 900 W microwave power, 33 s microwave treatment time, and 20 min time of ultrasound.
Review
Biochemistry & Molecular Biology
Ourdia-Nouara Kernou, Zahra Azzouz, Khodir Madani, Patricia Rijo
Summary: The emergence of antimicrobial resistance and the harmful consequences of antibiotic use have led to the need for innovative antimicrobial therapies, with natural substances being considered a promising alternative. Rosmarinic acid, a compound derived from rosemary, has shown great potential as an antimicrobial agent against various microorganisms. Its derivatives have also been chemically synthesized and proven to be effective against microbial pathogens. This review explores the antimicrobial effects and mechanisms of rosmarinic acid and its derivatives, both alone and in combination with other antimicrobial agents.
Article
Multidisciplinary Sciences
Ahlem Dab, Ismail Hasnaoui, Sondes Mechri, Fawzi Allala, Khelifa Bouacem, Alexandre Noiriel, Amel Bouanane-Darenfed, Ennouamane Saalaoui, Abdeslam Asehraou, Fanghua Wang, Abdelkarim Abousalham, Bassem Jaouadi
Summary: This study describes a newly isolated extracellular lipolytic carboxylester hydrolase called FAL from a filamentous fungus. FAL exhibited lipase and PLA(1) activities, and showed high tolerance to various organic solvents, surfactants, and oxidants. It also demonstrated effective oil-stain removal in laundry detergents, suggesting potential applications in the detergent industry.
Article
Energy & Fuels
Mohammed Benhoula, Zahra Azzouz, Azzeddine Bettache, Marilize Le Roes-Hill, Warda Djoudi, Rima Maibeche, Samir Hamma, Mohamed Sabri Bensaad, Zahir Amghar, Aya Boudjelal, Said Benallaoua, Nawel Boucherba
Summary: This study isolated actinobacteria capable of producing extracellular lipases using olive mill wastewater (OMW) as the sole carbon source. The production of lipase was optimized using response surface methodology, and the optimal conditions were found to be incubation for 9 days at pH 4, with an inoculum size of 1.7x10(7) spores/mL, incubated at 30 degrees C using 6% (v/v) OMW.
BIOMASS CONVERSION AND BIOREFINERY
(2023)
Review
Biology
Cilia Bouiche, Aicha Asma Houfani, Zahra Azzouz, Lamia Taouzinet, Lamia Medouni-Haroune, Meriem Amrane-Abider, Khodir Madani
Summary: This paper reviews the current status of lignocellulosic pretreatments and the CAZymes hydrolysis of xylan, exploring previously reported alternatives and enzymes. Evaluation criteria and parameters for XOS production processes, which can differ significantly between studies, are also discussed. However, most commonly, XOS are produced in two stages through acid pretreatment and enzymatic hydrolysis. This two-stage process is highly effective and yields a nutrient-rich product that is beneficial for various purposes.
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
