标题
Pathological mTOR mutations impact cortical development
作者
关键词
-
出版物
HUMAN MOLECULAR GENETICS
Volume -, Issue -, Pages -
出版商
Oxford University Press (OUP)
发表日期
2019-02-21
DOI
10.1093/hmg/ddz042
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination
- (2018) Sang Min Park et al. NEURON
- Cerebral cortex development: an outside-in perspective
- (2017) Gulistan Agirman et al. FEBS LETTERS
- TFEB activation restores migration ability to Tsc1-deficient adult neural stem/progenitor cells
- (2017) Alessandro Magini et al. HUMAN MOLECULAR GENETICS
- Molecular neurobiology of mTOR
- (2017) Katarzyna Switon et al. NEUROSCIENCE
- Somatic Mutations Activating the mTOR Pathway in Dorsal Telencephalic Progenitors Cause a Continuum of Cortical Dysplasias
- (2017) Alissa M. D’Gama et al. Cell Reports
- Malformations of cortical development
- (2016) Rahul S. Desikan et al. ANNALS OF NEUROLOGY
- Tuberous sclerosis complex: From molecular biology to novel therapeutic approaches
- (2016) Katarzyna Switon et al. IUBMB LIFE
- Targeted in vivo genetic manipulation of the mouse or rat brain by in utero electroporation with a triple-electrode probe
- (2016) Joanna Szczurkowska et al. Nature Protocols
- Association ofMTORMutations With Developmental Brain Disorders, Including Megalencephaly, Focal Cortical Dysplasia, and Pigmentary Mosaicism
- (2016) Ghayda M. Mirzaa et al. JAMA Neurology
- Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy
- (2015) Jae Seok Lim et al. NATURE MEDICINE
- Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex
- (2015) Uk Yeol Moon et al. Cell Reports
- A Diverse Array of Cancer-Associated MTOR Mutations Are Hyperactivating and Can Predict Rapamycin Sensitivity
- (2014) B. C. Grabiner et al. Cancer Discovery
- Selective Activation of mTORC1 Signaling Recapitulates Microcephaly, Tuberous Sclerosis, and Neurodegenerative Diseases
- (2014) Hidetoshi Kassai et al. Cell Reports
- Hemimegalencephaly, a paradigm for somatic postzygotic neurodevelopmental disorders
- (2013) Seung Tae Baek et al. CURRENT OPINION IN NEUROLOGY
- A circuitry and biochemical basis for tuberous sclerosis symptoms: from epilepsy to neurocognitive deficits
- (2013) David M. Feliciano et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- mTORC1 Targets the Translational Repressor 4E-BP2, but Not S6 Kinase 1/2, to Regulate Neural Stem Cell Self-Renewal In Vivo
- (2013) Nathaniel W. Hartman et al. Cell Reports
- Pten deletion causes mTorc1-dependent ectopic neuroblast differentiation without causing uniform migration defects
- (2012) G. Zhu et al. DEVELOPMENT
- Sustained Activation of mTOR Pathway in Embryonic Neural Stem Cells Leads to Development of Tuberous Sclerosis Complex-Associated Lesions
- (2011) Laura Magri et al. Cell Stem Cell
- Non-canonical functions of the tuberous sclerosis complex-Rheb signalling axis
- (2011) Nicole A. Neuman et al. EMBO Molecular Medicine
- Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle
- (2011) J. Zhou et al. GENES & DEVELOPMENT
- Single-cell Tsc1 knockout during corticogenesis generates tuber-like lesions and reduces seizure threshold in mice
- (2011) David M. Feliciano et al. JOURNAL OF CLINICAL INVESTIGATION
- Zipcode Binding Protein 1 Regulates the Development of Dendritic Arbors in Hippocampal Neurons
- (2011) M. Perycz et al. JOURNAL OF NEUROSCIENCE
- Single amino-acid changes that confer constitutive activation of mTOR are discovered in human cancer
- (2010) T Sato et al. ONCOGENE
- Isolation of Hyperactive Mutants of Mammalian Target of Rapamycin
- (2008) Yoichiro Ohne et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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