Article
Fisheries
Eric Guevelou, Ryan B. Carnegie, Laura Whitefleet-Smith, Jessica Moss Small, Standish K. Allen
Summary: NIR spectroscopy technology shows promise as an alternative method for quantitatively detecting P. marinus infection in eastern oysters, offering valuable insights into oyster condition and resistance to the problematic parasite.
Article
Environmental Sciences
Kaili M. Gregory, Katherine McFarland, Matthew P. Hare
Summary: Low salinity has negative effects on reproduction in estuarine bivalves. It delays gametogenesis and spawning in oysters, except in June when low salinity promotes earlier gametogenesis. The findings suggest that low salinity not only affects the timing of reproduction but also extends the reproductive season.
ESTUARIES AND COASTS
(2023)
Article
Genetics & Heredity
Jiulin Chan, Lu Wang, Li Li, Kang Mu, David Bushek, Yue Xu, Ximing Guo, Guofan Zhang, Linlin Zhang
Summary: Infectious disease outbreaks are causing declines in marine invertebrates, with the Eastern oyster being susceptible to Dermo while the Pacific oyster is resistant due to differences in their immune responses. Transcriptomic responses to the parasite showed differences in immune gene families and potential coevolution between the two oyster species.
FRONTIERS IN GENETICS
(2021)
Article
Zoology
Selio Souza da Rocha, Rachel Costa Sabry, Rafael dos Santos Rocha, Rodrigo Maggioni, Bruno Vinicius Silva de Araujo, Renata Julia dos Santos Silva, Joao Marcelo Azevedo de Paula Antunes
Summary: This study detects the presence of P. marinus in oysters for the first time in the estuaries of the Potengi River and the Guarairas lagoon in Brazil using qPCR as a diagnostic tool.
JOURNAL OF INVERTEBRATE PATHOLOGY
(2023)
Article
Fisheries
Jessica L. Piesz, Abigail K. Scro, Ryan Corbett, Kathryn Markey Lundgren, Roxanna Smolowitz, Marta Gomez-Chiarri
Summary: The developed multiplex qPCR assay can simultaneously detect three parasites in eastern oysters with high efficiency and sensitivity on different platforms.
DISEASES OF AQUATIC ORGANISMS
(2022)
Review
Biochemistry & Molecular Biology
Noora Barzkar, Zahoor Khan, Saeid Tamadoni Jahromi, Sajjad Pourmozaffar, Mohsen Gozari, Reza Nahavandi
Summary: Marine organisms are valuable sources of enzymes and their inhibitors with great therapeutic potential, particularly serine proteases and their inhibitors showing promise in biomedical applications. The uncontrolled activity of these proteases can lead to diseases, but their actions are regulated by serine protease inhibitors to maintain physiological functions.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Fisheries
Laura K. Solinger, Kathy A. Ashton-Alcox, Eric N. Powell, Kathleen M. Hemeon, Sara M. Pace, Thomas M. Soniat, Leanne M. Poussard
Summary: This study estimates the maximum sustainable yield (MSY) of the eastern oyster in the Delaware Bay using simulation analysis and a spawning stock model. It provides rebuilding goals for the oyster fishery and reef management.
CANADIAN JOURNAL OF FISHERIES AND AQUATIC SCIENCES
(2022)
Article
Parasitology
Fei Wu, Hui Zhang, Jingru Zhou, Jie Wu, Danni Tong, Xueqiu Chen, Yan Huang, Hengzhi Shi, Yi Yang, Guangxu Ma, Chaoqun Yao, Aifang Du
Summary: The study found that Haemonchus contortus interferes with the host's coagulation mechanism through Hc-SPI-I8A to facilitate blood-sucking and digestion, contributing to successful parasitism. This provides important insights for drug discovery and vaccine development against this significant parasite.
INTERNATIONAL JOURNAL FOR PARASITOLOGY
(2021)
Review
Medicine, Research & Experimental
E. Burchacka, P. Pieta, A. Lupicka-Slowik
Summary: There are four types of antifungal drugs targeting different aspects of fungi, but increasing resistance poses a challenge to treatment options. Thus, developing new drug strategies is crucial for addressing fungal diseases effectively.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Infectious Diseases
Terry F. Plasse, Belkis Delgado, Jeffrey Potts, Danielle Abramson, Clara Fehrmann, Reza Fathi, Grace A. McComsey
Summary: This pilot study evaluated the efficacy of serine protease inhibitor upamostat in patients with symptomatic COVID-19. The results showed that compared to the placebo group, the upamostat group had a shorter time to sustained symptom recovery and a significant reduction in new severe symptoms and hospitalization. The study suggests the potential clinical significance of upamostat in the treatment of COVID-19.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Immunology
Xin Zhang, Miao Li, Layla El Moussawi, Sally Saab, Shasha Zhang, Mike A. Osta, Kristin Michel
Summary: Humoral immune responses in animals are tightly controlled by regulated proteolysis, where extracellular protease cascades activate key immune proteins and enzymes. In mosquitoes, the protease network regulates melanization reactions and affects resistance against microorganisms.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Multidisciplinary Sciences
Andreza do Socorro Silva da Veiga, Fernando Tobias Silveira, Edilene Oliveira da Silva, Jose Antonio Picanco Diniz Junior, Sanderson Correa Araujo, Marliane Batista Campos, Andrey Moacir do Rosario Marinho, Geraldo Celio Brandao, Valdicley Vieira Vale, Sandro Percario, Maria Fani Dolabela
Summary: This study evaluated the morphological changes caused by fractions and subfractions obtained from barks of Aspidosperna nitidum against L. (L.) amazonensis promastigotes. The results suggest that alkaloids isolated from A. nitidum show potential as leishmanicidal agents. Scanning electron microscopy and transmission electron microscopy analysis revealed changes in the parasites' morphology after treatment with the active fractions.
SCIENTIFIC REPORTS
(2022)
Article
Biology
Harrison J. F. Eyck, Gregory P. Brown, Lee A. Rollins, Richard Shine
Summary: This study investigates a host-parasite system and finds differences in host resistance between different populations. The chemical cues from toad skin altered parasite behavior, but the number of infection attempts did not differ between populations. The success rate of infection was higher for the range-edge toads, indicating that their lower resistance is due to less effective immune defenses.
Article
Biotechnology & Applied Microbiology
Zongchao Chen, Pengfei Niu, Xiaomei Ren, Wenlong Han, Ruyu Shen, Min Zhu, Yang Yu, Chan Ding, Shengqing Yu
Summary: Recent studies have shown that the secreted subtilisin-like serine protease SspA in Riemerella anatipestifer is associated with bacterial virulence, proteolysis, and functions as an effector protein of the T9SS system, playing a crucial role in pathogenesis and host evasion.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2022)
Article
Microbiology
Elin Einarsson, Imen Lassadi, Jana Zielinski, Qingtian Guan, Tobias Wyler, Arnab Pain, Sebastian G. Gornik, Ross F. Waller
Summary: This study expanded the genetic tools for Perkinsus by constructing a modular plasmid assembly system, developing efficient selection systems, identifying genomic integration patterns, and using bi-cistronic transcripts. These new tools enhance the capacity to genetically modify and study Perkinsus as an aquatic parasite and evolutionary model.
Article
Fisheries
Huahui Chen, Miao Lv, Zhimeng Lv, Chenghua Li, Wei Xu, Weiwei Zhang, Xuelin Zhao, Xuemei Duan, Chunhua Jin
FISH & SHELLFISH IMMUNOLOGY
(2017)
Article
Oncology
Wei Xu, Britany A. Foster, Mackenzie Richards, Keneth R. Bondioli, Girish Shah, Christopher C. Gren
INTERNATIONAL JOURNAL OF ONCOLOGY
(2018)
Article
Fisheries
Shuxia Xue, Jinsheng Sun, Wei Xu
JOURNAL OF THE WORLD AQUACULTURE SOCIETY
(2018)
Article
Environmental Sciences
Wei Xu, Emily N. Vebrosky, Mackenzie L. Richards, Kevin L. Armbrust
SCIENCE OF THE TOTAL ENVIRONMENT
(2018)
Article
Environmental Sciences
Wei Xu, Emily N. Vebrosky, Kevin L. Armbrust
ENVIRONMENT INTERNATIONAL
(2018)
Article
Environmental Sciences
A. Bonisoli-Alquati, W. Xu, P. C. Stouffer, S. S. Taylor
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Biochemistry & Molecular Biology
Wei Xu, Elodi Dielubanza, Amanda Maisel, Kai Leung, Thomas Mustoe, Seok Hong, Robert Galiano
Summary: Chronic wounds are often caused by bacterial contamination, with Staphylococcus aureus being a common strain. Inhibition of keratinocyte migration by S. aureus exudate may involve the upregulation of connexin-43 (Cx43). The treatment of bacterium-infected wounds may be improved by targeting Cx43 and Akt to overcome wound closure impairment.
CELLULAR AND MOLECULAR LIFE SCIENCES
(2021)
Article
Engineering, Environmental
Wei Xu, Emily N. Vebrosky, Kevin L. Armbrust
JOURNAL OF HAZARDOUS MATERIALS
(2020)
Review
Physiology
Nin Gan, Leisha Martin, Wei Xu
Summary: The past decade has seen an increase in research on the effects of crude oil chemicals, such as PAHs, on marine organisms, with oysters being a focus due to their susceptibility to contaminants. PAHs readily bioaccumulate in oysters' soft tissues and lead to negative effects such as changed gene expression, reduced DNA integrity, and abnormal larval growth. Additional stressors like temperature changes and acidification may exacerbate the negative effects of PAH exposure, while shorter-term salinity changes may reduce PAH exposure effects.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Environmental Sciences
Leisha M. A. Martin, Nin Gan, Erica Wang, Mackenzie Merrill, Wei Xu
Summary: Nanoplastics research aims to assess the risk of exposure to nanoparticles in the environment. Current studies utilize surface-modified polymers like polystyrene as models, but further investigation is needed to understand the effects of surface engineering and solvent properties on results.
ENVIRONMENTAL POLLUTION
(2022)
Article
Materials Science, Multidisciplinary
Leisha Martin, Jian Sheng, Nattamai Bhuvanesh, Maryam Jalali-Mousavi, Wei Xu
Summary: Nanoparticles that can be optically tracked are of interest for biodistribution studies, but using dyes or fluorophores may result in optical artifacts and affect other properties. We produced ZnO nanoparticles with different morphologies and defect emissions, which have broad applications.
Article
Fisheries
Wei Xu, Charles Greg Lutz, Christopher M. Taylor, Miriam Contin Ortega
Summary: The study aimed to identify low-cost prebiotic compounds that could enhance the absorption of food nutrients by fish, with XOS and GOS significantly reducing the feed conversion ratio in 30-day-old and 90-day-old Nile tilapia. The application of XOS and GOS supplements also improved antioxidation processes and led to significant changes in the fish gut microbiota.
AQUACULTURE NUTRITION
(2022)
Article
Nanoscience & Nanotechnology
Yin Liu, Jiao Wang, Jian Zhang, Sandra Marbach, Wei Xu, Lin Zhu
ACS APPLIED MATERIALS & INTERFACES
(2020)
Article
Environmental Sciences
Mackenzie Richards, Wei Xu, Amy Mallozzi, Reagan M. Errera, John Supan
FRONTIERS IN MARINE SCIENCE
(2018)