Article
Multidisciplinary Sciences
Jeffrey P. Bibeau, Nandan G. Pandit, Shawn Gray, Nooshin Shatery Nejad, Charles V. Sindelar, Wenxiang Cao, Enrique M. De la Cruza
Summary: The bending and twisting mechanics of actin filaments dictate the generation, sensing, and adaptation of actin cytoskeleton force. This study used magnetic tweezers and microfluidics to twist and pull individual actin filaments and evaluate their response to applied loads. Twisted filaments adopted a supercoiled plectoneme to bend and dissipate torsional strain, while pulling prevented plectoneme formation and caused filament severing. The study also found that filament severing by cofilin was driven by local twist strain at boundaries between bare and decorated segments and accelerated by low pN pulling forces. It demonstrates the importance of filament twisting in the regulation of actin filament stability and assembly dynamics.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Obstetrics & Gynecology
Y. Bart, A. Mohr-Sasson, S. Yousefi, M. Goldenberg, R. Meyer, S. Toussia-Cohen, Y. Eyal, S. Mazaki-Tovi, R. Mashiach
Summary: The study revealed a positive association between adnexal twist degree and the risk of torsion recurrence.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2021)
Review
Cardiac & Cardiovascular Systems
Pedro L. Valenzuela, Luis M. Ruilope, Alejandro Santos-Lozano, Matthias Wilhelm, Nicolle Kraenkel, Carmen Fiuza-Luces, Alejandro Lucia
Summary: There is a parallel between the pandemic of physical inactivity and the prevalence of cardiovascular disease. Regular physical activity and exercise can prevent and manage cardiovascular disease by improving metabolic health, reducing inflammation, and promoting cardiovascular adaptations. This review discusses the cardiovascular effects of physical activity and exercise, as well as the safe implementation in patients with cardiovascular disease.
EUROPEAN HEART JOURNAL
(2023)
Article
Optics
Bingsen Huang, Xinzhi Sheng, Jiaqi Cao, Wei Gao, Shuqin Liou
Summary: This paper proposes and experimentally demonstrates a high sensitivity optical fiber twist sensor based on Suspend Core Fiber Sagnac Interference (SCFSI). By filling the air hole of the Suspend Core Fiber (SCF) with alcohol, the twist sensitivity of the sensor is greatly improved. The sensor also exhibits a capability of temperature calibration, making it suitable for structural health monitoring applications.
Review
Hospitality, Leisure, Sport & Tourism
Yihua Bei, Lei Wang, Rongjing Ding, Lin Che, Zhiqing Fan, Wei Gao, Qi Liang, Shenghui Lin, Suixin Liu, Xiao Lu, Yuqin Shen, Guifu Wu, Jian Yang, Guolin Zhang, Wei Zhao, Lan Guo, Junjie Xiao
Summary: Exercise has been shown to be an effective way to promote cardiovascular health, but more research is needed to understand the underlying mechanisms. Standardized procedures and well-established evaluation indicators for animal exercise models are essential for conducting effective studies to prevent and treat cardiovascular diseases.
JOURNAL OF SPORT AND HEALTH SCIENCE
(2021)
Article
Psychology, Multidisciplinary
Stefan Tino Kulnik, Mahdi Sareban, Isabel Hoeppchen, Silke Droese, Andreas Egger, Johanna Gutenberg, Barbara Mayr, Bernhard Reich, Daniela Wurhofer, Josef Niebauer
Summary: This study aimed to assess the impact of the closure of group-based cardiac rehabilitation (CR) training during the first COVID-19 lockdown on patients' physical activity, cardiorespiratory fitness, and cardiovascular risk, and to describe the patient experience of lockdown and home-based exercise training. The study found that exercise capacity significantly reduced after the lockdown, but there was no significant difference in cardiovascular risk factors. Qualitative data showed that many patients missed the weekly CR training and felt less confident to carry out home-based exercise training without professional supervision.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Engineering, Marine
Da Cui, Daokui Li, Shiming Zhou
Summary: This paper proposes a box structure design based on the extension-twist multicoupled laminates for wind turbine blades, which can effectively solve the problems of easy damage and fracture of the blades and unstable power output under strong wind conditions. By optimizing the design of the multicoupled laminates and box structure, the extension-twist coupling and bend-twist coupling are enhanced, and the feasibility of the design is verified through numerical simulation.
Review
Cell Biology
Sibo Liu, Yuhe Liu, Zhihan Liu, Yansong Hu, Meixiu Jiang
Summary: Atherosclerosis, a chronic inflammatory vascular disease, is a major pathological basis of coronary heart disease. The incidence of atherosclerosis has been increasing due to changes in people's lifestyles and diets. Physical activity and exercise training have been found to be effective strategies for reducing cardiovascular disease risk. However, the optimal exercise mode for improving risk factors related to atherosclerosis is still unclear.
JOURNAL OF CELLULAR PHYSIOLOGY
(2023)
Article
Mathematics, Applied
Anna Florio, Patrice Le Calvez
Summary: In this paper, we provide sufficient conditions to ensure the existence of a set of positive measure of points with non-zero asymptotic torsion for a twist map f of the annulus preserving the Lebesgue measure. It is deduced that every bounded instability region for f contains a set of positive measure of points with non-zero asymptotic torsion. Furthermore, for an exact symplectic twist map f, we offer a simple, geometric proof of a result characterizing C-0-integrability of f by the absence of conjugate points, originally shown by Cheng and Sun in 1996.
Review
Cardiac & Cardiovascular Systems
Gerard D'Onofrio, Jonathan Kirschner, Heidi Prather, David Goldman, Alan Rozanski
Summary: Resistance training is often overlooked but essential for physical health. As we age, our musculoskeletal system declines, resulting in loss of muscle strength, flexibility, and balance. Resistance training can help reduce joint stress, improve muscle mass and strength, increase metabolism and bone density, reduce body fat and cardiac risk factors, and enhance cognitive function and psychological well-being.
PROGRESS IN CARDIOVASCULAR DISEASES
(2023)
Article
Cardiac & Cardiovascular Systems
Yasina B. Somani, Laween Uthman, Vincent L. Aengevaeren, Laura Rodwell, Gregory Y. H. Lip, Maria T. E. Hopman, Niels Van Royen, Thijs M. H. Eijsvogels, Dick H. J. Thijssen
Summary: Prolonged exercise can lead to the release of cardiac troponin. The magnitude of troponin release decreases with successive days of exercise in healthy individuals and those with cardiovascular risk factors, but not in patients with established cardiovascular disease.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2023)
Article
Sport Sciences
Chen Zheng, Jason M. R. Gill, Feng Hua Sun, Wendy Yajun Huang, Sinead Sheridan, Xiang-Ke Chen, Yalan Wu, Chun-Kwok Wong, Xiao Yu Tian, Stephen Heung-Sang Wong
Summary: Increasing daily physical activity is an effective way to reduce the risk of cardiometabolic diseases. This study compared the effects of increasing light physical activity (LPA) and moderate-to-vigorous physical activity (MVPA) on cardiometabolic markers in Chinese adults with obesity. The results showed that MVPA had more positive effects on body composition and cardiometabolic biomarkers compared to LPA.
JOURNAL OF SPORTS SCIENCES
(2023)
Article
Clinical Neurology
Mauro F. F. Mediano, Yejin Mok, Josef Coresh, Anna Kucharska-Newton, Priya Palta, Kamakshi Lakshminarayan, Wayne D. Rosamond, Kunihiro Matsushita, Silvia Koton
Summary: Higher levels of total prestroke physical activity, as well as work and leisure activities, are associated with a lower risk of mortality after incident stroke. It is suggested that promoting physical activity throughout life could be beneficial in reducing long-term mortality post-stroke.
Review
Materials Science, Multidisciplinary
Hiba Azzeddine, Djamel Bradai, Thierry Baudin, Terence G. Langdon
Summary: This study focuses on the influence of various factors such as imposed strain, deformation temperature, and alloying elements on the crystallographic texture evolution in FCC, BCC, and HCP crystal structure materials processed exclusively by HPT.
PROGRESS IN MATERIALS SCIENCE
(2022)
Article
Urology & Nephrology
Matthew P. M. Graham-Brown, Daniel S. March, Robin Young, Patrick J. Highton, Hannah M. L. Young, Darren R. Churchward, Maurice Dungey, David J. Stensel, Nicolette C. Bishop, Nigel J. Brunskill, Alice C. Smith, Gerry P. McCann, Alex McConnachie, James O. Burton
Summary: Intradialytic cycling program reduces left ventricular mass and mitigates cardiovascular disease risk factors for hemodialysis patients. The intervention also shows significant improvements in heart health parameters with no increased risk of arrhythmias.
KIDNEY INTERNATIONAL
(2021)
Article
Sport Sciences
Mike Stembridge, Philip N. Ainslie, Rob Shave
EUROPEAN JOURNAL OF SPORT SCIENCE
(2016)
Article
Cardiac & Cardiovascular Systems
Alexandra M. Williams, Rob E. Shave, Mike Stembridge, Neil D. Eves
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2016)
Article
Cardiac & Cardiovascular Systems
Mike Stembridge, Philip N. Ainslie, Joseph Donnelly, Nicholas T. MacLeod, Suchita Joshi, Michael G. Hughes, Kami Sherpa, Rob Shave
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2016)
Article
Cardiac & Cardiovascular Systems
Victoria L. Meah, John R. Cockcroft, Karianne Backx, Rob Shave, Eric J. Stoehr
Review
Sport Sciences
Jane M. Black, Eric J. Stoehr, Rob Shave, Joseph I. Esformes
JOURNAL OF SCIENCE AND MEDICINE IN SPORT
(2016)
Article
Veterinary Sciences
D. Dickson, R. Shave, M. Rishniw, J. Harris, M. Patteson
JOURNAL OF SMALL ANIMAL PRACTICE
(2016)
Article
Cardiac & Cardiovascular Systems
Rachel Lord, Keith George, John Somauroo, Mike Stembridge, Nikhil Jain, Martin D. Hoffman, Rob Shave, Francois Haddad, Euan Ashley, Helen Jones, David Oxborough
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
(2016)
Article
Clinical Neurology
R. S. Gibbons, C. G. Stock, B. J. Andrews, A. Gall, R. E. Shave
Article
Medicine, General & Internal
Maria C. Kearney, Eve Gallop-Evans, John R. Cockcroft, Eric J. Stohr, Eveline Lee, Karianne Backx, Mark Haykowsky, Zaheer Yousef, Rob Shave
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2017)
Article
Neurosciences
Mike Stembridge, Philip N. Ainslie, Lindsey M. Boulet, James Anholm, Prajan Subedi, Michael M. Tymko, Christopher K. Willie, Stephen-Mark Cooper, Rob Shave
JOURNAL OF PHYSIOLOGY-LONDON
(2019)
Article
Cardiac & Cardiovascular Systems
Tony G. Dawkins, Bryony A. Curry, Stephen P. Wright, Victoria L. Meah, Zaheer Yousef, Neil D. Eves, Rob E. Shave, Michael Stembridge
Summary: This meta-analysis found that athletes have significantly higher RV pressure, increased tricuspid annular displacement and velocity, as well as increased longitudinal apical strain compared to controls.
CIRCULATION-CARDIOVASCULAR IMAGING
(2021)
Article
Physiology
Denis J. Wakeham, Tony G. Dawkins, Rachel N. Lord, Jack S. Talbot, Freya M. Lodge, Bryony A. Curry, Lydia L. Simpson, Christopher J. A. Pugh, Robert E. Shave, Jonathan P. Moore
Summary: The study aimed to determine the effects of habitual endurance exercise and age on aortic haemodynamics and assess the relationship between muscle sympathetic nerve activity and blood pressure in men. The results showed that, compared to nonrunners, young runners had lower systolic blood pressure, while there were no significant differences in aortic pulse wave velocity and augmentation pressure between runners and nonrunners. In addition, there was no correlation between peripheral sympathetic vasomotor outflow and blood pressure in both young and middle-aged men.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Physiology
Tony G. Dawkins, Bryony A. Curry, Aimee L. Drane, Rachel N. Lord, Cory T. Richards, Freya M. Lodge, Zaheer Yousef, Christopher J. A. Pugh, Robert E. Shave, Mike Stembridge
Summary: The study found that endurance athletes have increased longitudinal strain at the base of the RV in response to haemodynamic volume challenges, while non-athletic control subjects have lower strain. Training-induced cardiac remodelling may involve region-specific adaptation in the RV functional response to volume manipulation, indicating a greater functional reserve capacity in endurance athletes.
EXPERIMENTAL PHYSIOLOGY
(2022)
Article
Rehabilitation
Gordon McGregor, David Gaze, David Oxborough, Jamie O'Driscoll, Rob Shave
EUROPEAN JOURNAL OF PHYSICAL AND REHABILITATION MEDICINE
(2016)