Cardiac Sirt1 mediates the cardioprotective effect of caloric restriction by suppressing local complement system activation after ischemia-reperfusion

Cardioprotective mIGF-1/SIRT1 signaling induces hypertension, leukocytosis and fear response in mice

(2016) Giulia Bolasco et al.   Aging-US

Indispensable role of endothelial nitric oxide synthase in caloric restriction-induced cardioprotection against ischemia-reperfusion injury

(2015) Ken Shinmura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Modulating effect of SIRT1 activation induced by resveratrol on Foxo1-associated apoptotic signalling in senescent heart

(2014) Thomas K. Sin et al.   JOURNAL OF PHYSIOLOGY-LONDON

Nicotinamide Mononucleotide, an Intermediate of NAD+ Synthesis, Protects the Heart from Ischemia and Reperfusion

(2014) Takanobu Yamamoto et al.   PLoS One

Complement Component 3 is Necessary to Preserve Myocardium and Myocardial Function in Chronic Myocardial Infarction

(2014) Marcin Wysoczynski et al.   STEM CELLS

Activation of transient receptor potential vanilloid 1 decreases endothelial nitric oxide synthase phosphorylation at Thr497 by protein phosphatase 2B-dependent dephosphorylation of protein kinase C

(2013) L.-C. Ching et al.   Acta Physiologica

Calorie restriction and sirtuins revisited

(2013) L. Guarente   GENES & DEVELOPMENT

Calorie Restriction Attenuates Cardiac Remodeling and Diastolic Dysfunction in a Rat Model of Metabolic Syndrome

(2013) Miwa Takatsu et al.   HYPERTENSION

Effects of Caloric Restriction on Cardiac Oxidative Stress and Mitochondrial Bioenergetics: Potential Role of Cardiac Sirtuins

(2013) Ken Shinmura   Oxidative Medicine and Cellular Longevity

The effect of C1 inhibitor on myocardial ischemia and reperfusion injury

(2012) Fengxin Lu et al.   CARDIOVASCULAR PATHOLOGY

The Intersection Between Aging and Cardiovascular Disease

(2012) Brian J. North et al.   CIRCULATION RESEARCH

The complement system in ischemia–reperfusion injuries

(2012) William B. Gorsuch et al.   IMMUNOBIOLOGY

The many faces of insulin-like peptide signalling in the brain

(2012) Ana M. Fernandez et al.   NATURE REVIEWS NEUROSCIENCE

Role of complement and perspectives for intervention in ischemia-reperfusion damage

(2011) Yara Banz et al.   ANNALS OF MEDICINE

Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53

(2011) C. Zhang et al.   CARDIOVASCULAR RESEARCH

Caloric Restriction Primes Mitochondria for Ischemic Stress by Deacetylating Specific Mitochondrial Proteins of the Electron Transport Chain

(2011) Ken Shinmura et al.   CIRCULATION RESEARCH

SirT1 Regulates Adipose Tissue Inflammation

(2011) M. P. Gillum et al.   DIABETES

Cardiovascular protection afforded by caloric restriction: Essential role of nitric oxide synthase

(2011) Ken Shinmura   Geriatrics & Gerontology International

Sirtuins at a glance

(2011) T. Nakagawa et al.   JOURNAL OF CELL SCIENCE

Silent Information Regulator 1 Protects the Heart From Ischemia/Reperfusion

(2010) Chiao-Po Hsu et al.   CIRCULATION

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

(2010) Nirmala Hariharan et al.   CIRCULATION RESEARCH

Induction of Manganese Superoxide Dismutase by Nuclear Translocation and Activation of SIRT1 Promotes Cell Survival in Chronic Heart Failure

(2010) Masaya Tanno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impact of long-term caloric restriction on cardiac senescence: Caloric restriction ameliorates cardiac diastolic dysfunction associated with aging

(2010) Ken Shinmura et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

SIRT1 Deficiency Downregulates PTEN/JNK/FOXO1 Pathway to Block Reactive Oxygen Species-Induced Apoptosis in Mouse Embryonic Stem Cells

(2010) Hee-Don Chae et al.   STEM CELLS AND DEVELOPMENT

A Role for Complement in the Enhanced Susceptibility of Steatotic Livers to Ischemia and Reperfusion Injury

(2009) S. He et al.   JOURNAL OF IMMUNOLOGY

Impact of 6-mo caloric restriction on myocardial ischemic tolerance: possible involvement of nitric oxide-dependent increase in nuclear Sirt1

(2008) Ken Shinmura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mechanisms Underlying Caloric Restriction and Lifespan Regulation

(2008) Zoltan Ungvari et al.   CIRCULATION RESEARCH

SirT1 Regulates Energy Metabolism and Response to Caloric Restriction in Mice

(2008) Gino Boily et al.   PLoS One