期刊
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
卷 310, 期 1, 页码 E1-E14出版社
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/ajpendo.00429.2015
关键词
HDL; obesity; type 2 diabetes mellitus; inflammation; bone; brain; obstructive pulmonary; disease
资金
- European Social Fund (ESF)
- Greek State [248]
- Hellenic State Scholarships Foundation (IKY)
- action Excellence of the Operational Program Education and Lifelong Learning (Action's Beneficiary: Hellenic General Secretariat for Research and Technology)
Emerging evidence strongly supports that changes in the HDL metabolic pathway, which result in changes in HDL proteome and function, appear to have a causative impact on a number of metabolic disorders. Here, we provide a critical review of the most recent and novel findings correlating HDL properties and functionality with various pathophysiological processes and disease states, such as obesity, type 2 diabetes mellitus, nonalcoholic fatty liver disease, inflammation and sepsis, bone and obstructive pulmonary diseases, and brain disorders.
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