Article
Engineering, Biomedical
Sahar Abbasi, Gholamhossein Yousefi, Ali-mohammad Tamaddon, Omidreza Firuzi
Summary: The study aimed to investigate the in vitro properties of Paclitaxel-loaded nanomicelles on multidrug resistance cell lines, revealing higher cytotoxicity and induction of apoptosis in the resistant cells. The copolymer was found to inhibit P-gp efflux pumps and could be a promising system against multidrug resistance tumors in vivo.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2021)
Review
Chemistry, Multidisciplinary
Yoo Kyung Go, Cecilia Leal
Summary: The article discusses the significance of hierarchic self-assembly in synthetic or biological soft materials, focusing on the form and function of lipid and polymer hybrid systems and their applications in controlled drug delivery.
Article
Chemistry, Multidisciplinary
Wenhao Pan, Lei Zhang, Lei Li, Jie Cen, Rundi Song, Chengzhou Song, Guoying Zhang, Jinming Hu, Shiyong Liu
Summary: This study reports the synthesis of well-defined polypeptides containing semicarbazide moieties via direct polymerization of N-phenoxycarbonyl-functionalized alpha-amino acid (NPCA) based monomers. These polypeptides can be further decorated with ketone/aldehyde-containing agents with the formation of pH-cleavable semicarbazone linkages. The intracellular acidic pH-triggered release promotes drug escape from endolysosomes and enhances anti-tumor efficacy, which can be also employed for highly sensitive detection of tumor lesions.
ADVANCED MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Wenfeng Gou, Na Luo, Bing Yu, Hongying Wu, Shaohua Wu, Chen Tian, Jianghong Guo, Hongxin Ning, Changfen Bi, Huiqiang Wei, Wenbin Hou, Yiliang Li
Summary: UA232, a derivative of ursolic acid, demonstrates anti-tumor effects against breast and cervical cancer cells by inducing apoptosis and promoting autophagy. The compound exerts its pharmacological effects through triggering endoplasmic reticulum stress and lysosomal dysfunction, making it a promising candidate for cancer treatment.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
(2022)
Review
Biochemistry & Molecular Biology
Wojciech Trybus, Ewa Trybus, Teodora Krol
Summary: Lysosomes are organelles that contain acidic hydrolases and play a crucial role in cellular degradation and homeostasis. They are involved in autophagy and various cell death pathways, including lysosomal and apoptotic death. Compounds such as lysosomotropic compounds, antihistamines, DNA-damaging drugs, and chemotherapeutics can induce lysosomal membrane permeability, promoting lysosomal-mediated cell death. Combining lysosomotropic compounds with autophagy modulators may be a promising approach in cancer treatment and overcoming chemoresistance.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Marcus Y. Chin, Anand R. Patwardhan, Kean-Hooi Ang, Austin L. Wang, Carolina Alquezar, Mackenzie Welch, Phi T Nguyen, Michael Grabe, Anna Molofsky, Michelle R. Arkin, Aimee W. Kao
Summary: A novel genetically encoded fluorescent protein-based pH biosensor called FIRE-pHLy was designed to better understand lysosomal pH, enabling ratiometric quantification and targeting lysosomes with LAMP1. The biosensor reported lumenal pH between 3.5 and 6.0 with mTFP1 and enabled quantification of the alkalinizing response to bafilomycin Al in various cellular models. FIRE-pHLy is a specific, robust, and versatile lysosomal pH biosensor with broad applications in investigating pH dynamics in aging- and lysosome-related diseases and lysosome-based drug discovery.
Article
Engineering, Biomedical
Jie Zhang, Liwen Wei, Xiaocao Ma, Jingguo Wang, Siping Liang, Kang Chen, Minhao Wu, Li Niu, Yuanqing Zhang
Summary: A versatile biomimetic nanoplatform, HM-BPT, was developed to target the tumor microenvironment (TME) and deliver a glutamine metabolism inhibitor, BPTES. HM-BPT treatment showed significant tumor inhibition, infiltration of cytotoxic T lymphocytes (CTL), and activation of the STING pathway in macrophages. Furthermore, the combination of glutathione depletion and oxygen supply improved the immunosuppressive status of the TME and enhanced antitumor immune responses.
ACTA BIOMATERIALIA
(2023)
Article
Polymer Science
Meirong Zhao, Weiwei Jiang, Xinrong Xie, Yogini Jaiswal, Leonard Williams, Mei Wei, Ying Mo, Yifu Guan, Hua Yang
Summary: In this paper, a new drug carrier was synthesized using self-assembled polymeric micelles to load paclitaxel. The drug-loading content of the carrier prepared by the optimized method was 1.97%. The results indicate that the developed carrier has good pH sensitivity and potential for increased solubility and clinical efficacy of paclitaxel.
Article
Chemistry, Multidisciplinary
Eunbin Hwang, Hyo Sung Jung
Summary: The article discusses the advancements in organelle-targeted photothermal therapy (PTT) agents for anticancer treatment and provides a structured approach for describing the types and properties of these agents. Representative agents used in the field since 2010 are summarized, along with the latest advances in improving therapeutic efficacy across different types of cancers.
CHEMICAL COMMUNICATIONS
(2021)
Article
Biophysics
Qiang Li, Dongsheng Fu, Jie Zhang, Hong Yan, Huifang Wang, Baolong Niu, Ruijie Guo, Yiming Liu
Summary: A new type of polypeptide-based dual-sensitive drug delivery system was synthesized for efficient chemotherapy. The nanoparticles showed enhanced drug release in acidic and hypoxic environments, leading to higher cytotoxicity against lung cancer cells. This system has the potential to be a promising platform for stimuli-responsive controlled drug release in cancer therapy.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Biochemistry & Molecular Biology
Yang Han, Jieyi Pan, Na Liang, Xianfeng Gong, Shaoping Sun
Summary: The study synthesized an amphiphilic conjugate based on mPEG and cholesterol-modified chitosan with hydrazone bonds, which was used to prepare PTX-loaded micelles. These micelles exhibited promising therapeutic efficacy of PTX and reduced side effects, indicating potential as pH-sensitive nanocarriers for drug delivery.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Multidisciplinary
Zhiwei Zhang, Jingjing Xiang, Lijiao Guan, Pu Chen, Changzhong Li, Chunlei Guo, Yan Hu, Saipeng Huang, Lintao Cai, Ping Gong
Summary: By designing and synthesizing a pH-activated photothermal sensitizer IR-PE, it is possible to trigger the lysosomal dysfunction-mediated Fenton pathway under near-infrared light irradiation, thereby inducing ferroptosis and improving antitumor efficacy while mitigating systemic side effects.
Article
Multidisciplinary Sciences
Yayu Wang, Wenping Zeng, Bingqian Lin, Yichuan Yao, Canjun Li, Wenqi Hu, Haotian Wu, Jiamin Huang, Mei Zhang, Tian Xue, Dejian Ren, Lili Qu, Chunlei Cang
Summary: NCLs are a group of lysosomal storage diseases caused by autosomal recessive mutations. One variant of NCL, vLINCL, is caused by mutations in the lysosomal membrane protein CLN7, which has been identified as a novel endolysosomal chloride channel. Overexpression of CLN7 can increase chloride currents and enlarge endolysosomes, suggesting a potential treatment strategy for vLINCL.
Article
Chemistry, Physical
Haiqin Du, Sandra Kalem, Cecile Huin, Nicolas Illy, Guillaume Tresset, Fernando Carlos Giacomelli, Philippe Guegan
Summary: In this study, star amphiphilic copolymers with a beta-cyclodextrin (pCD) core and seven poly (butylene oxide)-block-polyglycidol (PBO-PGL) arms per side were synthesized and characterized for polymersome-based nanoreactor purposes. The self-assembly behavior and ion permeability of the membranes were investigated. The results showed that the morphology of the self-assemblies was determined by the hydrophobic-to-hydrophilic ratio, and the pCD-containing membranes exhibited lower permeability to H. and influenced the K.Cl- permeability.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
K. Laxmi Swetha, Milan Paul, Kavya Sree Maravajjala, Soniya Kumbham, Swati Biswas, Aniruddha Roy
Summary: Previous studies have shown that breast cancer cells employ various strategies to resist anticancer drugs, such as docetaxel, through drug-resistance mechanisms like overexpression of P-glycoprotein and cancer stem cells. By inhibiting both P-glycoprotein and cancer stem cells, the combination of docetaxel and disulfiram shows potential in sensitizing drug-resistant breast cancer cells. This study developed a pH-responsive nanoparticle system for the co-delivery of docetaxel and disulfiram, which demonstrated improved drug release, penetration, and cytotoxic efficacy against drug-resistant breast cancer cells in vitro, as well as enhanced tumor drug delivery and anti-tumor efficacy in vivo.
JOURNAL OF CONTROLLED RELEASE
(2023)
Article
Pharmacology & Pharmacy
Sanaz Jauanmardi, Ali Mohammad Tamaddon, Mahmoud Reza Aghamaali, Ladan Ghahramani, Samira Sadat Abolmaali
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2020)
Article
Food Science & Technology
Najme Oliyaei, Marzieh Moosavi-Nasab, Ali Mohammad Tamaddon, Mahboubeh Fazaeli
FOOD SCIENCE & NUTRITION
(2020)
Article
Materials Science, Multidisciplinary
Zahra Rahiminezhad, Ali Mohammad Tamaddon, Sedigheh Borandeh, Samira Sadat Abolmaali
APPLIED MATERIALS TODAY
(2020)
Article
Nanoscience & Nanotechnology
Mehdi Abedi, Samira Sadat Abolmaali, Mozhgan Abedanzadeh, Fatemeh Farjadian, Soliman Mohammadi Samani, Ali Mohammad Tamaddon
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2020)
Article
Biochemistry & Molecular Biology
Omolbanin Shahraki, Mehdi Khoshneviszadeh, Mojtaba Dehghani, Maryam Mohabbati, Marjan Tavakkoli, Luciano Saso, Najmeh Edraki, Omidreza Firuzi
Article
Pharmacology & Pharmacy
Mozhgan Abedanzadeh, Mohsen Salmanpour, Fatemeh Farjadian, Samaneh Mohammadi, Ali Mohammad Tamaddon
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2020)
Review
Medicine, General & Internal
Vahid Alimardani, Samira Sadat Abolmaali, Gholamhossein Yousefi, Zahra Rahiminezhad, Mehdi Abedi, Alimohammad Tamaddon, Samad Ahadian
Summary: Organic and inorganic nanoparticles have shown promising outcomes in transdermal drug delivery, but crossing the stratum corneum remains a challenge. Microneedle array technology has recently revealed promising outcomes in the delivery of various formulations, especially nanoparticles to deliver both hydrophilic and hydrophobic therapeutic agents.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Biotechnology & Applied Microbiology
Mahboobeh Jafari, Samira Sadat Abolmaali, Ali Mohammad Tamaddon, Kamiar Zomorodian, Bahador Shahriarirad (Sarkari)
Summary: Research has shown that nano-based systems can improve the therapeutic effects of Amphotericin B and reduce its toxicities, but commercial lipid formulations are limited in use due to their high cost.
Article
Pharmacology & Pharmacy
Sara Kheirkhah, Mehdi Abedi, Fateme Zare, Mohsen Salmanpour, Samira Sadat Abolmaali, Ali Mohammad Tamaddon
Summary: In this study, mesoporous silica nanoparticles (MSNs) were used as a delivery strategy for dexamethasone (DEX) to overcome its unfavorable pharmacokinetics and side effects. The MSNs were modified to improve drug loading and then combined with lipid bilayers to sustain drug release. The optimized MSNs showed high-capacity DEX loading, long-term release, and hemocompatibility, indicating their potential application in chronic inflammatory diseases.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Review
Pharmacology & Pharmacy
Zohre Montaseri, Samira Sadat Abolmaali, Ali Mohammad Tamaddon, Fakhrossadat Farvadi
Summary: Cartilage tissue engineering requires an appropriate microenvironment for chondrocyte proliferation. Composite silk fibroin hydrogels have shown strong potential and advantages for cartilage regeneration.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Mana Heidari, Mohsen Salmanpour, Haniyeh Najafi, Maryam Monajati, Zahra Rahiminezhad, Negar Azarpira, Samira Sadat Abolmaali, Ali Mohammad Tamaddon
Summary: Over-expression of miR21a is shown to drive cancer progression by promoting cancer cell proliferation, migration, invasion, and metastasis. In this study, a beta cyclodextrin-polyethyleneimine-graphene quantum dot (beta CD-PEI-GQD) nanocarrier was developed for efficient delivery of miR21a, leading to significant downregulation of miR21 expression levels.
Article
Multidisciplinary Sciences
Ali Mohammad Tamaddon, Rahman Bashiri, Haniyeh Najafi, Khadijeh Mousavi, Mahboobeh Jafari, Sedigheh Borandeh, Mahdokht H. Aghdaie, Mina Shafiee, Samira Sadat Abolmaali, Negar Azarpira
Summary: The cytotoxicity and genotoxicity of graphene oxide (GO) modified by different amino acids were evaluated. The results showed that the modified GO caused less cellular and genetic damage, with GO modified with aspartic acid exhibiting the lowest toxicity. This indicates the superior potential of modified GO in biomedical applications such as cell therapy and tissue engineering.
Article
Nanoscience & Nanotechnology
Zahra Janipour, Haniyeh Najafi, Samira Sadat Abolmaali, Reza Heidari, Negar Azarpira, Emine Dilek Ozyilmaz, Ali Mohammad Tamaddon
Summary: In this study, a peptide hydrogel containing SMV was designed and characterized. The results showed that the FmocFF-SMV hydrogel had fibrous structure and shear-thinning characteristics, leading to improved diabetic wound recovery and reduced inflammation.
ACS APPLIED BIO MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Mahboobeh Jafari, Samira Sadat Abolmaali, Sedigheh Borandeh, Haniyeh Najafi, Zahra Zareshahrabadi, Omid Koohi-Hosseinabadi, Negar Azarpira, Kamiar Zomorodian, Ali Mohammad Tamaddon
Summary: In this study, we successfully reduced the toxicity of amphotericin B (AMB) and improved its therapeutic efficacy by developing POSS-HPG@Chol/AMB nanostructures. These nanostructures provided complete protection against Candida infections in a mouse model and effectively reduced or eliminated AMB-induced liver and kidney injuries.
Article
Chemistry, Multidisciplinary
Mahboobeh Jafari, Samira Sadat Abolmaali, Sedigheh Borandeh, Haniyeh Najafi, Zahra Zareshahrabadi, Omid Koohi-Hosseinabadi, Negar Azarpira, Kamiar Zomorodian, Ali Mohammad Tamaddon
Summary: In this study, new polyhedral oligomeric silsesquioxane – hyperbranched polyglycerol dendrimers were developed to improve the safety and therapeutic efficacy of AMB. The synthesized dendrimers showed lower concentrations and toxicities against Candida spp. compared to conventional formulations, and they effectively protected mice from severe Candida infections and reduced organ injuries caused by AMB.
Article
Biophysics
Cristina Potrich, Anna Pedrotti, Cecilia Pederzolli, Lorenzo Lunelli
Summary: This study developed different functional surfaces for capturing exosomes and verified their effectiveness through experiments. Among them, the negatively-charged surface performed the best, capturing a large number of exosomes and successfully analyzing their biomarkers.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Brojendra Nath Saren, Srushti Mahajan, Mayur Aalhate, Rahul Kumar, Essha Chatterjee, Indrani Maji, Ujala Gupta, Santosh Kumar Guru, Pankaj Kumar Singh
Summary: This study developed P-selectin-targeted dasatinib nanoparticles coated with chitosan and fucoidan (DST-CH-FUC-NPs), which showed sustained release, reduced hemolytic potential, increased cytotoxicity and cellular uptake compared to free dasatinib. These nanoparticles also demonstrated enhanced ROS production, mitochondrial membrane potential damage, apoptosis induction, cell migration inhibition, and disruption of lysosomal membrane integrity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Weiping Deng, Xiaohui Li, Ya Li, Zhongbing Huang, Yulin Wang, Ning Mu, Juan Wang, Tunan Chen, Ximing Pu, Guangfu Yin, Hua Feng
Summary: This study demonstrates the importance of chirality in nerve repair by constructing a GO-phenylalanine derivative hydrogel system. In vivo experiments show that the dextro group significantly improves functional recovery and histological restoration in rat sciatic nerve repair models. The doped GO promotes angiogenesis and myelination. These results suggest that chirality plays a crucial role in promoting nerve regeneration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xiaoyan Wang, Jin Gao, Yu Gao, Linlin Zhang, Congchao Xu, Qintong Li, Lin Li, Jianliang Xue
Summary: In this study, a highly effective surfactant producer strain, Bacillus Cereus GX7, was isolated from the oil tank bottom sludge of Shengli Oil Field in China. The biosurfactant produced by GX7 was identified as surfactin, a lipopeptide surfactant, through TLC, FT-IR, and LC-MS/MS analysis. The fermentation process of GX7 was optimized using single-factor experiments, focusing on the composition of fermentation medium and fermentation conditions. Glucose and peptone were found to be the best carbon and nitrogen sources, and the optimum temperature, inoculum amount, pH, rotation speed, and fermentation time for the strain were determined to be 30°C, 1%, 7.5, 150 rpm, and 48 h, respectively. After optimization, the surface tension and emulsification index of the fermentation broth were 26.84 mN/m and 57.84%, respectively. Furthermore, the biosurfactant produced by GX7 demonstrated good stability over a wide range of temperature, pH, and salt concentration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Rodney Marcelo do Nascimento, Christine Grauby-Heywang, Houssem Kahli, Nesrine Debez, Laure Beven, Ivan Helmuth Bechtold, Touria Cohen Bouhacina
Summary: This article presents a theoretical model based on thermodynamic rules to assess the early stages of bacterial biofilm formation on different material surfaces. By utilizing morphological characteristics of bacteria and Atomic Force Microscopy images, the model generates a dataset of energetically minimized states, which can be correlated with bacterial adhesion states.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Filipa A. L. S. Silva, Licinia Timochenco, Raquel Costa-Almeida, Jose Ramiro Fernandes, Susana G. Santos, Fernao D. Magalhaes, Artur M. Pinto
Summary: The study demonstrates that by photoreducing nanosized graphene oxide using ultraviolet radiation, nanometric particles with high light-to-heat conversion efficiency and water stability can be obtained. These nanomaterials exhibit high absorption in the near-infrared region and show no cytotoxicity towards human cells, indicating their potential for safe therapy.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
D. Costa, V. De Matteis, F. Treso, G. Montani, M. Martino, R. Rinaldi, M. Corrado, M. Cascione
Summary: This review primarily discusses the relationship between contact lens discomfort (CLD) and the surface properties of contact lenses (CLs), specifically the coefficient of friction (CoF). The review emphasizes the importance of introducing a standardized protocol for measuring CoF and calls for a more precise evaluation of the relationship between surface properties and comfort in CLs users.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Debdip Brahma, Tamal Sarkar, Rupal Kaushik, Akshay Narayan Sarangi, Amar Nath Gupta
Summary: This in-vitro study evaluates the effect of reactive oxygen species (ROS) on the structural rearrangement of elastin. The results show that oxidative stress leads to a decrease in protein size and changes in secondary structure, potentially promoting protein aggregation. This study is important for therapeutics aiming to prevent elastin degradation and aging.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xin Yang, Qiang Wang, Chaoxi Yan, Degang Huang, Yinchang Zhang, Huazheng He, Shouliang Xiong, Congming Li, Pingbo Chen, Tingjun Ye, Dan Hu, Lei Wang
Summary: This study presents a practical and effective strategy to improve osseointegration in patients with osteoporosis. By coating titanium implants with polydopamine followed by strontium modification, the bi-functional implants promote bone regeneration and immune regulation. The results show good biocompatibility, sustained release of strontium ions, and stable osseointegration between bone tissues and implants.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Sengwang Fu, Jianping Zhu, Zhijun Jiang, Yue Cao, Yufei Chen, Lihao Zhang, Sunlong Li, Weipeng Lu, Chengbin Miao, Qing He, Qi Li, Weixing Zhang, Lehao Ren, Yachun Li, Hongchao Shi, Cihui Liu
Summary: Effective management of biofluids is crucial for in vivo surgical interventions. Recent advances include self-sealing needles, drug-eluting stents, and shear-thinning hydrogels. However, complications associated with intestinal mucosal injury and secondary damage still persist. In this study, researchers developed an interpenetrating Janus wettability stent coating that enables unidirectional draining of excessive biofluid. They also demonstrated directional biofluid movement using a self-pumping dressing with potential applications in biofluid collection and disease diagnosis through metal ion detection. This integrated system presents an opportunity for designing wound dressings with effective biofluid management and metal ion detection capabilities.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Maryam Hassani, Mojtaba Kamankesh, Mazda Rad-Malekshahi, Kobra Rostamizadeh, Farhad Rezaee, Ismaeil Haririan, Seyed Mojtaba Daghighi
Summary: Bacterial adhesion and biofilm formation on the surface of biomaterial implants is a critical problem, and a polymer brush coating with antiadhesive and antimicrobial properties has proven to be highly effective in resolving this issue.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Huaihong Zhang, Na Liu, Yuting Zhang, Hui Cang, Zhaosheng Cai, Ziqun Huang, Jun Li
Summary: A functionalized cationic polymer, CR-PQAC, was designed and synthesized for photothermal enhanced antimicrobial therapy. The CR-PQAC nanoparticles exhibited significant antibacterial activity and low cytotoxicity against mammalian cells.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Ipsita Sahu, Priyadarshi Chakraborty
Summary: Peptide nanotechnology bridges the gap between materials and biological worlds by utilizing self-assembly of short-peptide building blocks. Hydrogels engineered from these short peptides show great potential in biomedical applications, but their weak mechanical properties and limited functional diversity need to be addressed. Nanoengineering the networks of these hydrogels by incorporating small molecules, polymers, and inorganic/carbon nanomaterials can enhance their mechanical properties and expand their functional diversity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Hao Wei, Yajun Gu, Ao Li, Panpan Song, Dingding Liu, Feihu Sun, Xiaofeng Ma, Xiaoyun Qian
Summary: In this study, a stable three-dimensional conductive hydrogel was prepared by cross-linking MXenes to Matrigel hydrogel. The conductive hydrogel promotes the proliferation and differentiation of NSCs, providing new strategies for neural tissue engineering.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Yue Zhong, Xiaoli Ge, Juan Zhang, Qun Wei, Feng Wang, Yongke Zhong
Summary: The effect of oxygenic groups on the hemocompatibility of activated carbon was studied through liquid-phase oxidation and subsequent heat treatment. Results showed that the presence of oxygenic groups improved hemocompatibility, while their removal decreased it.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
