期刊
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY
卷 18, 期 4, 页码 1079-1093出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s10237-019-01129-1
关键词
Skin biomechanics; Mechanical characterization; Compressibility; Porous media; Osmotic pressure
资金
- Swiss National Science Foundation [179012]
A total of 37 human and 33 murine skin samples were subjected to uniaxial monotonic, cyclic, and relaxation experiments. Detailed analysis of the three-dimensional kinematic response showed that skin volume is significantly reduced as a consequence of a tensile elongation. This behavior is most pronounced in monotonic but persists in cyclic tests. The dehydration associated with volume loss depends on the osmolarity of the environment, so that tension relaxation changes as a consequence of modifying the ionic strength of the environmental bath. Similar to ex vivo observations, complementary in vivo stretching experiments on human volar forearms showed strong in-plane lateral contraction. A biphasic homogenized model is proposed which allows representing all relevant features of the observed mechanical response.
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