Article
Polymer Science
Qimin Jiang, Liang Zhao, Yongzhuang Du, Wenyan Huang, Xiaoqiang Xue, Hongjun Yang, Li Jiang, Qilin Jiang, Bibiao Jiang
Summary: This study describes the one-pot synthesis of novel thermoresponsive nonconjugated fluorescent branched poly(ether amide)s and characterizes their structure and properties through a series of analysis methods. The results show that these polymers have a lower critical solution temperature and exhibit LCST-dependent fluorescent behavior within a specific temperature range. Moreover, these polymers demonstrate good biocompatibility and bright cell imaging capabilities.
Article
Materials Science, Multidisciplinary
Xiao-lin Guan, Xue-qin Yang, Shou-jun Lai, Yuan-yuan Ding, Jing-yu Wei, Jia-ming Zhang, Li-yuan Zhang, Cheng-hao Li, Jin-hui Tong, Zi-qiang Lei
Summary: A series of deep-red/NIR non-conjugated polymers with aggregation-induced emission were designed and synthesized, exhibiting excellent biodegradability and biocompatibility for bioimaging applications.
MATERIALS & DESIGN
(2022)
Article
Polymer Science
Yuanhao Zhang, Yubo Zhou, Zhen Wang, Jingling Yan
Summary: Colorless polyimide films have great potential for flexible display applications due to their excellent optical transparency and thermal and mechanical properties. By adjusting the molar ratios of monomers, the thermal, mechanical, and optical properties of the copolymers were optimized. The incorporation of amide linkages significantly improved the mechanical properties and dimensional stability of the films. The adoption of CBDA suppressed the formation of charge transfer complexes, resulting in well-balanced optical properties.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Polymer Science
Xingfeng Lei, Guo Xiong, Yuyang Xiao, Tianhao Huang, Xiangze Xin, Shuyu Xue, Qiuyu Zhang
Summary: By incorporating amide hydrogen bonding interactions, researchers have developed a new material called poly(amide-imide) hybridization networks, which exhibit superior shape memory behavior, thermal stability, and mechanical strength, making them promising candidates for aerospace applications.
Article
Polymer Science
Taejoon Byun, Seong Jong Kim, Sang Youl Kim
Summary: Soluble aromatic poly(amide-imide)s with controlled imide/amide bond ratio were synthesized from a new diamide-diamine monomer. These materials exhibited high thermal stability and solubility, and could be used to fabricate flexible films.
Article
Chemistry, Multidisciplinary
A. Young Kim, Seon Ju Lee, Moon Young Choi, Changyub Na, Lee Ku Kwac, Hong Gun Kim, Jin-Hae Chang
Summary: Polyamic acid (PAA) was synthesized using specific monomers and transformed into colorless transparent poly(amide imide) (CPAI) hybrid films. The CPAI hybrid films were prepared by dispersing organoclay STN in CPAI, and the properties were studied based on the dispersed STN content. While some clay were agglomerated, most clays were well-dispersed in nano-size. The best thermomechanical properties were achieved with an STN content of 3 wt%.
Article
Chemistry, Multidisciplinary
Jaegun Lee, Ju-Young Choi, Junhwan Jang, Sechang Park, Gyumin Ji, Seung-Hyun Lee, Dam-Bi Kim, Kang-Hoon Yoon, Chan-Moon Chung, Soohaeng Cho
Summary: This study fabricated multilayer electrodes composed of GCA/AgNW/GCA/cPAI, which exhibited improved mechanical durability and applicability for nonvolatile memory.
Article
Polymer Science
Taejoon Byun, Seong Jong Kim, Sang Youl Kim
Summary: Transparent and soluble poly(amide-imide)s (PAIs) with high dimensional stability were successfully synthesized using specific monomer synthesis method, and the prepared PAIs exhibited excellent properties with simple fabrication process.
Article
Polymer Science
Ge Zhu, Haoji Lao, Feng Feng, Minyan Wang, Xingzhong Fang, Guofei Chen
Summary: Two series of poly(amide imide)s (PAIs) were synthesized via thermal imidization using novel isomeric amide-containing diamine monomers and different commercial aromatic dianhydrides. These PAIs exhibited excellent thermal and mechanical properties, making them potential candidates for flexible displays. The effects of the isomeric monomers on film properties were compared.
EUROPEAN POLYMER JOURNAL
(2022)
Article
Polymer Science
Ge Zhu, Haoji Lao, Feng Feng, Minyan Wang, Xingzhong Fang, Guofei Chen
Summary: Two series of poly(amide imide)s (PAIs) with excellent high temperature performance, low coefficient of thermal expansion, and high mechanical properties were synthesized via thermal imidization. These PAIs have potential applications in flexible displays. The effects of different amide-containing diamine monomers on film properties were investigated.
EUROPEAN POLYMER JOURNAL
(2022)
Article
Polymer Science
Ran Yu, Chao Xu, Xiaopei Wu, Honglian Dai
Summary: We investigated the properties of polyoxyethylene diamine (H2N-PEG-NH2) and poly(amide-imide)-polyethylene glycol (PAI-PEG) copolymers and found that the material had the best elongation at break and recovery when the PEG content was 5%. The degradation rate, hydrophilic property, tensile strength, and tensile modulus of the copolymer decreased with increasing PEG content. The material showed the best thermal stability and mechanical properties when 5% PEG was added. Cytocompatibility evaluation demonstrated that the addition of PEG enhanced the cell compatibility of the material, making it potentially suitable for bone repair applications.
Article
Materials Science, Composites
Zhenyu Ma, Yinchuan Pu, Yudong Huang, Li Liu, Yuan Yao
Summary: The study synthesized poly(amide-imide) (PAI) with reactive catechol pendant groups as the sizing for carbon fiber, improving the mechanical properties of CF/PEI and CF/PEEK composites. The improved interface in composites contributed to the increased performance by bridging PAI between CF surface and PEI, PEEK matrices.
COMPOSITES SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Deyu Niu, Tianfeng Shen, Pengwu Xu, Manman Yu, Tianxi Liu, Weijun Yang, Zhenyu Wang, Piming Ma
Summary: In this study, a new organic compound HBNA was used as nucleator to prepare PLA/HBNA blends with enhanced crystallization, heat resistance, and transparency. The addition of 0.75 wt% HBNA increased the crystallization temperature of PLA from 90℃ to 123℃, and reduced the half-crystallization time from 31.0 min to 1.5 min at 135℃. The PLA/HBNA blends also maintained good transparency and heat resistance. This research is expected to broaden the application of PLA in packaging and other fields.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Materials Science, Composites
Zhenyu Ma, Yinchuan Pu, Yudong Huang, Li Liu, Chengce Yuan
Summary: In this study, a novel quaternized poly (amide-imide) (PAI) sizing with excellent solubility and thermal stability was synthesized. The aqueous thermoplastic carbon fiber (CF) sizing without surfactants was prepared using self-emulsifying of quaternized PAI, which remained stable after 12 months of storage. PAI-sized CF with suitable processability was obtained for the manufacture of CF/polyether-imide (PEI) and CF/polyether-ether-ketone (PEEK) composites. The mechanical properties and hydrothermal aging resistance of the composites were significantly improved. Quantum chemical calculations were used to explore the mechanisms of interface strengthening in the composites, which involved hydrogen bonding and pi-pi stacking between the PAI sizing and PEI, PEEK matrix.
COMPOSITES COMMUNICATIONS
(2022)
Article
Chemistry, Applied
Manzar Zahra, Sonia Zulfiqar, Muhammad Farooq Wahab, Muhammad Ilyas Sarwar
Summary: A new family of poly(amide-imide)s (PAIs) was synthesized and investigated as potential cationic sorbents for water treatment. The PAIs were characterized using spectroscopic analysis and exhibited high thermal stability. PAI-2 showed the highest adsorption capacity for Cd(II) and Pb(II) ions.
REACTIVE & FUNCTIONAL POLYMERS
(2022)
Article
Gastroenterology & Hepatology
Xueyan Chen, Yu Liu, Donghui Pan, Maoyu Cao, Xinyu Wang, Lizhen Wang, Yuping Xu, Yan Wang, Junjie Yan, Juan Liu, Min Yang
Summary: A PET imaging method for noninvasive GE measurement was established, demonstrating the efficacy of MCD on delayed GE. The study synthesized [Ga-68]Ga-NOTA as a tracer, used sesame paste as test meals, and successfully quantified GE using PET imaging. Additionally, constipation mice treated with MCD showed improvement in body weight and fecal conditions.
BMC GASTROENTEROLOGY
(2021)
Article
Engineering, Environmental
Jianjun Xiong, Junjie Yan, Cong Li, Xinyu Wang, Lizhen Wang, Donghui Pan, Yuping Xu, Fang Wang, Xinxin Li, Qiong Wu, Jingjing Liu, Yuhang Liu, Qingfeng Liu, Yixiang Zhou, Min Yang
Summary: A local injectable LM-doxorubicin nanoflake-imbedded hydrogel with pH-triggered drug release was developed to enhance therapeutic efficacy for postoperative tumor relapse prevention. LM nanoflakes showed higher DOX loading capacity compared to LM-based nanospheres or nanorods, and further encapsulation within Pluronic F-127 was used to achieve long-term antitumor effect and minimize systemic toxicity. The nano-formulation was injected into the tumor resection cavity for local chemotherapy, showing enhanced therapeutic efficacy and biosafety compared to free drugs.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Urban Studies
Terence Y. M. Lam, Junjie Yan
Summary: This study found that the main supply barriers for CCRC development in Shanghai are operation management experience, financial risks, and government support policy. On the other hand, the main demand barriers are poor quality of services and living environment, rather than traditional family-oriented culture and affordability. Therefore, successful CCRC investment strategy should focus on partnering with experienced professional eldercare management companies and providing high-quality medical professionals and trained care personnel, along with intensive capital flows for land, construction, and operating costs.
INTERNATIONAL JOURNAL OF HOUSING MARKETS AND ANALYSIS
(2022)
Article
Engineering, Environmental
Junjie Yan, Xinyu Wang, Jianjun Xiong, Lizhen Wang, Donghui Pan, Yuping Xu, Min Yang
Summary: By constructing a library of aliphatic polyamides using thiolactone chemistry, the structure-NTILs relationship of aliphatic fluorescent polyamides was revealed. Aliphatic polyamides exhibit dual Polymerization-induced emissions (PIEs) and introducing a piperazine unit enables lysosome-specific anchoring for the resultant fluorescent polyamide.
CHEMICAL ENGINEERING JOURNAL
(2022)
Review
Engineering, Environmental
Xinyu Wang, Yeli Fan, Junjie Yan, Min Yang
Summary: Polyphenols, compounds found in natural plants, have various beneficial effects such as anti-tumor, anti-inflammatory, and antibacterial capacities. Polyphenol-based polymeric nanoparticles have emerged as promising drug carriers in biomedical engineering.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Donghui Pan, Yan Wang, Nan Xu, Yuping Xu, Xinyu Wang, Lizhen Wang, Junjie Yan, Lei Yu, Liyan Miao, Guangji Wang, Min Yang
Summary: In this study, a novel reporter system for PET imaging the behaviors of CAR T cells was constructed and evaluated. The system was able to effectively monitor the proliferation profiles of CAR T cells in solid tumor models. The pharmacodynamics and pharmacokinetics of CAR T cells in whole-body hematologic neoplasms were also evaluated using bioluminescence imaging and PET imaging.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2022)
Article
Oceanography
Xingchuan Liu, Fangguo Zhai, Junjie Yan, Yanzhen Gu, Yucheng Wang, Peiliang Li, Kejian Wu
Summary: The study found that typhoons can cause significant changes in three-dimensional circulation in the Yellow Sea, resulting in temperature changes below the surface layer and the fast southward movement of the Yellow Sea Cold Water Mass. The Yellow Sea is one of the most important large marine ecosystems in the world, and this study enriches our understanding of its response to typhoons.
JOURNAL OF GEOPHYSICAL RESEARCH-OCEANS
(2022)
Article
Psychology, Multidisciplinary
Junjie Yan, Jingwen Zeng, Peiduo Liu
Summary: The study conducted three experiments to investigate the effects of phasic alertness on representational momentum, finding that it enhances forward displacement and sensitivity regardless of motion speed. The results suggest that phasic alertness may influence representational momentum by modulating the process of executive control in the retention interval.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Biochemical Research Methods
Xinlin Zhong, Junjie Yan, Xiang Ding, Chen Su, Yuping Xu, Min Yang
Summary: Bioorthogonal click reactions have been extensively studied in various research fields due to their high reaction rate and reliable selectivity. Previous reviews mainly focused on 18F-labeling protocols for radiotracers and radiopharmaceuticals, but other radionuclides such as gallium-68, iodine-125, and technetium-99m are also used. This review provides a comprehensive summary of recent advances in radiotracers prepared using bioorthogonal click reactions, including small molecules, peptides, proteins, antibodies, nucleic acids, and nanoparticles based on different radionuclides. The combination of pretargeting with imaging modalities or nanoparticles, as well as clinical translation studies, is also discussed to showcase the potential of bioorthogonal click chemistry for radiopharmaceuticals.
BIOCONJUGATE CHEMISTRY
(2023)
Article
Engineering, Environmental
Junjie Yan, Chen Su, Kequan Lou, Min Gu, Xinyu Wang, Donghui Pan, Lizhen Wang, Yuping Xu, Chongyang Chen, Yu Chen, Daozhen Chen, Min Yang
Summary: With endogenous redox systems and multiple enzymes, living cells can store and utilize external energy through photo/ultrasonic synthesis/catalysis. In artificial systems, however, sonochemical energy is rapidly dissipated due to electron-hole pairs recombination and ROS termination. In this study, a nanohybrid (LMND@ZIF-90) is synthesized by integrating zeolitic imidazolate framework-90 (ZIF-90) and liquid metal (LM), which efficiently captures sonogenerated holes and electrons, suppressing electron-hole pairs recombination and storing ultrasonic energy for over ten days. The nanohybrid also exhibits acid-responsive release and faster dye degradation rate.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Review
Environmental Sciences
Yeli Fan, Donghui Pan, Min Yang, Xinyu Wang
Summary: Emerging pollutants (EPs) have become a global concern due to their serious threats to human and animal health. The radiolabelling and in vivo radionuclide imaging tracking of various EPs have provided valuable insights into their behavior and potential toxicity in organs and tissues.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Review
Medicine, Research & Experimental
Chongyang Chen, Jing Wang, Donghui Pan, Xinyu Wang, Yuping Xu, Junjie Yan, Lizhen Wang, Xifei Yang, Min Yang, Gong-Ping Liu
Summary: Multi-omics refers to the application of multiple high-throughput screening technologies in the study of human diseases, such as genomics, transcriptomics, single-cell transcriptomics, proteomics, and metabolomics. This review provides a comprehensive introduction to the various technical categories, experimental design considerations, integrated analysis methods, machine learning and deep learning approaches, and application in medical research and precision medicine. It also discusses the challenges, future directions, and emerging fields of single-cell multi-omics and spatial multi-omics. This review is important for researchers entering the field of multi-omics medical research.
Article
Materials Science, Biomaterials
Yeli Fan, Xinyu Wang, Ge Yan, Hongfang Gao, Min Yang
Summary: Inflammatory bowel diseases (IBDs) are chronic gastrointestinal inflammation, and the pro-inflammatory cytokine TNF-α plays a key role in its pathogenesis. We developed polyphenol-poloxamer nanoparticles loaded with anti-inflammatory INF as a novel IBD therapy, which can be administered rectally for localized drug delivery, prolonging drug activity and minimizing systemic exposure, showing high therapeutic potential.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Optics
Chen Peng, Qi Chao, Liu Renwei, Wang Zhenzhen, Luo Han, Yan Junjie, Liu Jiping, Deguchi Yoshihiro
Summary: Laser induced breakdown spectroscopy (LIBS) is used to analyze fly ash samples, and support vector machine regression (SVR) model is used to predict the carbon content. The study shows that the SVR model with radial basis function (RBF) kernel function achieves good accuracy and avoids underfitting. The SVR model based on the internal standard element characteristic spectrum has similar accuracy to the internal standard method, while the model based on the full spectrum shows overfitting. The SVR model based on the main element characteristic spectrum has high regression coefficient and low root mean square error, effectively avoiding underfitting and overfitting.
ACTA OPTICA SINICA
(2022)
