TO901317 inhibits the development of Hepatocellular Carcinoma by LXRα/Glut1 decreasing the glycometabolism

Impaired adipose expansion caused by liver X receptor activation is associated with insulin resistance in mice fed a high-fat diet

(2017) Yueting Dong et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Amelioration of amyloid β-induced retinal inflammatory responses by a LXR agonist TO901317 is associated with inhibition of the NF-κB signaling and NLRP3 inflammasome

(2017) Chunyan Lei et al.   NEUROSCIENCE

Role of glucose metabolism related gene GLUT1 in the occurrence and prognosis of colorectal cancer

(2017) Wenming Feng et al.   Oncotarget

Epidemiology of Hepatocellular Carcinoma in the Asia-Pacific Region

(2016) Ran Xu Zhu et al.   Gut and Liver

PTEN dephosphorylates AKT to prevent the expression of GLUT1 on plasmamembrane and to limit glucose consumption in cancer cells

(2016) Suratchanee Phadngam et al.   Oncotarget

Cold Exposure Improves the Anti-diabetic Effect of T0901317 in Streptozotocin-Induced Diabetic Mice

(2015) Mingming Gao et al.   AAPS Journal

Activation of the Liver X Receptor by Agonist TO901317 Improves Hepatic Insulin Resistance via Suppressing Reactive Oxygen Species and JNK Pathway

(2015) Ying Dong et al.   PLoS One

Activation of liver X receptors inhibits cadmium-induced apoptosis of human renal proximal tubular cells

(2015) Somsak Fongsupa et al.   TOXICOLOGY LETTERS

Liver X receptor activation induces apoptosis of melanoma cell through caspase pathway

(2014) Wenjun Zhang et al.   Cancer Cell International

Glucose transporter 1-mediated glucose uptake is limiting for B-cell acute lymphoblastic leukemia anabolic metabolism and resistance to apoptosis

(2014) T Liu et al.   Cell Death & Disease

Altered energy metabolism in cancer

(2013) Yi Zhang et al.   CANCER BIOLOGY & THERAPY

Epidemiology of Hepatocellular Carcinoma

(2013) Sahil Mittal et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

T0901317, a potent LXR agonist, is an inverse agonist of CAR

(2013) Yuichiro Kanno et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Concurrent Activation of Liver X Receptor and Peroxisome Proliferator-Activated Receptor Alpha Exacerbates Hepatic Steatosis in High Fat Diet-Induced Obese Mice

(2013) Mingming Gao et al.   PLoS One

Association of liver X receptors (LXRs) genetic variants to gallbladder cancer susceptibility

(2013) Kiran Lata Sharma et al.   TUMOR BIOLOGY

T090137 Inhibits Cisplatin-Induced Apoptosis in Ovarian Cancer Cells

(2011) Daniel H. Miller et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Lycopene and the LXRα agonist T0901317 synergistically inhibit the proliferation of androgen-independent prostate cancer cells via the PPARγ-LXRα-ABCA1 pathway

(2011) Chih-Min Yang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Modulation of Glucose Transporter 1 (GLUT1) Expression Levels Alters Mouse Mammary Tumor Cell Growth In Vitro and In Vivo

(2011) Christian D. Young et al.   PLoS One

Extracellular Matrix Degradation and Remodeling in Development and Disease

(2011) P. Lu et al.   Cold Spring Harbor Perspectives in Biology

Liver X receptors as regulators of macrophage inflammatory and metabolic pathways

(2010) Noelia A-González et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Liver X Receptor activation downregulates AKT survival signaling in lipid rafts and induces apoptosis of prostate cancer cells

(2010) A J C Pommier et al.   ONCOGENE

GLUT1 gene is a potential hypoxic marker in colorectal cancer patients

(2009) Fu-Yen Chung et al.   BMC CANCER

Liver X Receptors (LXR) as Therapeutic Targets in Dyslipidemia

(2008) Jerzy Bełtowski   Cardiovascular Therapeutics