Overcoming Hypoxia by Multistage Nanoparticle Delivery System to Inhibit Mitochondrial Respiration for Photodynamic Therapy

Bioinspired Hybrid Protein Oxygen Nanocarrier Amplified Photodynamic Therapy for Eliciting Anti-tumor Immunity and Abscopal Effect

(2018) Zhikuan Chen et al.   ACS Nano

CDK2 positively regulates aerobic glycolysis by suppressing SIRT5 in gastric cancer

(2018) Zhenyong Tang et al.   CANCER SCIENCE

Oxidative Phosphorylation as an Emerging Target in Cancer Therapy

(2018) Thomas M. Ashton et al.   CLINICAL CANCER RESEARCH

Synchronous delivery of oxygen and photosensitizer for alleviation of hypoxia tumor microenvironment and dramatically enhanced photodynamic therapy

(2018) Xiaomeng Guo et al.   DRUG DELIVERY

Selective delivery of PLXDC1 small interfering RNA to endothelial cells for anti-angiogenesis tumor therapy using CD44-targeted chitosan nanoparticles for epithelial ovarian cancer

(2018) Ga Hee Kim et al.   DRUG DELIVERY

Methylphenidate ameliorates hypoxia-induced mitochondrial damage in human neuroblastoma SH-SY5Y cells through inhibition of oxidative stress

(2018) Mei Zhu et al.   LIFE SCIENCES

An inhibitor of oxidative phosphorylation exploits cancer vulnerability

(2018) Jennifer R. Molina et al.   NATURE MEDICINE

Co-treatment of TGF-β3 and BMP7 is superior in stimulating chondrocyte redifferentiation in both hypoxia and normoxia compared to single treatments

(2018) Xiaobin Huang et al.   Scientific Reports

Uncoupling Hepatic Oxidative Phosphorylation Reduces Tumor Growth in Two Murine Models of Colon Cancer

(2018) Yongliang Wang et al.   Cell Reports

A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds

(2018) Balaraman Kalyanaraman et al.   Redox Biology

Tumor Oxygenation and Hypoxia Inducible Factor-1 Functional Inhibition via a Reactive Oxygen Species Responsive Nanoplatform for Enhancing Radiation Therapy and Abscopal Effects

(2018) Lingtong Meng et al.   ACS Nano

Top-down fabrication of shape-controlled, monodisperse nanoparticles for biomedical applications

(2018) Xinxin Fu et al.   ADVANCED DRUG DELIVERY REVIEWS

Papaverine and its derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism

(2018) Martin Benej et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomechanical interplay between anisotropic re-organization of cells and the surrounding matrix underlies transition to invasive cancer spread

(2018) Deok-Ho Kim et al.   Scientific Reports

MMP-2-responsive fluorescent nanoprobes for enhanced selectivity of tumor cell uptake and imaging

(2018) Lu Sun et al.   Biomaterials Science

Exploiting the cancer niche: Tumor-associated macrophages and hypoxia as promising synergistic targets for nano-based therapy

(2017) Vera L. Silva et al.   JOURNAL OF CONTROLLED RELEASE

SIRT3 mediates decrease of oxidative damage and prevention of ageing in porcine fetal fibroblasts

(2017) Xiaoxian Xie et al.   LIFE SCIENCES

Hypoxia-induced tumor cell resistance is overcome by synergistic GAPDH-siRNA and chemotherapy co-delivered by long-circulating and cationic-interior liposomes

(2017) Jibin Guan et al.   Nanoscale

The effect of ALA-PDT under normoxia and cobalt chloride (CoCl 2 )-induced hypoxia on adhesion molecules (ICAM-1, VCAM-1) secretion by colorectal cancer cells

(2017) Aleksandra Kawczyk-Krupka et al.   Photodiagnosis and Photodynamic Therapy

On thein vivophotochemical rate parameters for PDT reactive oxygen species modeling

(2017) Michele M Kim et al.   PHYSICS IN MEDICINE AND BIOLOGY

Aclarubicin, an anthracycline anti-cancer drug, fluorescently contrasts mitochondria and reduces the oxygen consumption rate in living human cells

(2017) Haruka Iihoshi et al.   TOXICOLOGY LETTERS

Manipulating tumor hypoxia toward enhanced photodynamic therapy (PDT)

(2017) Juanjuan Dang et al.   Biomaterials Science

Adenosine triphosphate is a critical determinant for VEGFR signal during hypoxia

(2016) Abdullah Al Mamun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

ACRIN 6684: Assessment of Tumor Hypoxia in Newly Diagnosed Glioblastoma Using 18F-FMISO PET and MRI

(2016) E. R. Gerstner et al.   CLINICAL CANCER RESEARCH

Licochalcone A induces T24 bladder cancer cell apoptosis by increasing intracellular calcium levels

(2016) XINHUI YANG et al.   Molecular Medicine Reports

Ultrasound Triggered Tumor Oxygenation with Oxygen-Shuttle Nanoperfluorocarbon to Overcome Hypoxia-Associated Resistance in Cancer Therapies

(2016) Xuejiao Song et al.   NANO LETTERS

Liposomes co-loaded with metformin and chlorin e6 modulate tumor hypoxia during enhanced photodynamic therapy

(2016) Xuejiao Song et al.   Nano Research

On-demand drug release of ICG-liposomal wedelolactone combined photothermal therapy for tumor

(2016) Xuwu Zhang et al.   Nanomedicine-Nanotechnology Biology and Medicine

The anti-malarial atovaquone increases radiosensitivity by alleviating tumour hypoxia

(2016) Thomas M. Ashton et al.   Nature Communications

Monitoring Tumor Hypoxia Using 18F-FMISO PET and Pharmacokinetics Modeling after Photodynamic Therapy

(2016) Xiao Tong et al.   Scientific Reports

Amplified Singlet Oxygen Generation in Semiconductor Polymer Dots for Photodynamic Cancer Therapy

(2015) Shouying Li et al.   ACS Applied Materials & Interfaces

Remotely Controlled Red Blood Cell Carriers for Cancer Targeting and Near-Infrared Light-Triggered Drug Release in Combined Photothermal-Chemotherapy

(2015) Xiaoqi Sun et al.   ADVANCED FUNCTIONAL MATERIALS

Design of Hybrid MnO2-Polymer-Lipid Nanoparticles with Tunable Oxygen Generation Rates and Tumor Accumulation for Cancer Treatment

(2015) Claudia R. Gordijo et al.   ADVANCED FUNCTIONAL MATERIALS

Exfoliative cytology as a tool for monitoring pre-malignant and malignant lesions based on combined stains and morphometry techniques

(2014) Ignacio Gonzalez Segura et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Rapid Analysis of Glycolytic and Oxidative Substrate Flux of Cancer Cells in a Microplate

(2014) Lisa S. Pike Winer et al.   PLoS One

Hypoxia-Induced Reactive Oxygen Species Cause Chromosomal Abnormalities in Endothelial Cells in the Tumor Microenvironment

(2013) Miyako Kondoh et al.   PLoS One

Stimulated release of photosensitizers from graft and diblock micelles for photodynamic therapy

(2011) Hsieh-Chih Tsai et al.   BIOMATERIALS

Arsenic Trioxide Treatment Decreases the Oxygen Consumption Rate of Tumor Cells and Radiosensitizes Solid Tumors

(2011) C. Diepart et al.   CANCER RESEARCH

Multistage nanoparticle delivery system for deep penetration into tumor tissue

(2011) C. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA