Mathematical modeling of erythrocyte chimerism informs genetic intervention strategies for sickle cell disease

Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells

(2015) M. D. Hoban et al.   BLOOD

Comparison of mathematical frameworks for modeling erythropoiesis in the context of malaria infection

(2015) Luis L. Fonseca et al.   MATHEMATICAL BIOSCIENCES

BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

(2015) Matthew C. Canver et al.   NATURE

β-globin gene transfer to human bone marrow for sickle cell disease

(2013) Zulema Romero et al.   JOURNAL OF CLINICAL INVESTIGATION

A semi-mechanistic red blood cell survival model provides some insight into red blood cell destruction mechanisms

(2013) Julia Korell et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

An Erythroid Enhancer of BCL11A Subject to Genetic Variation Determines Fetal Hemoglobin Level

(2013) D. E. Bauer et al.   SCIENCE

Changes in the properties of normal human red blood cells during in vivo aging

(2012) Robert S. Franco et al.   AMERICAN JOURNAL OF HEMATOLOGY

Optimal conditions for lentiviral transduction of engrafting human CD34+ cells

(2011) N Uchida et al.   GENE THERAPY

Evaluation of red blood cell labelling methods based on a statistical model for red blood cell survival

(2011) Julia Korell et al.   JOURNAL OF THEORETICAL BIOLOGY

Correction of Sickle Cell Disease in Adult Mice by Interference with Fetal Hemoglobin Silencing

(2011) J. Xu et al.   SCIENCE

Dynamics of Mutant Cells in Hierarchical Organized Tissues

(2011) Benjamin Werner et al.   PLoS Computational Biology

Quantitatively different red cell/nucleated cell chimerism in patients with long-term, persistent hematopoietic mixed chimerism after bone marrow transplantation for thalassemia major or sickle cell disease

(2010) M. Andreani et al.   HAEMATOLOGICA

A novel human gamma-globin gene vector for genetic correction of sickle cell anemia in a humanized sickle mouse model: critical determinants for successful correction

(2009) A. Perumbeti et al.   BLOOD

A method for the continuous calculation of the age of labeled red blood cells

(2008) Christopher J. Lindsell et al.   AMERICAN JOURNAL OF HEMATOLOGY

Red cell life span heterogeneity in hematologically normal people is sufficient to alter HbA1c

(2008) R. M. Cohen et al.   BLOOD

Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific RepressorBCL11A

(2008) Vijay G. Sankaran et al.   SCIENCE