期刊
AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS
卷 31, 期 5, 页码 389-394出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/1533317515617546
关键词
peptic ulcer disease; dementia; Taiwan National Health Insurance Research Database
资金
- Taiwan Ministry of Health and Welfare Clinical Trial and Research Center of Excellence [MOHW105-TDU-B-212-133019]
- China Medical University Hospital, Academia Sinica Taiwan Biobank, Stroke Biosignature Project [BM10501010037]
- NRPB Stroke Clinical Trial Consortium [MOST 104-2325-B-039 -005]
- Taiwan Ministry of Science and Technology [MOST103-2314-B-715-001-MY2, MOST104-2314-B-715-003-MY3]
- Mackay Medical College [MMC 1012A10, RD1010061, RD1020038, RD1020047, RD1012B13, RD1031B05, RD1030053, RD1030076, RD1040109]
- Mackay Memorial Hospital [MMH-MM-10304, MMH-MM-10405]
- Tseng-Lien Lin Foundation, Taichung, Taiwan
- Taiwan Brain Disease Foundation, Taipei, Taiwan
- Katsuzo and Kiyo Aoshima Memorial Funds, Japan
- CMU under the Aim for Top University Plan of the Ministry of Education, Taiwan
Objective: We determine the association between dementia and the subsequent peptic ulcer disease (PUD). Methods: We identified patients with diagnosed dementia in the Taiwan National Health Insurance Research Database. A comparison cohort without dementia was frequency-matched by age, sex, and comorbidities, and the occurrence of PUD was evaluated in both cohorts. Results: The dementia and control cohort consisted of 6014 patients with dementia and 17 830 frequency-matched patients without dementia, respectively. The incidence of PUD (hazard ratio, 1.27; 95% confidence interval, 1.18-1.37; P < .001) was higher among patients with dementia. Cox models showed that being female, diabetes mellitus, chronic kidney disease, coronary artery disease, and chronic obstructive pulmonary disease were independent risk factors for PUD in patients with dementia. Conclusion: Dementia might increase the risk of developing PUD.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据
分享论文
