Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans

ATM-dependent phosphorylation of SNEVhPrp19/hPso4 is involved in extending cellular life span and suppression of apoptosis

(2016) Hanna Dellago et al.   Aging-US

The Ras-Erk-ETS-Signaling Pathway Is a Drug Target for Longevity

(2015) Cathy Slack et al.   CELL

Identification of recurrent regulated alternative splicing events across human solid tumors

(2015) Miri Danan-Gotthold et al.   NUCLEIC ACIDS RESEARCH

Structural determinants for alternative splicing regulation of the MAPT pre-mRNA

(2015) Jolanta Lisowiec et al.   RNA Biology

SRSF3 and hnRNP H1 regulate a splicing hotspot ofHER2in breast cancer cells

(2015) Hannah Gautrey et al.   RNA Biology

Ablation of the p16INK4a tumour suppressor reverses ageing phenotypes of klotho mice

(2015) Seidai Sato et al.   Nature Communications

PTBP1 and PTBP2 impaired autoregulation of SRSF3 in cancer cells

(2015) Jihua Guo et al.   Scientific Reports

Posttranscriptional Regulation of Splicing Factor SRSF1 and Its Role in Cancer Cell Biology

(2015) Vânia Gonçalves et al.   Biomed Research International

Evolutionarily Conserved Heterogeneous Nuclear Ribonucleoprotein (hnRNP) A/B Proteins Functionally Interact with Human andDrosophilaTAR DNA-binding Protein 43 (TDP-43)

(2014) Maurizio Romano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Changes in CEBPB expression in circulating leukocytes following eccentric elbow-flexion exercise

(2014) Jamie Blackwell et al.   Journal of Physiological Sciences

Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases

(2014) C. Franceschi et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Accessing Data Resources in the Mouse Phenome Database for Genetic Analysis of Murine Life Span and Health Span

(2014) Molly A. Bogue et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Splicing factor 3B1 hypomethylation is associated with altered SF3B1 transcript expression in older humans

(2014) Alice C. Holly et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Transcriptome-wide Landscape of Pre-mRNA Alternative Splicing Associated with Metastatic Colonization

(2014) Zhi-xiang Lu et al.   MOLECULAR CANCER RESEARCH

Splicing factor hnRNP A2 activates the Ras-MAPK-ERK pathway by controlling A-Raf splicing in hepatocellular carcinoma development

(2014) A. Shilo et al.   RNA

Alternative Splicing Generates Different Parkin Protein Isoforms: Evidences in Human, Rat, and Mouse Brain

(2014) Soraya Scuderi et al.   Biomed Research International

Aging children of long-lived parents experience slower cognitive decline

(2013) Ambarish Dutta et al.   Alzheimers & Dementia

Mice as a Mammalian Model for Research on the Genetics of Aging

(2013) R. Yuan et al.   ILAR JOURNAL

Longer Lived Parents: Protective Associations With Cancer Incidence and Overall Mortality

(2013) Ambarish Dutta et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Changes in splicing factor expression are associated with advancing age in man

(2013) Alice C. Holly et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

(2013) Hong Joo Kim et al.   NATURE

Copy Number Variations in Alternative Splicing Gene Networks Impact Lifespan

(2013) Joseph T. Glessner et al.   PLoS One

Short Structured RNAs with Low GC Content Are Selectively Lost during Extraction from a Small Number of Cells

(2012) Young-Kook Kim et al.   MOLECULAR CELL

Genetic coregulation of age of female sexual maturation and lifespan through circulating IGF1 among inbred mouse strains

(2012) R. Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Evolutionary Landscape of Alternative Splicing in Vertebrate Species

(2012) N. L. Barbosa-Morais et al.   SCIENCE

Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing

(2011) Lorna W. Harries et al.   AGING CELL

CCAAT-enhancer-binding protein-beta expression in vivo is associated with muscle strength

(2011) Lorna W. Harries et al.   AGING CELL

TDP-43: the relationship between protein aggregation and neurodegeneration in amyotrophic lateral sclerosis and frontotemporal lobar degeneration

(2011) Robert H. Baloh   FEBS Journal

Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels

(2009) Rong Yuan et al.   AGING CELL

Genes and gene expression modules associated with caloric restriction and aging in the laboratory mouse

(2009) William R Swindell   BMC GENOMICS