Article
Environmental Sciences
Zhiyu Yang, Shouyi Chen, Si Zhou, Conghui Xu, Chunxia Jing, Chongshan Guo, Xinhong Pan, Lixi Zeng, Lei Tan
Summary: This study evaluated the association between internal exposure to polycyclic aromatic hydrocarbons (PAHs) and urinary iodine concentration with thyroid volume in school-age children in Guangzhou, China. The results showed a significant positive association between urinary hydroxylated PAHs and thyroid volume. Additionally, urinary PAHs were also linked to urinary iodine, and iodine mediated the relationship between PAHs and thyroid volume.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Sandra F. Fernandez, Olga Pardo, Cristina S. Hernandez, Borja Garlito, Vicent Yusa
Summary: The study found a high detection rate of polycyclic aromatic hydrocarbons (PAHs) metabolites in children living in the Valencian Region of Spain, with exposure levels affected by factors such as province of residence, BMI, age, consumption of plastic-wrapped food, and dietary habits. Risk assessment showed that children's daily intake levels were within safe limits, and no potential non-cancer health risks due to PAH exposure were observed.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Environmental Sciences
Senyuan Huang, Qin Li, Hao Liu, Shengtao Ma, Chaoyang Long, Guiying Li, Yingxin Yu
Summary: This study on PAH exposure levels and influencing factors in China found that PAHs have adverse health effects, associated with sampling time, living habits, and regional economic development and energy consumption imbalances. The study also found smoking to be the main factor correlated with PAH concentrations, and inhalation and diet to be the main exposure routes. Naphthalene and phenanthrene were identified as possibly related to lung cancer risk in the Chinese population.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Environmental Sciences
Sandra F. Fernandez, Olga Pardo, Agustin Pastor, Vicent Yusa
Summary: This study analyzed eleven metabolites of PAHs in the urine of 110 lactating women in Spain, finding that naphthalene metabolites had the highest urinary levels. Statistical analysis showed that smoking status and ingestion of certain food groups were the main influencing factors on PAH exposure. Overall, the study did not reveal a significant health risk for Spanish women due to PAH exposure.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Umer Bakali, Jeramy L. R. Baum, Chitvan Killawala, Erin N. Kobetz, Natasha Schaefer Solle, Sapna K. Deo, Alberto J. Caban-Martinez, Leonidas G. Bachas, Sylvia Daunert
Summary: Carcinogens emitted at fire scenes contribute to increased cancer risk in firefighters compared to the general population. This study used passive samplers to investigate the deposition behavior of PAHs emitted by fires, finding significantly higher PAH exposure in biomass fueled fires. These findings can help reduce the carcinogenic risk experienced by emergency personnel at fire scenes.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Environmental Sciences
Xiaoyu Zhang, Zijian Li
Summary: This study combines data from 56 published studies to develop a profile of urinary metabolites of polycyclic aromatic hydrocarbons (PAHs) among the Chinese population in the 2010s. The study finds that the Chinese population is generally exposed to PAHs, with higher exposure levels in the Southern region compared to the Northern region. Adults (45-55 years old) have the highest level of internal PAH exposure. Overall, there is a decreasing trend in the levels of urinary PAH metabolites among the Chinese general population between 2010 and 2018.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Nicolas Sambiagio, Aurelie Berthet, Pascal Wild, Jean -Jacques Sauvain, Reto Auer, Anna Schoeni, Nicolas Rodondi, Martin Feller, Jean -Paul Humair, Ivan Berlin, Florian Breider, Dominique Grandjean, Nancy B. Hopf
Summary: Oxidative stress is associated with exposure to toxicants in air pollution and cigarette smoke, especially PAHs and VOCs. This study found associations between these exposures and oxidative stress biomarkers, and assessed their relative importance.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Chemistry, Multidisciplinary
Xiushang Xu, Amy L. Vonder Haar, Rengo Yoshioka, Qizheng Zhang, Serhii Vasylevskyi, Andrew J. Musser, Akimitsu Narita
Summary: A benzo[rst]pentaphene derivative, BPP-MeOPA, was synthesized and characterized by NMR and single-crystal X-ray analysis. Investigation of its photophysical properties, including transient absorption spectroscopy, revealed improved absorption and emission features from an S-1 state with excitonic and charge-transfer character by introducing MeOPA groups.
CHEMICAL COMMUNICATIONS
(2023)
Article
Environmental Sciences
Jennifer L. A. Keir, Sabit Cakmak, Jules M. Blais, Paul A. White
Summary: Urinary concentrations of PAH metabolites are associated with smoking status, age, and sex, and are influenced by demographic factors in non-smokers such as age, sex, home age, and occupation. The unexplained variation in PAH metabolite levels is likely related to diet. The results can be used to identify remedial measures and design follow-up studies to test hypotheses related to exposure differences empirically.
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
(2021)
Review
Environmental Sciences
Henriqueta Louro, Bruno Costa Gomes, Anne Thoustrup Saber, Anna Laura Iamiceli, Thomas Goen, Kate Jones, Andromachi Katsonouri, Christiana M. Neophytou, Ulla Vogel, Celia Ventura, Axel Oberemm, Radu Corneliu Duca, Mariana F. Fernandez, Nicolas Olea, Tiina Santonen, Susana Viegas, Maria Joao Silva
Summary: This comprehensive review aims to provide regulators and policymakers with a comprehensive overview of occupational exposure to polycyclic aromatic hydrocarbons (PAHs), including the use of exposure and effect biomarkers, as well as the knowledge needs for regulation. The review highlights the importance of advancing harmonized approaches in data and sample collection, as well as the use of appropriate biomarkers in occupational studies to obtain reliable and comparable data on PAH exposure.
Article
Environmental Sciences
Marilia Cristina Oliveira Souza, Bruno Alves Rocha, Joao Paulo Bianchi Ximenez, Paula Picoli Devoz, Anthony Santana, Andres Dobal Campiglia, Fernando Barbosa Jr
Summary: This study aimed to measure levels of polycyclic aromatic hydrocarbons (PAHs) in urine from Brazilian children and provide risk assessment. Naphthalene was found to be the major contributor to children's exposure to PAHs. Children in urban regions had higher PAH exposure and older children had higher concentrations of 2-naphthol, suggesting possible differences in dietary habits. This study provides the first levels of PAHs in Brazilian children.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Environmental Sciences
Elyse Caron-Beaudoin, Pierre Ayotte, Amira Aker, Caty Blanchette, Sylvie Ricard, Veronique Gilbert, Ellen Avard, Melanie Lemire
Summary: This study found that Inuit people are exposed to numerous volatile organic compounds and polycyclic aromatic hydrocarbons. Smoking habit is an important contributor to the elevated levels of benzene and PAHs exposure. Other local sources of exposure need to be further investigated and reduced.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Hongkai Zhu, Maria-Pilar Martinez-Moral, Kurunthachalam Kannan
Summary: The study found that metabolites of polycyclic aromatic hydrocarbons (PAHs) were widely present in urine, with significant inter-individual variability in some metabolites' concentrations, showing association with oxidative stress. Linear mixed-effects analysis revealed a positive correlation between OH-PAH concentrations and oxidative damage to DNA, lipids, and proteins.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Environmental Sciences
Pan Yan, Lingfei Kong, Tuo Qin, Zhonggeng Luo, Xiaona Zhang, Cai Tie
Summary: Using ultra-performance liquid chromatography-high-resolution mass spectrometry (UPLC-HRMS), this study identified the monohydroxyl metabolites of naphthalene, phenanthrene, pyrene, and 9-fluorenone in the urine of low-dose PAH-exposed individuals. The concentrations of these metabolites were monitored for 15 consecutive days, and the results showed that they were strongly correlated with their parent PAH exposure and may serve as potential biomarkers of PAH internal exposure at low doses. This study provides methodological and data support for further health risk studies involving internal exposure to PAHs and other organic pollutants.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Environmental Sciences
Erin R. Wallace, Yu Ni, Christine T. Loftus, Alexis Sullivan, Erin Masterson, Adam A. Szpiro, Drew B. Day, Morgan Robinson, Kurunthachalam Kannan, Fran A. Tylavsky, Sheela Sathyanarayana, Nicole R. Bush, Kaja Z. LeWinn, Catherine J. Karr
Summary: This study found that prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) may have negative impacts on toddler neurodevelopment, with 1-hydroxypyrene associated with elevated risk for neurodevelopmental delay at age 2, while 1-hydroxynaphthalene was associated with lower risk for behavior problems at age 2. Additionally, certain PAH mixtures may affect children's language and cognitive development.
ENVIRONMENT INTERNATIONAL
(2022)