Genetic and pharmacological interventions in the aging motor nervous system slow motor aging and extend life span in C. elegans

Brain–gut communications via distinct neuroendocrine signals bidirectionally regulate longevity inC. elegans

(2018) Bi Zhang et al.   GENES & DEVELOPMENT

The C. elegans Taste Receptor Homolog LITE-1 Is a Photoreceptor

(2016) Jianke Gong et al.   CELL

The Neuronal Kinesin UNC-104/KIF1A Is a Key Regulator of Synaptic Aging and Insulin Signaling-Regulated Memory

(2016) Ling-Bo Li et al.   CURRENT BIOLOGY

Neuronal CRTC-1 Governs Systemic Mitochondrial Metabolism and Lifespan via a Catecholamine Signal

(2015) Kristopher Burkewitz et al.   CELL

Cell nonautonomous activation of flavin-containing monooxygenase promotes longevity and health span

(2015) S. F. Leiser et al.   SCIENCE

C. elegans maximum velocity correlates with healthspan and is maintained in worms with an insulin receptor mutation

(2015) Jeong-Hoon Hahm et al.   Nature Communications

A Genetic Program Promotes C. elegans Longevity at Cold Temperatures via a Thermosensitive TRP Channel

(2013) Rui Xiao et al.   CELL

Functional Aging in the Nervous System Contributes to Age-Dependent Motor Activity Decline in C. elegans

(2013) Jie Liu et al.   Cell Metabolism

Mice with Deficient BK Channel Function Show Impaired Prepulse Inhibition and Spatial Learning, but Normal Working and Spatial Reference Memory

(2013) Marei Typlt et al.   PLoS One

Neurite Sprouting and Synapse Deterioration in the Aging Caenorhabditis elegans Nervous System

(2012) M. L. Toth et al.   JOURNAL OF NEUROSCIENCE

The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity

(2011) Jenni Durieux et al.   CELL

Spontaneous Age-Related Neurite Branching in Caenorhabditis elegans

(2011) E. M. H. Tank et al.   JOURNAL OF NEUROSCIENCE

Genetic analysis of age-dependent defects of the Caenorhabditis elegans touch receptor neurons

(2011) C.-L. Pan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The genetics of ageing

(2010) Cynthia J. Kenyon   NATURE

Enhanced neuronal RNAi in C. elegans using SID-1

(2010) Andrea Calixto et al.   NATURE METHODS

BK channel activation: structural and functional insights

(2010) Urvi S. Lee et al.   TRENDS IN NEUROSCIENCES

Oxidation of potassium channels by ROS: a general mechanism of aging and neurodegeneration?

(2009) Federico Sesti et al.   TRENDS IN CELL BIOLOGY

Identification by machine vision of the rate of motor activity decline as a lifespan predictor in C. elegans

(2008) Ao-Lin Hsu et al.   NEUROBIOLOGY OF AGING

Activation of large-conductance Ca2+-activated K+ channels depresses basal synaptic transmission in the hippocampal CA1 area in APP (swe/ind) TgCRND8 mice

(2008) Hui Ye et al.   NEUROBIOLOGY OF AGING

Caenorhabditis elegans HCF-1 Functions in Longevity Maintenance as a DAF-16 Regulator

(2008) Ji Li et al.   PLOS BIOLOGY