FDISCO: Advanced solvent-based clearing method for imaging whole organs

A three-dimensional single-cell-resolution whole-brain atlas using CUBIC-X expansion microscopy and tissue clearing

(2018) Tatsuya C. Murakami et al.   NATURE NEUROSCIENCE

Multiplex, quantitative cellular analysis in large tissue volumes with clearing-enhanced 3D microscopy (Ce3D)

(2017) Weizhe Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Precise Cerebral Vascular Atlas in Stereotaxic Coordinates of Whole Mouse Brain

(2017) Benyi Xiong et al.   Frontiers in Neuroanatomy

Chemical Principles in Tissue Clearing and Staining Protocols for Whole-Body Cell Profiling

(2016) Kazuki Tainaka et al.   Annual Review of Cell and Developmental Biology

Clearing of fixed tissue: a review from a microscopist’s perspective

(2016) Ludovico Silvestri et al.   JOURNAL OF BIOMEDICAL OPTICS

Fully Automated Evaluation of Total Glomerular Number and Capillary Tuft Size in Nephritic Kidneys Using Lightsheet Microscopy

(2016) Anika Klingberg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Multiplexed and scalable super-resolution imaging of three-dimensional protein localization in size-adjustable tissues

(2016) Taeyun Ku et al.   NATURE BIOTECHNOLOGY

Shrinkage-mediated imaging of entire organs and organisms using uDISCO

(2016) Chenchen Pan et al.   NATURE METHODS

Clarifying Tissue Clearing

(2015) Douglas S. Richardson et al.   CELL

Saturated Reconstruction of a Volume of Neocortex

(2015) Narayanan Kasthuri et al.   CELL

ScaleS: an optical clearing palette for biological imaging

(2015) Hiroshi Hama et al.   NATURE NEUROSCIENCE

Fluorescent-Protein Stabilization and High-Resolution Imaging of Cleared, Intact Mouse Brains

(2015) Martin K. Schwarz et al.   PLoS One

Whole-Brain Imaging with Single-Cell Resolution Using Chemical Cocktails and Computational Analysis

(2014) Etsuo A. Susaki et al.   CELL

Single-Cell Phenotyping within Transparent Intact Tissue through Whole-Body Clearing

(2014) Bin Yang et al.   CELL

iDISCO: A Simple, Rapid Method to Immunolabel Large Tissue Samples for Volume Imaging

(2014) Nicolas Renier et al.   CELL

Neural Networks of the Mouse Neocortex

(2014) Brian Zingg et al.   CELL

Whole-Body Imaging with Single-Cell Resolution by Tissue Decolorization

(2014) Kazuki Tainaka et al.   CELL

A mesoscale connectome of the mouse brain

(2014) Seung Wook Oh et al.   NATURE

Recent progress in tissue optical clearing

(2013) Dan Zhu et al.   Laser & Photonics Reviews

Structural and molecular interrogation of intact biological systems

(2013) Kwanghun Chung et al.   NATURE

Serial two-photon tomography for automated ex vivo mouse brain imaging

(2012) Timothy Ragan et al.   NATURE METHODS

Three-dimensional imaging of solvent-cleared organs using 3DISCO

(2012) Ali Ertürk et al.   Nature Protocols

Chemical Clearing and Dehydration of GFP Expressing Mouse Brains

(2012) Klaus Becker et al.   PLoS One

Cortical representations of olfactory input by trans-synaptic tracing

(2010) Kazunari Miyamichi et al.   NATURE

Temperature influence on fluorescence intensity and enzyme activity of the fusion protein of GFP and hyperthermophilic xylanase

(2009) Chong Zhang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Denaturation studies reveal significant differences between GFP and blue fluorescent protein

(2009) Ibtesam A. Saeed et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES