Additivity of inhibitory effects in multidrug combinations

Efficient measurement and factorization of high-order drug interactions in Mycobacterium tuberculosis

(2017) Murat Cokol et al.   Science Advances

Chemogenomics and orthology‐based design of antibiotic combination therapies

(2016) Sriram Chandrasekaran et al.   Molecular Systems Biology

Antimicrobial combinations: Bliss independence and Loewe additivity derived from mechanistic multi-hit models

(2016) Desiree Y. Baeder et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Prediction of multidimensional drug dose responses based on measurements of drug pairs

(2016) Anat Zimmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multidrug evolutionary strategies to reverse antibiotic resistance

(2015) M. Baym et al.   SCIENCE

Collateral sensitivity of antibiotic-resistant microbes

(2015) Csaba Pál et al.   TRENDS IN MICROBIOLOGY

What is synergy? The Saariselkä agreement revisited

(2015) Jing Tang et al.   Frontiers in Pharmacology

grofit: Fitting Biological Growth Curves withR

(2015) Matthias Kahm et al.   Journal of Statistical Software

Use of Collateral Sensitivity Networks to Design Drug Cycling Protocols That Avoid Resistance Development

(2013) L. Imamovic et al.   Science Translational Medicine

Mechanism-independent method for predicting response to multidrug combinations in bacteria

(2012) Kevin Wood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic exploration of synergistic drug pairs

(2011) M. Cokol et al.   Molecular Systems Biology

What counters antibiotic resistance in nature?

(2011) Remy Chait et al.   Nature Chemical Biology

Structure and Evolution of Streptomyces Interaction Networks in Soil and In Silico

(2011) Kalin Vetsigian et al.   PLOS BIOLOGY

Nonoptimal Microbial Response to Antibiotics Underlies Suppressive Drug Interactions

(2009) Tobias Bollenbach et al.   CELL

The natural history of antibiotics

(2009) Jon Clardy et al.   CURRENT BIOLOGY

Synergistic drug combinations tend to improve therapeutically relevant selectivity

(2009) Joseph Lehár et al.   NATURE BIOTECHNOLOGY

Drug interactions and the evolution of antibiotic resistance

(2009) Pamela J. Yeh et al.   NATURE REVIEWS MICROBIOLOGY

Accelerated evolution of resistance in multidrug environments

(2008) M. Hegreness et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drug interactions modulate the potential for evolution of resistance

(2008) J.-B. Michel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA