Circulating Y-RNAs in Extracellular Vesicles and Ribonucleoprotein Complexes; Implications for the Immune System

Immune stimuli shape the small non-coding transcriptome of extracellular vesicles released by dendritic cells

(2018) Tom A. P. Driedonks et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Extracellular vesicles: important collaborators in cancer progression

(2018) Shinya Sato et al.   Essays in Biochemistry

HuD Is a Neural Translation Enhancer Acting on mTORC1-Responsive Genes and Counteracted by the Y3 Small Non-coding RNA

(2018) Toma Tebaldi et al.   MOLECULAR CELL

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular interactions at the surface of extracellular vesicles

(2018) Edit I. Buzás et al.   Seminars in Immunopathology

Apoptotic Cell-Derived Extracellular Vesicles: More Than Just Debris

(2018) Sarah Caruso et al.   Frontiers in Immunology

Non-coding Y RNAs associate with early replicating euchromatin in concordance with the origin recognition complex

(2017) Eyemen Kheir et al.   JOURNAL OF CELL SCIENCE

Emergent properties of extracellular vesicles: a holistic approach to decode the complexity of intercellular communication networks

(2017) Yong Song Gho et al.   Molecular BioSystems

EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research

(2017) Jan Van Deun et al.   NATURE METHODS

Why the need and how to approach the functional diversity of extracellular vesicles

(2017) Mercedes Tkach et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Broad role for YBX1 in defining the small noncoding RNA composition of exosomes

(2017) Matthew J. Shurtleff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid RNase L–driven arrest of protein synthesis in the dsRNA response without degradation of translation machinery

(2017) Jesse Donovan et al.   RNA

RNY (YRNA)-derived small RNAs regulate cell death and inflammation in monocytes/macrophages

(2017) Zoheir Hizir et al.   Cell Death & Disease

Coding and noncoding landscape of extracellular RNA released by human glioma stem cells

(2017) Zhiyun Wei et al.   Nature Communications

Total Extracellular Small RNA Profiles from Plasma, Saliva and Urine of Healthy Subjects

(2017) Ashish Yeri et al.   Scientific Reports

Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

(2016) Mercedes Tkach et al.   CELL

Extracellular vesicles in cardiovascular disease: are they Jedi or Sith?

(2016) Xabier Osteikoetxea et al.   JOURNAL OF PHYSIOLOGY-LONDON

Extracellular vesicles and viruses: Are they close relatives?

(2016) Esther Nolte-‘t Hoen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of the human immunodeficiency virus-1 RNA packageome

(2016) Matthew J. Eckwahl et al.   RNA

The Host RNAs in Retroviral Particles

(2016) Alice Telesnitsky et al.   Viruses-Basel

Host RNA Packaging by Retroviruses: A Newly Synthesized Story

(2016) Matthew J. Eckwahl et al.   mBio

Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction

(2016) Matthew J Shurtleff et al.   eLife

Regulatory consequences of neuronal ELAV-like protein binding to coding and non-coding RNAs in human brain

(2016) Claudia Scheckel et al.   eLife

Platelets confound the measurement of extracellular miRNA in archived plasma

(2016) Adam J. Mitchell et al.   Scientific Reports

RNY-derived small RNAs as a signature of coronary artery disease

(2015) Emanuela Repetto et al.   BMC Medicine

In Vivo Imaging Reveals Extracellular Vesicle-Mediated Phenocopying of Metastatic Behavior

(2015) Anoek Zomer et al.   CELL

Association of MicroRNAs and YRNAs With Platelet FunctionNovelty and Significance

(2015) Dorothee Kaudewitz et al.   CIRCULATION RESEARCH

The RNA-binding protein HuR/ELAVL1 regulates IFN-β mRNA abundance and the type I IFN response

(2015) Barbara Herdy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Y3** ncRNA promotes the 3′ end processing of histone mRNAs

(2015) Marcel Köhn et al.   GENES & DEVELOPMENT

A retrovirus packages nascent host noncoding RNAs from a novel surveillance pathway

(2015) Matthew J. Eckwahl et al.   GENES & DEVELOPMENT

Functional roles of non-coding Y RNAs

(2015) Madzia P. Kowalski et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Assessment of small RNA sorting into different extracellular fractions revealed by high-throughput sequencing of breast cell lines

(2015) J. P. Tosar et al.   NUCLEIC ACIDS RESEARCH

Small RNA deep sequencing discriminates subsets of extracellular vesicles released by melanoma cells – Evidence of unique microRNA cargos

(2015) Taral R Lunavat et al.   RNA Biology

Extracellular vesicle-mediated transfer of processed and functional RNY5 RNA

(2015) Sudipto K. Chakrabortty et al.   RNA

HIV-1 and two avian retroviral 5′ untranslated regions bind orthologous human and chicken RNA binding proteins

(2015) Matthew Stake et al.   VIROLOGY

Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters

(2015) Charles P. Lai et al.   Nature Communications

Exosome-delivered microRNAs modulate the inflammatory response to endotoxin

(2015) Margaret Alexander et al.   Nature Communications

Promiscuous RNA Binding Ensures Effective Encapsidation of APOBEC3 Proteins by HIV-1

(2015) Luis Apolonia et al.   PLoS Pathogens

Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment

(2015) Kirsten Ridder et al.   OncoImmunology

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions

(2014) L. Vojtech et al.   NUCLEIC ACIDS RESEARCH

Assessing the gene regulatory properties of Argonaute-bound small RNAs of diverse genomic origin

(2014) Daniel W. Thomson et al.   NUCLEIC ACIDS RESEARCH

pY RNA1-s2: A Highly Retina-Enriched Small RNA That Selectively Binds to Matrin 3 (Matr3)

(2014) Fumiyoshi Yamazaki et al.   PLoS One

Bacterial noncoding Y RNAs are widespread and mimic tRNAs

(2014) Xinguo Chen et al.   RNA

Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

(2014) Amy H. Buck et al.   Nature Communications

Extracellular Vesicle-Mediated Transfer of Genetic Information between the Hematopoietic System and the Brain in Response to Inflammation

(2014) Kirsten Ridder et al.   PLOS BIOLOGY

“Small Talk” in the Innate Immune System via RNA-Containing Extracellular Vesicles

(2014) Susanne G. van der Grein et al.   Frontiers in Immunology

An RNA Degradation Machine Sculpted by Ro Autoantigen and Noncoding RNA

(2013) Xinguo Chen et al.   CELL

Ro60 Requires Y3 RNA for Cell Surface Exposure and Inflammation Associated with Cardiac Manifestations of Neonatal Lupus

(2013) J. H. Reed et al.   JOURNAL OF IMMUNOLOGY

Biases in small RNA deep sequencing data

(2013) Carsten A. Raabe et al.   NUCLEIC ACIDS RESEARCH

5′-YRNA fragments derived by processing of transcripts from specific YRNA genes and pseudogenes are abundant in human serum and plasma

(2013) Joseph M. Dhahbi et al.   PHYSIOLOGICAL GENOMICS

Non-coding Y RNAs as tethers and gates

(2013) Sandra L Wolin et al.   RNA Biology

Biogenesis of Y RNA-derived small RNAs is independent of the microRNA pathway

(2012) Francisco Esteban Nicolas et al.   FEBS LETTERS

Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells

(2012) Shayne A. Bellingham et al.   NUCLEIC ACIDS RESEARCH

Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions

(2012) Esther N. M. Nolte-’t Hoen et al.   NUCLEIC ACIDS RESEARCH

Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation

(2012) Hina Kalra et al.   PLOS BIOLOGY

Are the Ro RNP-associated Y RNAs concealing microRNAs? Y RNA-derived miRNAs may be involved in autoimmunity

(2011) Anja P. M. Verhagen et al.   BIOESSAYS

Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes

(2011) A. Montecalvo et al.   BLOOD

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

(2011) Kasey C. Vickers et al.   NATURE CELL BIOLOGY

Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

(2011) J. D. Arroyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The zipcode-binding protein ZBP1 influences the subcellular location of the Ro 60-kDa autoantigen and the noncoding Y3 RNA

(2011) S. Sim et al.   RNA

Ro60-Associated Single-Stranded RNA Links Inflammation with Fetal Cardiac Fibrosis via Ligation of TLRs: A Novel Pathway to Autoimmune-Associated Heart Block

(2010) Robert M. Clancy et al.   JOURNAL OF IMMUNOLOGY

Nematode sbRNAs: Homologs of Vertebrate Y RNAs

(2010) Ilenia Boria et al.   JOURNAL OF MOLECULAR EVOLUTION

Proteomics Analysis of Bladder Cancer Exosomes

(2010) Joanne L. Welton et al.   MOLECULAR & CELLULAR PROTEOMICS

Microvesicles Derived from Adult Human Bone Marrow and Tissue Specific Mesenchymal Stem Cells Shuttle Selected Pattern of miRNAs

(2010) Federica Collino et al.   PLoS One

Near-infrared (NIR) dye-labeled RNAs identify binding of ZBP1 to the noncoding Y3-RNA

(2010) M. Kohn et al.   RNA

Y-box protein-1 is actively secreted through a non-classical pathway and acts as an extracellular mitogen

(2009) Björn C Frye et al.   EMBO REPORTS

PD-1 signaling in primary T cells

(2009) James L. Riley   IMMUNOLOGICAL REVIEWS

Packaging of Host mY RNAs by Murine Leukemia Virus May Occur Early in Y RNA Biogenesis

(2009) E. L. Garcia et al.   JOURNAL OF VIROLOGY

A conserved motif of vertebrate Y RNAs essential for chromosomal DNA replication

(2009) T. J. Gardiner et al.   RNA

Exosomes Packaging APOBEC3G Confer Human Immunodeficiency Virus Resistance to Recipient Cells

(2008) A. K. Khatua et al.   JOURNAL OF VIROLOGY

Single-stranded RNA facilitates nucleocapsid: APOBEC3G complex formation

(2008) H. P. Bogerd et al.   RNA