Article
Multidisciplinary Sciences
Victoria Soares Soeiro, Ricardo Silva-Carvalho, Daniela Martins, Pier Parpot, Denise Grotto, Marco Vinicius Chaud, Francisco Miguel Portela da Gama, Angela F. Jozala
Summary: Nanocomplexes systems made up natural polymers have pharmacotechnical advantages by increasing water solubility and decreasing drug toxicity. By covering Amphotericin B with nanocrystals from bacterial cellulose, the nanocomplexes showed improved biocompatibility and reduced cytotoxicity, making them a potentially non-toxic alternative for drug delivery.
SCIENTIFIC REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Baramee Chanabodeechalermrung, Tanpong Chaiwarit, Sarana Rose Sommano, Pornchai Rachtanapun, Nutthapong Kantrong, Chuda Chittasupho, Pensak Jantrawut
Summary: Composite bacterial cellulose hydrogel with PHMB showed improved physicochemical properties and excellent biocompatibility, demonstrating potential as a dual crosslinked ion-based hydrogel for wound dressing with anti-bacterial activity.
Article
Spectroscopy
Mari F. Nicolas, Jayr H. Marin, Giordano T. Paganoto, Rafaella F. Fernandes, Marcia L. A. Temperini
Summary: This study presents a new SERS and SEF platform approach using substrates composed of alginate-stabilized silver nanoparticles encapsulated in calcium alginate hydrogel beads. The distance between probe molecules and metallic nanoparticles, determined by electrostatic repulsion or attraction between charged dyes and carboxylate groups of alginate, defines the SERS or SEF effect. The results demonstrate the detection of SEF effect with IR-820 dye in the near-infrared and visible regions, as well as the SERRS effect and fluorescence quenching with cationic dye in the same AgALGbeads substrate.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Biochemical Research Methods
Tarik Abdelkareem Mostafa Amer, Sathyadevi Palanisamy, Pamela Berilyn So, Priya Vijayaraghavan, Shey-Cherng Tzou, Tsai-Te Lu, Chia-Her Lin, Yun-Ming Wang
Summary: The use of MOF-based nanomaterials in bioapplications has increased due to their biocompatibility, drug degradation, tunable porosity, and intrinsic biodegradability. Bimetallic MOFs embedded with and without folic acid were synthesized and used for tissue sealing and repairing incisional wound sites in mice models. These materials displayed antibacterial properties and enhanced wound healing rates, and also showed potential for cell migration and angiogenesis.
BIOCONJUGATE CHEMISTRY
(2023)
Article
Biophysics
Natalia Czaplicka, Donata Konopacka-Lyskawa, Agata Nowotnik, Aleksandra Mielewczyk-Gryn, Marcin Lapinski, Rafal Bray
Summary: This paper investigates the effects of rhamnolipids presence on the precipitation of CaCO3 in alginate hydrogel. It discusses the characteristics of the formed particles and proposes a mechanism for CaCO3 precipitation in alginate hydrogel containing rhamnolipids.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Biochemistry & Molecular Biology
Lijing Xu, Kongyin Zhao, Junping Miao, Zhenhao Yang, Zhiwei Li, Lei Zhao, Hongxian Su, Ligang Lin, Yunxia Hu
Summary: In this study, silver nanoparticles were synthesized with BSA and CMCS to improve the mechanical property, thermal stability, antibacterial property, and filtration efficiency of CaAlg membrane. The results showed that CMCS significantly enhanced the mechanical property and thermal stability of the composite membrane, while AgNPs endowed the composite membrane with excellent antibacterial property. The addition of VF-PET as the support layer further improved the filtration flux and mechanical property of the composite membrane.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
Shengbo Li, Xuemei Wang, Jing Chen, Jiahe Guo, Meng Yuan, Gui Wan, Chengqi Yan, Wenqing Li, Hans-Guenther Machens, Yuval Rinkevich, Xiaofan Yang, Heng Song, Zhenbing Chen
Summary: Chronic non-healing diabetic wounds and ulcers are a major challenge in the medical field. In this study, a hydrogel with pro-angiogenesis and antibacterial properties was developed, showing potential clinical application in refractory wounds.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Multidisciplinary
Ming Yan, Junfeng Shi, Song Tang, Guohang Zhou, Jiexiang Zeng, Yixin Zhang, Hong Zhang, Yue Yu, Jing Guo
Summary: This study successfully prepared a high-strength and high-toughness medical film with a dynamically united CA/CMCS dual network structure by utilizing PDA, demonstrating excellent mechanical properties and water absorption performance, suggesting promising applications in the medical field.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Polymer Science
Zehua Li, Amanda K. Pearce, Andrew P. Dove, Rachel K. O'Reilly
Summary: This study utilized a crystallization-driven self-assembly method to prepare one-dimensional cylindrical nanoparticles with controlled lengths to improve the mechanical performance of alginate-based hydrogels. The inclusion of these cylindrical structures increased the strength of the hydrogel under shear and resulted in a 37% improvement in strain at flow point when loaded with 500 nm cylindrical micelles. Overall, the one-dimensional cylindrical nanoparticles formed through CDSA show promise as fibrillar collagen mimics for ECM scaffold models.
Article
Engineering, Chemical
Yue Zhang, Kongyin Zhao, Zhenhao Yang, Zhijian Zhang, Zhilong Guo, Rongrong Chu, Wei Zhang, Wenxiong Shi, Jiacheng Li, Ziyi Li, Haiyi Liu, Anhou Xu, Xi Chen
Summary: The study developed high-performance CaAlg and BaAlg composite membranes using materials such as PET, showing excellent separation properties for molecules and ions, providing a new idea for efficient and economical membrane materials.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Materials Science, Biomaterials
Hongyu Wang, Chaonan Li, Qihang Wu, Hui Wen, Tingting Sun, Zhigang Xie
Summary: Due to the constant evolution of antibiotic-resistant bacteria, novel antibacterial materials or methods are urgently needed. In this study, BODIPY-TMA nanoparticles showed enhanced antibacterial effect and were able to prevent and destroy biofilms.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Article
Chemistry, Applied
Valerie Ow, Jun Jie Chang, Wai Hon Chooi, Yi Jian Boo, Rebekah P. T. Tan, Joey H. M. Wong, Bhav Harshad Parikh, Xinyi Su, Shi Yan Ng, Xian Jun Loh, Kun Xue
Summary: Hydrogels with multiple modes of crosslinking, such as the EPC-Alg hydrogel discussed in this study, offer improved control over properties like mechanical strength through the use of multiple stimuli, in this case temperature and Ca2+. These orthogonally crosslinked hydrogels are non-toxic to cells and have fully reversible crosslinks, allowing for modulation of gel strength by selectively removing one or both stimuli. The EPC-Alg hydrogel showed tunable modulation of thermal stability, stiffness, and gelation temperatures, and demonstrated feasibility in cell-based biomedical applications including cell encapsulation and cell therapy.
CARBOHYDRATE POLYMERS
(2023)
Article
Chemistry, Multidisciplinary
Seoyoon Song, Huisoo Jang, Woojin Jeong, Jiwook Shim, Sun Min Kim, Tae-Joon Jeon
Summary: In this study, a calcium-alginate polymer was used to maximize the utility of a PDA-based hydrogel-type sensor and it was found that the sensor is hypersensitive to temperature increases at a lower temperature range. The characterization of potential factors, gelation periods, and gelation agents related to the sensitivity of the so-called PDA-alginate hydrogel was reported. These findings are expected to be applicable in future research on industrially applicable developments for cold-chain delivery systems, temperature-sensitive chemicals, or food. Furthermore, the materials can provide a history of temperature changes as the corresponding color does not revert back even after the temperature decreases to the normal range.
KOREAN JOURNAL OF CHEMICAL ENGINEERING
(2023)
Article
Polymer Science
Cesar Barrientos-Sanhueza, Danny Cargnino-Cisternas, Alvaro Diaz-Barrera, Italo F. Cuneo
Summary: This study investigated the hydro-mechanical behavior of different soils media treated with Ca-bacterial alginate hydrogel. The results showed that increasing kaolinite and water content can improve the yield stress and aggregate stability of the treated soils. Temperature also played a role in the gelation capacity of the hydrogel. Adding kaolinite decreased the saturated hydraulic conductivity of the soils.
Article
Biotechnology & Applied Microbiology
Phasuwit P. Phatchayawat, Arnon Khamkeaw, Supansa Yodmuang, Muenduen Phisalaphong
Summary: Biopolymers of bacterial cellulose, chitosan, alginate and gelatin were combined to fabricate 3D hydrogel scaffolds for tissue engineering. The composite scaffolds exhibited good architecture and biocompatibility, making them suitable for cartilage tissue engineering applications.
BIOCHEMICAL ENGINEERING JOURNAL
(2022)
