期刊
ADDICTION BIOLOGY
卷 22, 期 4, 页码 885-897出版社
WILEY
DOI: 10.1111/adb.12378
关键词
ICD-11; 'impulse control disorder'; 'Pathological Gambling'; reclassification; 'substance-related and addictive disorder'
资金
- Ministry for Work and Social Affairs (Ministerium fur Arbeit und Sozialordnung, Familien und Senioren)
- BadenWurttemberg, Germany [53-5072-7.1]
- CASAColumbia
- National Center for Responsible Gaming (Center of Excellence grant)
- Connecticut Department of Mental Health and Addictive Services
- NIDA [P20 DA027844, R01 DA035058, P50 DA09241]
- Ironwood
- Lundbeck
- Shire
- INSYS
- RiverMend Health
- Mohegan Sun Casino
- National Center for Responsible Gaming
- National Center for Responsible Pfizer
- National Institutes of Health
In light of the upcoming eleventh edition of the International Classification of Diseases (ICD-11), the question arises as to the most appropriate classification of 'Pathological Gambling' ('PG'). Some academic opinion favors leaving PG in the 'Impulse Control Disorder' ('ICD') category, as in ICD-10, whereas others argue that new data especially from the neurobiological area favor allocating it to the category of 'Substance-related and Addictive Disorders' ('SADs'), following the decision in the fifth revision of the Diagnostic and Statistical Manual of Mental Disorders. The current review examines important findings in relation to PG, with the aim of enabling a well-informed decision to be made with respect to the classification of PG as a SAD or ICD in ICD-11. Particular attention is given to cognitive deficits and underlying neurobiological mechanisms that play a role in SADs and ICDs. These processes are impulsivity, compulsivity, reward/punishment processing and decision-making. In summary, the strongest arguments for subsuming PG under a larger SAD category relate to the existence of similar diagnostic characteristics; the high co-morbidity rates between the disorders; their common core features including reward-related aspects (positive reinforcement: behaviors are pleasurable at the beginning which is not the case for ICDs); the findings that the same brain structures are involved in PG and SADs, including the ventral striatum. Research on compulsivity suggests a relationship with PG and SAD, particularly in later stages of the disorders. Although research is limited for ICDs, current data do not support continuing to classify PG as an ICD.
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