Matrix Remodeling Enhances the Differentiation Capacity of Neural Progenitor Cells in 3D Hydrogels

Engineering Hydrogel Microenvironments to Recapitulate the Stem Cell Niche

(2018) Christopher M. Madl et al.   Annual Review of Biomedical Engineering

Bioengineering strategies to accelerate stem cell therapeutics

(2018) Christopher M. Madl et al.   NATURE

Maintenance of neural progenitor cell stemness in 3D hydrogels requires matrix remodelling

(2017) Christopher M. Madl et al.   NATURE MATERIALS

Bringing Neural Cell Therapies to the Clinic: Past and Future Strategies

(2017) Stefan Irion et al.   Molecular Therapy-Methods & Clinical Development

Bio-Orthogonally Crosslinked, Engineered Protein Hydrogels with Tunable Mechanics and Biochemistry for Cell Encapsulation

(2016) Christopher M. Madl et al.   ADVANCED FUNCTIONAL MATERIALS

Dimensionality and spreading influence MSC YAP/TAZ signaling in hydrogel environments

(2016) Steven R. Caliari et al.   BIOMATERIALS

Designer matrices for intestinal stem cell and organoid culture

(2016) Nikolce Gjorevski et al.   NATURE

N-cadherin adhesive interactions modulate matrix mechanosensing and fate commitment of mesenchymal stem cells

(2016) Brian D. Cosgrove et al.   NATURE MATERIALS

A practical guide to hydrogels for cell culture

(2016) Steven R Caliari et al.   NATURE METHODS

Dynamics of Mechanosensitive Neural Stem Cell Differentiation

(2016) Sebastian Rammensee et al.   STEM CELLS

The Hippo pathway member YAP enhances human neural crest cell fate and migration

(2016) Christopher J. Hindley et al.   Scientific Reports

Matrix RGD ligand density and L1CAM-mediated Schwann cell interactions synergistically enhance neurite outgrowth

(2015) Nicole H. Romano et al.   Acta Biomaterialia

YAP/TAZ enhance mammalian embryonic neural stem cell characteristics in a Tead-dependent manner

(2015) Dasol Han et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Rho-Signaling-Directed YAP/TAZ Activity Underlies the Long-Term Survival and Expansion of Human Embryonic Stem Cells

(2015) Masatoshi Ohgushi et al.   Cell Stem Cell

Biodegradable Nanotopography Combined with Neurotrophic Signals Enhances Contact Guidance and Neuronal Differentiation of Human Neural Stem Cells

(2015) Kisuk Yang et al.   MACROMOLECULAR BIOSCIENCE

The regulation and function of YAP transcription co-activator

(2014) C. Zhu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Human Pluripotent Stem Cell Culture: Considerations for Maintenance, Expansion, and Therapeutics

(2014) Kevin G. Chen et al.   Cell Stem Cell

Hippo/YAP-mediated rigidity-dependent motor neuron differentiation of human pluripotent stem cells

(2014) Yubing Sun et al.   NATURE MATERIALS

Mechanical memory and dosing influence stem cell fate

(2014) Chun Yang et al.   NATURE MATERIALS

Substratum-induced differentiation of human pluripotent stem cells reveals the coactivator YAP is a potent regulator of neuronal specification

(2014) S. Musah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use of differentiated pluripotent stem cells in replacement therapy for treating disease

(2014) I. J. Fox et al.   SCIENCE

Hydrogel Design of Experiments Methodology to Optimize Hydrogel for iPSC-NPC Culture

(2014) Jonathan Lam et al.   Advanced Healthcare Materials

The Effects of Topographical Patterns and Sizes on Neural Stem Cell Behavior

(2013) Lin Qi et al.   PLoS One

Design of three-dimensional engineered protein hydrogels for tailored control of neurite growth

(2012) Kyle J. Lampe et al.   Acta Biomaterialia

Multifunctional Materials through Modular Protein Engineering

(2012) Rebecca L. DiMarco et al.   ADVANCED MATERIALS

The effect of injectable gelatin-hydroxyphenylpropionic acid hydrogel matrices on the proliferation, migration, differentiation and oxidative stress resistance of adult neural stem cells

(2012) Teck Chuan Lim et al.   BIOMATERIALS

Neural stem cells encapsulated in a functionalized self-assembling peptide hydrogel for brain tissue engineering

(2012) Tzu-Yun Cheng et al.   BIOMATERIALS

Wnt/β-Catenin Signaling Regulates Yes-associated Protein (YAP) Gene Expression in Colorectal Carcinoma Cells

(2012) Wesley M. Konsavage et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of mouse embryonic stem cell self-renewal by a Yes-YAP-TEAD2 signaling pathway downstream of LIF

(2011) C. Tamm et al.   JOURNAL OF CELL SCIENCE

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Yes-Associated Protein 65 (YAP) Expands Neural Progenitors and Regulates Pax3 Expression in the Neural Plate Border Zone

(2011) Stephen T. Gee et al.   PLoS One

E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components

(2011) N.-G. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rho GTPases Mediate the Mechanosensitive Lineage Commitment of Neural Stem Cells

(2011) Albert J. Keung et al.   STEM CELLS

Controlled Release of Neurotrophin-3 and Platelet-Derived Growth Factor from Fibrin Scaffolds Containing Neural Progenitor Cells Enhances Survival and Differentiation into Neurons in a Subacute Model of SCI

(2010) Philip J. Johnson et al.   CELL TRANSPLANTATION

The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation

(2010) I. Lian et al.   GENES & DEVELOPMENT

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF -TRCP

(2010) B. Zhao et al.   GENES & DEVELOPMENT

Stem cell therapies for spinal cord injury

(2010) Vibhu Sahni et al.   Nature Reviews Neurology

The influence of hydrogel modulus on the proliferation and differentiation of encapsulated neural stem cells

(2009) Akhilesh Banerjee et al.   BIOMATERIALS

Hydrogels as extracellular matrix mimics for 3D cell culture

(2009) Mark W. Tibbitt et al.   BIOTECHNOLOGY AND BIOENGINEERING

The effect of immobilized platelet derived growth factor AA on neural stem/progenitor cell differentiation on cell-adhesive hydrogels

(2008) Yukie Aizawa et al.   BIOMATERIALS

Substrate Modulus Directs Neural Stem Cell Behavior

(2008) Krishanu Saha et al.   BIOPHYSICAL JOURNAL

YAP regulates neural progenitor cell number via the TEA domain transcription factor

(2008) X. Cao et al.   GENES & DEVELOPMENT

Independent tuning of multiple biomaterial properties using protein engineering

(2008) Karin S. Straley et al.   Soft Matter