CD24 identifies nucleus pulposus progenitors/notochordal cells for disc regeneration

SHH-Dependent Knockout of HIF-1 Alpha Accelerates the Degenerative Process in Mouse Intervertebral Disc

(2017) W-J. Wu et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

IL-1β increases asporin expression via the NF-κB p65 pathway in nucleus pulposus cells during intervertebral disc degeneration

(2017) Shengjie Wang et al.   Scientific Reports

Whole Transcriptome Analysis of Notochord-Derived Cells during Embryonic Formation of the Nucleus Pulposus

(2017) Sun H. Peck et al.   Scientific Reports

Spatiotemporal analysis of putative notochordal cell markers reveals CD24 and keratins 8, 18, and 19 as notochord-specific markers during early human intervertebral disc development

(2016) Ricardo Rodrigues-Pinto et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Angiopoietin-1 receptor Tie2 distinguishes multipotent differentiation capability in bovine coccygeal nucleus pulposus cells

(2016) Adel Tekari et al.   Stem Cell Research & Therapy

Stem cell therapy for intervertebral disc regeneration: obstacles and solutions

(2015) Daisuke Sakai et al.   Nature Reviews Rheumatology

Differentiation of Human Ligamentum Flavum Stem Cells Toward Nucleus Pulposus-Like Cells Induced by Coculture System and Hypoxia

(2015) Xiao-Bo Han et al.   SPINE

An understanding of intervertebral disc development, maturation and cell phenotype provides clues to direct cell-based tissue regeneration therapies for disc degeneration

(2014) Ricardo Rodrigues-Pinto et al.   EUROPEAN SPINE JOURNAL

Tracing notochord-derived cells using a Noto-cre mouse: implications for intervertebral disc development

(2011) M. R. McCann et al.   Disease Models & Mechanisms

Non-specific low back pain

(2011) Federico Balagué et al.   LANCET

Notochordal cells protect nucleus pulposus cells from degradation and apoptosis: implications for the mechanisms of intervertebral disc degeneration

(2011) W Erwin et al.   ARTHRITIS RESEARCH & THERAPY

Exploiting notochord cells for stem cell-based regeneration of the intervertebral disc

(2011) Matthew R. McCann et al.   Journal of Cell Communication and Signaling

Immunohistochemical identification of notochordal markers in cells in the aging human lumbar intervertebral disc

(2010) Christoph Weiler et al.   EUROPEAN SPINE JOURNAL

Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α

(2008) Patrick J. Pollard et al.   BIOCHEMICAL JOURNAL

Cell transplantation in lumbar spine disc degeneration disease

(2008) C. Hohaus et al.   EUROPEAN SPINE JOURNAL

The cellular pathobiology of the degenerate intervertebral disc and discogenic back pain

(2008) A. J. Freemont   RHEUMATOLOGY