Sortilin in Glucose Homeostasis: From Accessory Protein to Key Player?

Transcriptional control of intestinal cholesterol absorption, adipose energy expenditure and lipid handling by Sortilin

(2018) Sumihiko Hagita et al.   Scientific Reports

Sortilin 1 knockout alters basal adipose glucose metabolism but not diet-induced obesity in mice

(2017) Jibiao Li et al.   FEBS LETTERS

ProNGF, but Not NGF, Switches from Neurotrophic to Apoptotic Activity in Response to Reductions in TrkA Receptor Levels

(2017) Maria Ioannou et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sortilin 1 Modulates Hepatic Cholesterol Lipotoxicity in Mice via Functional Interaction with Liver Carboxylesterase 1

(2016) Jibiao Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fine tuning of insulin secretion by release of nerve growth factor from mouse and human islet β-cells

(2016) Attilio Pingitore et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

An obligatory role for neurotensin in high-fat-diet-induced obesity

(2016) Jing Li et al.   NATURE

Potentiation of Calcium Influx and Insulin Secretion in Pancreatic Beta Cell by the Specific TREK-1 Blocker Spadin

(2016) Céline Hivelin et al.   Journal of Diabetes Research

Hormonal Responses to Cholinergic Input Are Different in Humans with and without Type 2 Diabetes Mellitus

(2016) Sara Chowdhury et al.   PLoS One

The mature/pro nerve growth factor ratio is decreased in the brain of diabetic rats: Analysis by ELISA methods

(2015) Marzia Soligo et al.   BRAIN RESEARCH

In vitroandin vivoregulation of synaptogenesis by the novel antidepressant spadin

(2015) C Devader et al.   BRITISH JOURNAL OF PHARMACOLOGY

Sortilin deficiency improves the metabolic phenotype and reduces hepatic steatosis of mice subjected to diet-induced obesity

(2015) Liane Rabinowich et al.   JOURNAL OF HEPATOLOGY

Role of K2P channels in stimulus-secretion coupling

(2014) Donghee Kim et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Revisiting the structure of the Vps10 domain of human sortilin and its interaction with neurotensin

(2014) Esben M. Quistgaard et al.   PROTEIN SCIENCE

Insulin responsiveness of glucose transporter 4 in 3T3-L1 cells depends on the presence of sortilin

(2013) Guanrong Huang et al.   MOLECULAR BIOLOGY OF THE CELL

Analysis of In Vitro Insulin-Resistance Models and Their Physiological Relevance to In Vivo Diet-Induced Adipose Insulin Resistance

(2013) Kinyui Alice Lo et al.   Cell Reports

Plasma Proneurotensin and Incidence of Diabetes, Cardiovascular Disease, Breast Cancer, and Mortality

(2012) Olle Melander et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Biogenesis and regulation of insulin-responsive vesicles containing GLUT4

(2010) Jonathan S Bogan et al.   CURRENT OPINION IN CELL BIOLOGY

Neurotensin is a regulator of insulin secretion in pancreatic beta-cells

(2010) Sophie Béraud-Dufour et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

ProNGF mediates death of Natural Killer cells through activation of the p75NTR–sortilin complex

(2010) Mary-Louise Rogers et al.   JOURNAL OF NEUROIMMUNOLOGY

Spadin, a Sortilin-Derived Peptide, Targeting Rodent TREK-1 Channels: A New Concept in the Antidepressant Drug Design

(2010) Jean Mazella et al.   PLOS BIOLOGY

Role of the JNK-interacting protein 1/islet brain 1 in cell degeneration in Alzheimer disease and diabetes

(2009) Nicole Beeler et al.   BRAIN RESEARCH BULLETIN

Involvement of TNF-α in abnormal adipocyte and muscle sortilin expression in obese mice and humans

(2009) V. Kaddai et al.   DIABETOLOGIA

JNK3 is abundant in insulin-secreting cells and protects against cytokine-induced apoptosis

(2009) S. Abdelli et al.   DIABETOLOGIA

Neurotensin receptor-2 and -3 are crucial for the anti-apoptotic effect of neurotensin on pancreatic β-TC3 cells

(2009) Sophie Béraud-Dufour et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Ligands bind to Sortilin in the tunnel of a ten-bladed β-propeller domain

(2009) Esben M Quistgaard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Neurotensin protects pancreatic beta cells from apoptosis

(2008) Thierry Coppola et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Self-assembly of Glut4 Storage Vesicles during Differentiation of 3T3-L1 Adipocytes

(2008) Jun Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Role of Sortilin in Myogenesis and Development of Insulin-responsive Glucose Transport System in C2C12 Myocytes

(2008) Miyako Ariga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY