Metabolism and Bioactivation of Corynoline With Characterization of the Glutathione/Cysteine Conjugate and Evaluation of Its Hepatotoxicity in Mice

Cytochromes P450 1A2 and 3A4 Catalyze the Metabolic Activation of Sunitinib

(2018) Gracia M. Amaya et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Biotransformation and bioactivation reactions – 2017 literature highlights

(2018) S. Cyrus Khojasteh et al.   DRUG METABOLISM REVIEWS

Reactive Metabolite-induced Protein Glutathionylation: a Potentially Novel Mechanism Underlying Acetaminophen Hepatotoxicity

(2018) Chun Yip CHAN et al.   MOLECULAR & CELLULAR PROTEOMICS

Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia

(2017) Alvin W. T. Ng et al.   Science Translational Medicine

Application of BACE1 immobilized enzyme reactor for the characterization of multifunctional alkaloids from Corydalis cava (Fumariaceae) as Alzheimer's disease targets

(2016) Jakub Chlebek et al.   FITOTERAPIA

Simultaneous determination of corynoline and acetylcorynoline in human urine by LC–MS/MS and its application to a urinary excretion study

(2016) Ruijuan Liu et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Corydalis bungeana Turcz. attenuates LPS-induced inflammatory responses via the suppression of NF-κB signaling pathway in vitro and in vivo

(2016) Xiao-Ting Zhai et al.   JOURNAL OF ETHNOPHARMACOLOGY

Study on the pharmacokinetic profiles of corynoline and its potential interaction in traditional Chinese medicine formula Shuanghua Baihe tablets in rats by LC–MS/MS

(2016) Ruijuan Liu et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Metabolomic Study on Idiosyncratic Liver Injury Induced by Different Extracts of Polygonum multiflorum in Rats Integrated with Pattern Recognition and Enriched Pathways Analysis

(2016) Chun-Yu Li et al.   Frontiers in Pharmacology

Detection of Reactive Metabolites Using Isotope-Labeled Glutathione Trapping and Simultaneous Neutral Loss and Precursor Ion Scanning with Ultra-High-Pressure Liquid Chromatography Triple Quadruple Mass Spectrometry

(2015) Ke Huang et al.   ANALYTICAL CHEMISTRY

Screening for anti-inflammatory components from Corydalis bungeana Turcz. based on macrophage binding combined with HPLC

(2015) Zi-Bo Dong et al.   BMC Complementary and Alternative Medicine

Herbal hepatotoxicity in traditional and modern medicine: actual key issues and new encouraging steps

(2015) Rolf Teschke et al.   Frontiers in Pharmacology

Bioactivation of Sitaxentan in Liver Microsomes, Hepatocytes, and Expressed Human P450s with Characterization of the Glutathione Conjugate by Liquid Chromatography Tandem Mass Spectrometry

(2013) John C. L. Erve et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Bioactivation of bisphenol A and its analogs (BPF, BPAF, BPZ and DMBPA) in human liver microsomes

(2013) Jan Schmidt et al.   TOXICOLOGY IN VITRO

Preparative isolation of alkaloids from Corydalis bungeana Turcz. by high-speed counter-current chromatography using stepwise elution

(2011) Lili Niu et al.   JOURNAL OF SEPARATION SCIENCE

Identification of cytochrome P450 (CYP) isoforms involved in the metabolism of corynoline, and assessment of its herb-drug interactions

(2010) Zhong-Ze Fang et al.   PHYTOTHERAPY RESEARCH