Synthetic Light-Activated Ion Channels for Optogenetic Activation and Inhibition

Hyperpolarization by activation of halorhodopsin results in enhanced synaptic transmission: Neuromuscular junction and CNS circuit

(2018) Matthew Mattingly et al.   PLoS One

FIMTrack: An open source tracking and locomotion analysis software for small animals

(2017) Benjamin Risse et al.   PLoS Computational Biology

Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons

(2017) Nicole Scholz et al.   eLife

How (not) to silence long-range projections with light

(2016) J Simon Wiegert et al.   NATURE NEUROSCIENCE

Biophysical constraints of optogenetic inhibition at presynaptic terminals

(2016) Mathias Mahn et al.   NATURE NEUROSCIENCE

Optogenetic control of endogenous Ca2+ channels in vivo

(2015) Taeyoon Kyung et al.   NATURE BIOTECHNOLOGY

Engineering of a light-gated potassium channel

(2015) C. Cosentino et al.   SCIENCE

Natural light-gated anion channels: A family of microbial rhodopsins for advanced optogenetics

(2015) E. G. Govorunova et al.   SCIENCE

The rhodopsin–guanylyl cyclase of the aquatic fungusBlastocladiella emersoniienables fast optical control of cGMP signaling

(2015) Ulrike Scheib et al.   Science Signaling

Optogenetic manipulation of cGMP in cells and animals by the tightly light-regulated guanylyl-cyclase opsin CyclOp

(2015) Shiqiang Gao et al.   Nature Communications

Near-infrared photoactivatable control of Ca2+ signaling and optogenetic immunomodulation

(2015) Lian He et al.   eLife

The rhodopsin–guanylyl cyclase of the aquatic fungusBlastocladiella emersoniienables fast optical control of cGMP signaling

(2015) Ulrike Scheib et al.   Science Signaling

Structure of the SthK Carboxy-Terminal Region Reveals a Gating Mechanism for Cyclic Nucleotide-Modulated Ion Channels

(2015) Divya Kesters et al.   PLoS One

Potency of Transgenic Effectors for Neurogenetic Manipulation in Drosophila Larvae

(2014) D. Pauls et al.   GENETICS

Independent optical excitation of distinct neural populations

(2014) Nathan C Klapoetke et al.   NATURE METHODS

Family of prokaryote cyclic nucleotide-modulated ion channels

(2014) M. Brams et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Channelrhodopsin-2-XXL, a powerful optogenetic tool for low-light applications

(2014) A. Dawydow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A fully genetically encoded protein architecture for optical control of peptide ligand concentration

(2014) Daniel Schmidt et al.   Nature Communications

ReaChR: a red-shifted variant of channelrhodopsin enables deep transcranial optogenetic excitation

(2013) John Y Lin et al.   NATURE NEUROSCIENCE

FIM, a Novel FTIR-Based Imaging Method for High Throughput Locomotion Analysis

(2013) Benjamin Risse et al.   PLoS One

Hebbian Plasticity Guides Maturation of Glutamate Receptor Fields In Vivo

(2013) Dmitrij Ljaschenko et al.   Cell Reports

Ultra light-sensitive and fast neuronal activation with the Ca2+-permeable channelrhodopsin CatCh

(2011) Sonja Kleinlogel et al.   NATURE NEUROSCIENCE

Molecular and Cellular Approaches for Diversifying and Extending Optogenetics

(2010) Viviana Gradinaru et al.   CELL

Natural and Engineered Photoactivated Nucleotidyl Cyclases for Optogenetic Applications

(2010) Min-Hyung Ryu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Light Modulation of Cellular cAMP by a Small Bacterial Photoactivated Adenylyl Cyclase, bPAC, of the Soil BacteriumBeggiatoa

(2010) Manuela Stierl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-performance genetically targetable optical neural silencing by light-driven proton pumps

(2010) Brian Y. Chow et al.   NATURE

Genomic mapping and expression patterns of C380, OK6 and D42 enhancer trap lines in the larval nervous system of Drosophila

(2009) Subhabrata Sanyal   GENE EXPRESSION PATTERNS

Temporally precise in vivo control of intracellular signalling

(2009) Raag D. Airan et al.   NATURE