Altered Synaptic Vesicle Release and Ca2+ Influx at Single Presynaptic Terminals of Cortical Neurons in a Knock-in Mouse Model of Huntington’s Disease

Reconstituting Corticostriatal Network on-a-Chip Reveals the Contribution of the Presynaptic Compartment to Huntington’s Disease

(2018) Amandine Virlogeux et al.   Cell Reports

Mitochondrial Quality Control in Neurodegenerative Diseases: Focus on Parkinson's Disease and Huntington's Disease

(2018) Sandra Franco-Iborra et al.   Frontiers in Neuroscience

Cortical Axonal Secretion of BDNF in the Striatum Is Disrupted in the Mutant-huntingtin Knock-in Mouse Model of Huntington's Disease

(2018) Hyungju Park   Experimental Neurobiology

Decreased BDNF Release in Cortical Neurons of a Knock-in Mouse Model of Huntington’s Disease

(2018) Chenglong Yu et al.   Scientific Reports

N-type Ca 2+ channels are affected by full-length mutant huntingtin expression in a mouse model of Huntington's disease

(2017) Flavia R. Silva et al.   NEUROBIOLOGY OF AGING

Synaptopathic mechanisms of neurodegeneration and dementia: Insights from Huntington’s disease

(2017) Shiraz Tyebji et al.   PROGRESS IN NEUROBIOLOGY

Enhanced Store-Operated Calcium Entry Leads to Striatal Synaptic Loss in a Huntington's Disease Mouse Model

(2016) J. Wu et al.   JOURNAL OF NEUROSCIENCE

A comparison of fluorescent Ca2+ indicators for imaging local Ca2+ signals in cultured cells

(2015) Jeffrey T. Lock et al.   CELL CALCIUM

Huntington Disease

(2015) Praveen Dayalu et al.   NEUROLOGIC CLINICS

Neuronal calcium signaling: function and dysfunction

(2014) Marisa Brini et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanisms of synaptic dysfunction and excitotoxicity in Huntington's disease

(2014) Marja D. Sepers et al.   DRUG DISCOVERY TODAY

A highly sensitive fluorescent indicator dye for calcium imaging of neural activityin vitroandin vivo

(2014) Mayumi Tada et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Impaired TrkB Receptor Signaling Underlies Corticostriatal Dysfunction in Huntington’s Disease

(2014) Joshua L. Plotkin et al.   NEURON

Neuronal Voltage-Gated Calcium Channels: Structure, Function, and Dysfunction

(2014) Brett A. Simms et al.   NEURON

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Neuronal toll-like receptor 4 signaling induces brain endothelial activation and neutrophil transmigration in vitro

(2012) Sophie Leow-Dyke et al.   Journal of Neuroinflammation

In Vivo Alterations in Calcium Buffering Capacity in Transgenic Mouse Model of Synucleinopathy

(2012) L. Reznichenko et al.   JOURNAL OF NEUROSCIENCE

Comprehensive Behavioral and Molecular Characterization of a New Knock-In Mouse Model of Huntington’s Disease: zQ175

(2012) Liliana B. Menalled et al.   PLoS One

Characterization of Neurophysiological and Behavioral Changes, MRI Brain Volumetry and 1H MRS in zQ175 Knock-In Mouse Model of Huntington's Disease

(2012) Taneli Heikkinen et al.   PLoS One

Influence of Synaptic Vesicle Position on Release Probability and Exocytotic Fusion Mode

(2012) H. Park et al.   SCIENCE

Independent Regulation of Basal Neurotransmitter Release Efficacy by Variable Ca2+ Influx and Bouton Size at Small Central Synapses

(2012) Yaroslav S. Ermolyuk et al.   PLOS BIOLOGY

Systematic Heterogeneity of Fractional Vesicle Pool Sizes and Release Rates of Hippocampal Synapses

(2011) Oliver Welzel et al.   BIOPHYSICAL JOURNAL

Increased Neurotransmitter Release at the Neuromuscular Junction in a Mouse Model of Polyglutamine Disease

(2011) J. L. Rozas et al.   JOURNAL OF NEUROSCIENCE

A readily retrievable pool of synaptic vesicles

(2011) Yunfeng Hua et al.   NATURE NEUROSCIENCE

Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function

(2011) L.A. Raymond et al.   NEUROSCIENCE

Voltage-Gated Calcium Channels

(2011) W. A. Catterall   Cold Spring Harbor Perspectives in Biology

Calcium Control of Neurotransmitter Release

(2011) T. C. Sudhof   Cold Spring Harbor Perspectives in Biology

Glutamate-induced alterations in Ca2+ signaling are modulated by mitochondrial Ca2+ handling capacity in brain slices of R6/1 transgenic mice

(2010) T. R. Rosenstock et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Early Increase in Extrasynaptic NMDA Receptor Signaling and Expression Contributes to Phenotype Onset in Huntington's Disease Mice

(2010) Austen J. Milnerwood et al.   NEURON

Functional Heterogeneity at Dopamine Release Sites

(2009) J. A. Daniel et al.   JOURNAL OF NEUROSCIENCE

Age-Dependent Alterations of Corticostriatal Activity in the YAC128 Mouse Model of Huntington Disease

(2009) P. R. Joshi et al.   JOURNAL OF NEUROSCIENCE

Brain-derived neurotrophic factor in neurodegenerative diseases

(2009) Chiara Zuccato et al.   Nature Reviews Neurology

The probability of neurotransmitter release: variability and feedback control at single synapses

(2009) Tiago Branco et al.   NATURE REVIEWS NEUROSCIENCE

The Dynamic Control of Kiss-And-Run and Vesicular Reuse Probed with Single Nanoparticles

(2009) Q. Zhang et al.   SCIENCE

Calcium signaling and neurodegenerative diseases

(2009) Ilya Bezprozvanny   TRENDS IN MOLECULAR MEDICINE

Differential electrophysiological properties of dopamine D1 and D2 receptor-containing striatal medium-sized spiny neurons

(2008) Carlos Cepeda et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Spontaneous and Evoked Glutamate Release Activates Two Populations of NMDA Receptors with Limited Overlap

(2008) D. Atasoy et al.   JOURNAL OF NEUROSCIENCE

Dichotomous Anatomical Properties of Adult Striatal Medium Spiny Neurons

(2008) T. S. Gertler et al.   JOURNAL OF NEUROSCIENCE

Suppression of Neurodegeneration and Increased Neurotransmission Caused by Expanded Full-Length Huntingtin Accumulating in the Cytoplasm

(2008) Eliana Romero et al.   NEURON

Local Dendritic Activity Sets Release Probability at Hippocampal Synapses

(2008) Tiago Branco et al.   NEURON